DHEA Supplementation

DHEA Supplementation
Dehydroepiandrosterone: DHEA
As presented by Dr. Neal Rouzier, M.D.

Here's a great reason to add DHEA to your protocol.

DHEA is a hormone secreted primarily by the adrenal glands. It results in a shift of a catabolic state to an anabolic or protein building state.

· It reduces cardiovascular risks by increasing lipolyses (decrease visceral fat).
· It stimulates the immune system, restores sexual vitality, improves moods, decreases
cholesterol and body fat.
· It improves memory, increases energy, and has anti-cancer properties by enhancing the
immune system.
· It is an endocrine precursor to other hormones, prevents immuno-senescence, loss of sleep,
osteoporosis, atherosclerosis.
· DHEA reduces insulin requirement
· Adrenal hormone anabolic vs. catabolic metabolism
· Restores immunity
· Prevents osteoporosis, increases bone density
· Prevents cancer in lab animals
· Prevents diabetes & heart disease
· Decreases visceral fat
· Improves mood & well-being
· Improves energy & memory
· Slows aging process in lab animals
· Prevents lipid peroxidation = antioxidant
· Endocrine precursor to T.P.E.
· 7-keto DHEA is not a precursor to other HRT = avoid
· Neurotransmitter (recently discovered)
· Presently pending FDA approval for Lupus (Prasterone)

Clinically substantiated uses of DHEA include replacement for:
· Low DHEA levels
· Chronic disease
· Adrenal exhaustion or corticosteroid therapy
· SLE
· Improving bone density
· Improving depression & mood disorders
· Enhancing immune response by activating T-cells
· Improving well-being
· Decreasing cardiovascular risk
· Improving erectile dysfunction
· Anyone over 40
· DHEA has never been shown to reverse the aging process
· Nevertheless DHEA is important for preventive medicine
· DHEA inhibits synthesis of thromboxane A2, reduces plasminogen activator inhibitor, and
tissue plasminogen activator – all decreasing platelet aggregation and ischemia.

Administration:
Men<200lb: 50mg AM
Men>200lb: 75-100mg AM
Women <50yo: 10-15mg AM
Women >50yo: 25mg AM

IMPORTANT:
DHEA Serum Levels
MEN
· Range 100-600
· Optimal 500-600
WOMEN
· Range 50-300
· Optimal 200-250
Higher levels in women predispose them to side effects – therefore stay low.
· Monitor monthly until optimal
· Assure correct dose and compliance
· Measure DHEA-S and not DHEA
· Side effects: acne, hirsutism
· Tx: Lower dose or take QOD Spironolactone 100 mg/day
· Contraindicated in sex hormone responsive tumors – breast, ovarian, uterine, prostate
· Conversion to T.P.E.?
· DHEA raises testosterone levels in women slightly, yet not in men
· DHEA raises estradiol slightly in men
Indications:
· Over age 40 for health protection
· Preventive medicine and well-being
· Symptoms of aging, mood & depression
· Cause the medical literature suggests it if we want to live longer, happier, healthier



Note from Nelson Vergel:

I am not convinced that DHEA has that many benefits unless you supplement due to low levels. The ratio of cortisol to DHEA is really what matters since each of those hormones are produced by the adrenal glands to balance each other.

I expand here:

DHEA Supplementation in Men: What Do Studies Show?

Dehydroepiandrosterone (DHEA) DHEA is a steroid prohormone produced by the adrenal glands and transformed in target tissue through intracrine mechanisms to androgens or estrogens. Plasma DHEA levels decline with age. By the age of 70–80 years, levels may be as low as 10%–20% of...

www.excelmale.com

 

The same for me, DHEA even lower my E2 level... I suffer from low e2 since I crashed with exemestane/arimidex with RAD140..
I try to find the way to increase my e2, I have very low shbg and my freeT is almost triple so increase T dose in NO NO for me. What do you think? Clomid raise estrogen?

