post #26
I’ve been on nandrolone base for 1 1/2 years now. 28 mg per day along with 4 mg test. No libido or mental issues..
Highly doubtful 4 mg T daily (28 mg/week) is going to have your TT/FT level let alone estradiol high enough.
You can clearly see your estradiol is too low!
Would tread lightly on running your estradiol too low especially when it comes to long-term bone and tendon health.
Most in the know would not let it get below 20 pg/mL .
You have no clue where your TT truly sits as you had it tested using the wrong assay the electrochemiluminescence immunoassay (ECLIA) which will pick up the ND as T and skew your results
You would need to use the most accurate assay LC/MS-MS-No upper limit.
As I have stated numerous times on the forum over the years any time one adds ND to a T-only protocol it is critical to use the most accurate assays for TT (LC-MS/MS) and FT (Equilibrium Dialysis or Ultrafiltration) otherwise your results will be skewed and you will have absolutely no idea where your TT/FT level truly sits.
Both assays are critical and need to be used when adding nandrolone to a T-only protocol.
Just to be clear no AAS would be a testosterone substitution.
The main reason testosterone is used for replacement therapy over nandrolone let alone any other AAS is that testosterone drugs provide a hormone that is already produced in the body.
More importantly, its metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterone-beneficial effects on (cardiovascular health, brain health, libido, erectile function, bone health, tendon health, immune system, lipids, and body composition).
*Natural testosterone is viewed as the best androgen for substitution in hypogonadal men. The reason behind the selection is that testosterone can be converted to DHT and E2, thus developing the full spectrum of testosterone activities in long-term substitution
Yes some men will struggle on a T only protocol especially when it comes to running high-end/high FT levels and may fare much better using ND as the base with <100 mg T/week.
The downfall here is in many cases they end up running too low a T-dose with the ND and their estradiol ends up being too low which is not optimal for long-term health especially when it comes to bone/tendons.
If anything I would retest your TT/FT using the most accurate assays so you can see where they truly sit.
28 mg TC is an absurdly low weekly dose!
Late Onset Hypogonadism (LOH): bone health Abstract Background. Bone health is underdiagnosed and undermanaged in men. Bone loss occurs in men with hypogonadism and in aging men. Thus, patients with a diagnosis of late-onset hypogonadism (LOH) are at risk of osteoporosis and osteoporotic...
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post #2
Testosterone is important for the bones! One of the things physicians should look for in men with low bone density is testosterone levels. Men who have low levels of testosterone are at risk for osteoporosis. However, recent studies have shown that men on testosterone therapy who are...
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