Maximus: Oral TRT+ (native T + enclomiphene + pregnenolone)

[BigBeard411]

can the pill be chewed? I can't swallow entire pills.

Also, when i was on clomid the eye floaters I already had become exacerbated. Blood tests also showed my IGF-1 halving, which I found was previously reported in the literature when using clomid. Does enclomiphene usage result in this too?

Interestingly, I spoke to an eye doctor about clomid eye floaters and he said he has never heard of such a thing and doesn't see how it would affect floaters.

Also, another MD that prescribes clomid said not a single patient complained of that. Could it be i just became hyper-aware of the floaters i already had?

 

[Nelson Vergel]

clomid the eye floaters

Some discussions here: Enclomiphene - eye floaters?

 

[GeauxBears]

can the pill be chewed? I can't swallow entire pills.

Also, when i was on clomid the eye floaters I already had become exacerbated. Blood tests also showed my IGF-1 halving, which I found was previously reported in the literature when using clomid. Does enclomiphene usage result in this too?

Interestingly, I spoke to an eye doctor about clomid eye floaters and he said he has never heard of such a thing and doesn't see how it would affect floaters.

Also, another MD that prescribes clomid said not a single patient complained of that. Could it be i just became hyper-aware of the floaters i already had?

For what it's worth, I ran a trial of clomid several years ago before going onto TRT and experienced mild eye floaters. Since January of this year, I've been on a restart protocol - enclomiphene 25mg only, and have had no eye floaters.

 

[granger]

as mentioned lower dosage is needed buccally as it has HIGHER absorbtion...LESS first pass aswell..

 

[Seagal]

The blood sampling device is a game changer

 

[Cataceous]

... Blood tests also showed my IGF-1 halving, which I found was previously reported in the literature when using clomid. Does enclomiphene usage result in this too?
...

Yes, enclomiphene reduces IGF-1. This was observed in the clinical trials, and I have experienced it as well. It's not necessarily a bad thing — with respect to longevity — if you end up only a little below average. But if you have other priorities, such as body building, then you'd probably want to push it back up with a GH secretagogue.

 

[docc]

can the pill be chewed? I can't swallow entire pills.

Also, when i was on clomid the eye floaters I already had become exacerbated. Blood tests also showed my IGF-1 halving, which I found was previously reported in the literature when using clomid. Does enclomiphene usage result in this too?

Interestingly, I spoke to an eye doctor about clomid eye floaters and he said he has never heard of such a thing and doesn't see how it would affect floaters.

Also, another MD that prescribes clomid said not a single patient complained of that. Could it be i just became hyper-aware of the floaters i already had?

That's a great question, I'll have to ask the pharmacist. Though you can learn to swallow pills with these tricks:

Two tricks to make it easier to swallow pills - Harvard Health

...

www.health.harvard.edu

76% of people report having floaters. Most people don't notice them until they're paying attetion to them, so yes its likely you just became hyperaware.

Clomid has more side effects than enclomiphene, as verified in two clinical trials, so most of the side effects are due to the zuclomiphene isomer. Ocular side effects have never been noted in the literature on enclomiphene, nor in our clinical practice with any significant frequency.

 

[docc]

The blood sampling device is a game changer

Yeah, it's pretty amazing you can get Quest/LabCorp level accuracy at home now. I never need to go into the lab anymore unless I need lipids or something else measured.

 

[docc]

Yes, enclomiphene reduces IGF-1. This was observed in the clinical trials, and I have experienced it as well. It's not necessarily a bad thing — with respect to longevity — if you end up only a little below average. But if you have other priorities, such as body building, then you'd probably want to push it back up with a GH secretagogue.

Testosterone itself increases IGF-1 and can counteracts the decrease from Enclomiphene. My own labs show no difference in IGF-1 from baseline (no drugs) on the combination of a higher dose of testosterone + lower dose of enclomiphene.

 

[DixieWrecked]

I'm actually getting pretty darn interested in this. I got a question for systemlord.

I'm on Jaetnzo @237 mg twice daily, or 3318 mg per week.

