Dialed in on Testosterone Propionate, How to Switch to Cypionate

[FunkOdyssey]

It might work in some healthy individuals, but it's more of a stretch for those suffering from secondary hypogonadism, who have a reduced natural set point for testosterone.

It's the estradiol setpoint that is most impactful here, and this usually doesn't differ for men with secondary hypogonadism. In my view, the only reason most men with secondary hypogonadism have it is because they are able to reach their estradiol setpoint with less testosterone, because they aromatize like crazy, because they're obese and/or metabolically unhealthy with high insulin levels (insulin promotes aromatase expression).

It is a peculiar thing that the male HPTA system seems to view testosterone as primarily a means to the end of achieving a desired level of estradiol.

By the way, my concerns about enclomiphene have gotten the better of me and I am phasing it out.

Can you elaborate on these? Did you encounter adverse effects, or are these mainly theoretical concerns?