No need to donate with a HCT of 48. IMO take iron supplements with Vit C and bovine spleen.OMG this thread is so powerful. I was having very good energy with TRT but after blood donation (I'm scared of 48 HCT) suddenly I feel fatigued and can't perform like before. My ferritin is 12 as of yesterday. Also, I'm eating a lot of eggs every day,, never before I knew it causes iron malabsorption.