With all the testing I have seen with peptides, getting the IGF-1 into the 300 - 400 range is not going to happen. But they will certainly put it into a abover aevrage range.
I believe some of the hGH carpal tunnel issues can be prevented.
Hoffman DM, Crampton L, Sernia C, et al.
Short-term growth hormone (GH) treatment of GH-deficient adults increases body sodium and extracellular water, but not blood pressure. J Clin Endocrinol Metab1996;81:1123–8.
Initiation of GH treatment in adults is frequently complicated by the development of symptomatic fluid retention. To investigate the mechanism and extent of fluid retention that occurs with dosages of GH used in the treatment of GH-deficient adults, we conducted a double blind study in which...
pubmed.ncbi.nlm.nih.gov
"We conclude that 1) sodium retention is a physiological effect of GH, but does not cause an acute rise in blood pressure; and 2) the mechanism of sodium and fluid retention is not primarily due to enhanced aldosterone secretion or inhibition of ANP release, but more likely to a direct renal tubular effect."
So GH causes an increase in water absorption by the gut and sodium retention leading to extracellular fluid accumulation, carpal tunnel syndrome but apparently not hypertension.
J. Moller, N. Moller, E. Frandsen, T. Wolthers, J. O. Jorgensen, J. S. Christiansen.
Blockade of the renin-angiotensin-aldosterone system prevents growth hormone-induced fluid retention in humans. American Journal of Physiology - Endocrinology and Metabolism Published 1 May 1997 Vol. 272 no. 5, E803-E808.
Monotherapy with an angiotensin-converting enzyme inhibitor (ACEi) or an angiotensin II receptor blocker (ARB) remains valid in all the guidelines, whereas their dual combination has been discarded due to the absence of proven benefits in high CV risk patients and in patients with chronic kidney...
pubmed.ncbi.nlm.nih.gov
I found I could use Angiotensin II receptor antagonists to lower the fluid retention while taking hGH.