Feeling depressed the day following DHEA supplementation

cigpk · Oct 29, 2019

My doc suggested 25 mg DHEA at night for sleep. Last night I gave it a shot and slept pretty good. This morning I felt pretty groggy and all day long I have felt drowsy/down/flat/depressed.

Is this due to the cortisol suppression from DHEA? I’m thinking maybe I’ll cut the dose down to 10 mg and give it another shot because the sleep benefit was nice. I just didn’t enjoy the after effects.

Starplex · Oct 29, 2019

Maybe give it a week or so to let your body adjust before throwing it in the ditch.

captain · Oct 29, 2019

That is a symptom of taking too much DHEA.

RPellerin · Oct 30, 2019

DHEA makes me feel agitated, even at 5mg micronized.
Not everyone can tolerate it.

Vince · Oct 30, 2019

Have you had your DHEA levels checked? I would assume your levels are low and that's why you're supplementing with it.

cigpk · Oct 30, 2019

Vince said:
Have you had your DHEA levels checked? I would assume your levels are low and that's why you're supplementing with it.

Mid range. PA at Defy recommended solely for increasing sleep quality.

Vince · Oct 31, 2019

cigpk said:
Mid range. PA at Defy recommended solely for increasing sleep quality.

If your levels are mid range, then DHEA is not needed. If you're having bad issues supplementing with it. I would stop taking dhea.

Vince Carter · Oct 31, 2019

I agree with everyone else here and add that in Men DHEA can very easily be converted to Estrogen. Some times the type of DHEA like an oral micronized or transdermal can limit conversion but it's still there.

evansjamesk · Nov 6, 2019

According to Dr. Crisler, DHEA can be converted to estrogen if taken orally. You might want to try a sublingual version instead.

TorontoTRT · Nov 6, 2019

I take 100 mg nightly now for a week and all of a sudden I have daily morning wood. For the last 6 months I've been taking it in the morning with no noticeable pros or cons. It's 100 mg slow release compounded.

Pfizerclot · Nov 29, 2022

TorontoTRT said:
ek and all of a sudden I have daily morning wood. For the last 6 months I've been taking it in the morning with no noticeable pros or cons. It's 100 m

What happends when you quit? upregulated or down regulated?