I also fucked up my aromatisation permanently with exemestane 2-3 years ago still suffering. Before exemestane shit i was over aromatiser. Are you in trt? Clomid is horrific idea for that. I’ve tried it in various dosages made me libido non existant and bad depression and caused more joint pain than i usually have. Also lowers gh and igf1 levels not good.
Read low/crushed estrogen threads there are some tips and tricks you can try to see if them work for you.

 

What are your before and after supplementing levels of dhea

Before 4,8 after 10-11 (ref range 4,34 – 8). I also tried up my dose and it lower it again, not so much but definitely Yes, level was 16 with bigger dose.

 

I also fucked up my aromatisation permanently with exemestane 2-3 years ago still suffering. Before exemestane shit i was over aromatiser. Are you in trt? Clomid is horrific idea for that. I’ve tried it in various dosages made me libido non existant and bad depression and caused more joint pain than i usually have. Also lowers gh and igf1 levels not good.
Read low/crushed estrogen threads there are some tips and tricks you can try to see if them work for you.

Yes I am on trt. My GH level is low too and 4 iu of HGH seems to help little bit with aromatisation. Than you!

 

I also fucked up my aromatisation permanently with exemestane 2-3 years ago still suffering. Before exemestane shit i was over aromatiser. Are you in trt? Clomid is horrific idea for that. I’ve tried it in various dosages made me libido non existant and bad depression and caused more joint pain than i usually have. Also lowers gh and igf1 levels not good.
Read low/crushed estrogen threads there are some tips and tricks you can try to see if them work for you.

Is there any specific thread you meant? Can you share please.

 

Gene, you have a lot of experience with this. Some time back I took DHEA and bloated up within days. Of course I stopped taking it yet at 45, I wonder if I should try again at a lower dose and give it some time? Currently on cyp only @ 50mg every 3.5 days.

The same with me. My ankles and feet also swelled up. I've tried DHEA several times and it's always the same(10 to 25 mg). Too bad, because it does restore my erections. Now doing topical, as I've read it can be as effective as oral. I open a 25 mg capsule, mix it with a bit of olive oil and rub it into the side of my chest and the armpit. My recent lab, before taking DHEA, showed my level at 224 mcg/dL Age is 70.

 

LOL

Well, my beard is getting close to my eyes and my ears are getting covered in hair. Unsettling.

Learn to play the guitar and channel Jerry Garcia.

 

Is there any specific thread you meant? Can you share please.

this:
Help increasing Estradiol

 

What are your before and after supplementing levels of dhea

I would attack the problem directly and supplement with E2 cream.

Of course, acquiring the cream might be more difficult but I am thinking you could find it somehow.

If I did that, after a 3+ months, I would suspend supplementing long enough to see if my E2 was back to normal.

 

The same with me. My ankles and feet also swelled up. I've tried DHEA several times and it's always the same(10 to 25 mg). Too bad, because it does restore my erections. Now doing topical, as I've read it can be as effective as oral. I open a 25 mg capsule, mix it with a bit of olive oil and rub it into the side of my chest and the armpit. My recent lab, before taking DHEA, showed my level at 224 mcg/dL Age is 70.

I'm also experimenting with transdermal dhea. Alphagainz has it already in a transdermal solution and works quickly and well. I'm still figuring out the right dose, but >25mg is definitely too much for me. About 12mg bloats mildly but gives other benefits TRT had been missing.

 

I'm also experimenting with transdermal dhea. Alphagainz has it already in a transdermal solution and works quickly and well. I'm still figuring out the right dose, but >25mg is definitely too much for me. About 12mg bloats mildly but gives other benefits TRT had been missing.

I'm hypersensitive to additives/preservatives even in topical formulations so I just homebrew it, lol. I'm trying it, now, on my scrotum in attempt to increase DHT.

 

been taking 25mg DHEA in the evening, sleep is great. for 1+ month or so.
my DHEA-S levels came at 345.
I've notice some people here got lower levels at higher doses, I am wondering if supplement quality plays a role here. I do use PureEncapsulations for DHEA, not advertising for this brand, and I only have 2 supplements from them.

 

been taking 25mg DHEA in the evening, sleep is great. for 1+ month or so.
my DHEA-S levels came at 345.
I've notice some people here got lower levels at higher doses, I am wondering if supplement quality plays a role here. I do use PureEncapsulations for DHEA, not advertising for this brand, and I only have 2 supplements from them.

