You might want to try lower and less frequent doses of topical progesterone cream. I started with it several months ago at 1 pump (20mg) sscrotal application daily before bed and it seemed to help with calmness, etc. for a couple of weeks, then estrogen levels jumped up and caused problems. High doses of progesterone get eventually converted to estrogen. Found out that the half-life for topical applied progesterone is 30-40 hours, so dropped my dose to .25 pumps (5 mg) every other night. For the last few months this has worked well, so far. Currently take Test cypionate 62mg SQ twice weekly, 12,5mg DHEA daily, .21mg Anastrazole daily, NO HCG and 5mg progesterone scrotally every other night. Been on TRT for 8 years, 65 yr old, 6' 1", 220lb, total Test 550, E2 LC/MS Labcorp 58. I believe that the addition of DHEA and progesterone fill in some of the gaps that TRT causes.