I like that brand as well for several things.

 

All hormone levels are meant to be lower as we get older, it’s how your body accelerates aging so that you die and you don’t take up valuable resources anymore. These resources are needed for people that are still fertile, and can pass on healthy DNA and keep our species alive. But we are here on this forum because we are trying to fight the aging process, so I don’t think you’re going to get anybody to agree with your theory that we would potentially be healthier if we kept certain hormone levels lower, and only replaced other specific hormones. All due respect obviously.

Hormones getting lower with age are a consequence of one's organism degradation, which doesn't have the ressources and raw materials necessary to produce said hormones.

The oldest father that ever produced a baby was 96 years old, in India, a few years ago.
His diet consisted of raw milk, raw eggs, and raw almonds. That's it.

The fact that the vast majority of men have decreasing hormone levels shouldn't be considered natural or an example to follow.
They are just a consequence of poor diets and poor lifestyles.

Absent a correction of either diet or lifestyle, one can supplement hormones to restore youthful levels.
It won't cancel the degradation process brought upon by the poor diet, but at least you will feel happier in your degraded body.

 

Hormones getting lower with age are a consequence of one's organism degradation, which doesn't have the ressources and raw materials necessary to produce said hormones.

The oldest father that ever produced a baby was 96 years old, in India, a few years ago.
His diet consisted of raw milk, raw eggs, and raw almonds. That's it.

The fact that the vast majority of men have decreasing hormone levels shouldn't be considered natural or an example to follow.
They are just a consequence of poor diets and poor lifestyles.

Absent a correction of either diet or lifestyle, one can supplement hormones to restore youthful levels.
It won't cancel the degradation process brought upon by the poor diet, but at least you will feel happier in your degraded body.

That’s interesting about his diet. I’m a firm believer in the optimal diet being a raw carnivore diet with specific carb sources eaten in a cyclical manner. So not all the time, but u also don’t want to be in ketosis forever either. So raw milk and raw eggs line right up with that type of diet. The almonds are doing more harm than good, but sounds like the raw milk and eggs are enough to minimize most of the negative effects of the almonds.

 

That’s interesting about his diet. I’m a firm believer in the optimal diet being a raw carnivore diet with specific carb sources eaten in a cyclical manner. So not all the time, but u also don’t want to be in ketosis forever either. So raw milk and raw eggs line right up with that type of diet. The almonds are doing more harm than good, but sounds like the raw milk and eggs are enough to minimize most of the negative effects of the almonds.

What's wrong with almonds? I drink almond milk and sometimes eat almond milk yogurt trying avoid lactose. Thanks.

 

That’s interesting about his diet. I’m a firm believer in the optimal diet being a raw carnivore diet with specific carb sources eaten in a cyclical manner. So not all the time, but u also don’t want to be in ketosis forever either. So raw milk and raw eggs line right up with that type of diet. The almonds are doing more harm than good, but sounds like the raw milk and eggs are enough to minimize most of the negative effects of the almonds.

Completely agree. I just don't have the balls to go completely raw carnivore with my current social life.
Raw milk and raw eggs with cooked carnivore diet is where I'm at, feeling great.

 

What's wrong with almonds? I drink almond milk and sometimes eat almond milk yogurt trying avoid lactose. Thanks.

Everything is wrong with almonds and other nuts and seeds, let alone grains.
Read about Aajonus Vonderplanitz, it would be too long to explain the diet basics here.

 

What's wrong with almonds? I drink almond milk and sometimes eat almond milk yogurt trying avoid lactose. Thanks.

I agree with zibernet, it’s a bit complicated to sum up real quick on here, but once u learn what seeds actually are, it’s obvious that we’re not supposed to be eating them. I haven’t checked out the guy he recommended, but I definitely am going to. The person that I’ve found explains it the best so far is Dr Paul Saladino. The guy is a legit computer. Idk how he remembers everything he does. Here’s a quick video where he talks about seeds and nuts, IIRC, but if u really want to understand why humans shouldn’t be consuming seeds and nuts u definitely want to dig deeper into all the content Dr Paul Saladino has out there. He has a YouTube channel as well as a podcast. Here’s the quick video where he talks about seeds and nuts tho.

Also, if ur sensitive to lactose, u may want to look into organic raw grassfed dairy. It’s very healthy for u, and may not bother u like processed commercial dairy does. When u pasteurize dairy u kill all the good bacteria and enzymes that are there to help digestive the dairy properly. Commercial dairy kills all the good bacteria and enzymes that help us digest the lactose in dairy. So a lot of people that think there lactose intolerant are really just unable to digest commercial dairy properly, but some have no problem digesting raw organic grassfed dairy. The homogenization process also degrades the dairy and makes it difficult for us to digest. Overall, processed commercial dairy is one of the worst foods a human can intake. It’s just a dead food that is going to increase inflammation. Raw organic grassfed dairy, on the other hand, is one of the oldest super foods there is. It doesn’t even have to be organic, but obv preferred. Being raw and grassfed is what’s mostly important. There’s a tribe in Africa that has been studied, due to how extremely healthy they are, and they mainly eat only raw cow milk mixed with cow blood, and I believe raw honey when it’s available.

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Completely agree. I just don't have the balls to go completely raw carnivore with my current social life.
Raw milk and raw eggs with cooked carnivore diet is where I'm at, feeling great.

Man ur doing better than I am I can tell u that lol. I know what the healthiest diet is for man, but doesn’t mean I currently follow it lol. I do try to stay as close to carnivore as I can tho. But the gym and building muscle is important to me, and I have a pretty crazy work schedule and social schedule, so haven’t been able to take the full carnivore plunge just yet. I do plan on doing so at some point tho. Currently eating the same exact thing everyday. 5 whole eggs, 2 just egg whites, white rice, honey for breakfast, followed by some fruit for desert. For lunch it’s cooked steak and rice, and then fruit for desert, and dinner is steak, rice and honey, and fruit for desert. Haven’t been able to get to the farmers market in a while, but when I can I always pickup some grassfed raw milk. Oh and I eat 1 ounce of organic raw grassfed cheese everyday.

So how many raw eggs do u do? Do u eat the whites raw too? Do u just crack them open and put them in ur mouth and swallow them? I don’t do the egg whites raw, due to worrying about the stuff that inhibits biotin supposedly that’s in them. What I do is I’ll eat 2 yolks raw just by swallowing them, put the two whites from them in a pan to cook, then crack 3 whole eggs in the pan to cook, and then just two whites in the pan to cook and throw 2 of the yolks away. So I eat 7 eggs total per day, but only 5 yolks

 

Man ur doing better than I am I can tell h that lol. I know what the healthiest diet is for man, but doesn’t mean I currently follow it lol. I do try to stay as close to carnivore as I can tho. But the gym and building muscle is important to me, and I have a pretty crazy work schedule and social schedule, so haven’t been able to take the full carnivore plunge just yet. I do plan on doing so at some point tho. Currently eating the same exact thing everyday. 5 whole eggs, 2 just egg whites, white rice, honey for breakfast, followed by some fruit for desert. For lunch it’s cooked steak and rice, and then fruit for desert, and dinner is steak, rice and honey, and fruit for desert. Haven’t been able to get to the farmers market in a while, but when I can I always pickup some grassfed raw milk. Oh and I eat 1 ounce of organic raw grassfed cheese everyday.

So how many raw eggs do u do? Do u eat the whites raw too? Do u just crack them open and put them in ur mouth and swallow them? I don’t do the egg whites raw, due to worrying about the stuff that inhibits biotin supposedly that’s in them. What I do is I’ll eat 2 yolks raw just by swallowing them, put the two whites from them in a pan to cook, then crack 3 whole eggs in the pan to cook, and then just two whites in the pan to cook and throw 2 of the yolks away. So I eat 7 eggs total per day, but only 5 yolks

The whole "egg white inhibits biotin" is BS. Nature doesn't fuck up.
I put them in raw milk with raw honey to make a milkshake.