What benefits did you notice from switching to jatenzo? Libido and erections improved from injections?

 

[DixieWrecked]

Yeah, it's pretty amazing you can get Quest/LabCorp level accuracy at home now. I never need to go into the lab anymore unless I need lipids or something else measured.

If I'm on injections now and want to switch to this program, will I qualify if my testosterone is above range on labs? I'd like to transition seamlessly if I try it

 

[Systemlord]

What benefits did you notice from switching to jatenzo? Libido and erections improved from injections?

The benefits, I noticed immediately were smoother sailing to a steady state in 7 days. No ups and downs like on injections, which goes on for weeks.

Definitely improvement in libido and erections, which was mostly absent on injections beyond the first week. Also Jatenzo nets you higher DHT than with injections.

I would try to aim for a higher than mid range at your midpoint or 6 hours.

Yesterday I got 592 ng/dL at 5 hours. Estrogen was 18 pg/mL and will rectify that now that I’ve stopped daily Cialis. I feel so much better after stopping daily Cialis!

 

[docc]

If I'm on injections now and want to switch to this program, will I qualify if my testosterone is above range on labs? I'd like to transition seamlessly if I try it

The doc may need to see a clean baseline that's within range, if done within the last 6 months. Otherwise you'd have to go off for a week and retest.

 

[DixieWrecked]

The doc may need to see a clean baseline that's within range, if done within the last 6 months. Otherwise you'd have to go off for a week and retest.

The blood work one week after stopping trt be equally as worthless. That wouldn't be a baseline reading either. Natural baseline would take months to reach. Is that practice just a legal cya thing?

 

[Phil Goodman]

If I'm on injections now and want to switch to this program, will I qualify if my testosterone is above range on labs? I'd like to transition seamlessly if I try it

If you do switch over I’ll be interested to hear how it goes. As someone with a lot of experience I’d like to hear your thoughts on how it compares to other protocols. I’m not really looking to change at the moment because I’m dialed in really good and also because I generally don’t like to be on the frontlines when it comes to medicines/treatments. But if it is an actual breakthrough in the trt realm offering the benefits it claims instead of just a fad it’s something I might consider down the road.

 

[DixieWrecked]

If you do switch over I’ll be interested to hear how it goes. As someone with a lot of experience I’d like to hear your thoughts on how it compares to other protocols. I’m not really looking to change at the moment because I’m dialed in really good and also because I generally don’t like to be on the frontlines when it comes to medicines/treatments. But if it is an actual breakthrough in the trt realm offering the benefits it claims instead of just a fad it’s something I might consider down the road.

Will do. I have been surfing different forums and I have found a few anecdotes where people have been running enclomiphene with their cypionate and have mid-high lh/fsh. I am going to continue with my protocol (Prop) but drop the HCG because I don't like it anyway and switch to enclomiphene which I have some from Hallendale. I will get tested in about a month and let yall know how it goes. Plan on taking 12.5mg enclomiphene eod at night time.

I'm having trouble finding the video but Dr. Mark Gordon uses clomid with his patients and he says it works to raise lh/fsh while on TRT.

 

[Guided_by_Voices]

Will do. I have been surfing different forums and I have found a few anecdotes where people have been running enclomiphene with their cypionate and have mid-high lh/fsh. I am going to continue with my protocol (Prop) but drop the HCG because I don't like it anyway and switch to enclomiphene which I have some from Hallendale. I will get tested in about a month and let yall know how it goes. Plan on taking 12.5mg enclomiphene eod at night time.

I'm having trouble finding the video but Dr. Mark Gordon uses clomid with his patients and he says it works to raise lh/fsh while on TRT.

This below is one of his videos where he mentions clomid. In general he thinks having zero LH for long periods is a bad idea, if I understand him correctly.

I just listened to Mike Mahler's latest interview with Dr. Mark Gordon and he said that Ibuprofen can damage the leydig cell in the testes, so the approaches above may depend on whether someone has this issue. He uses high amounts of clomid (starting at 50 MG and gradually lowering the dose) to "restart" the leydig cells. I am going to try to completely stop ibuprofen and shift to occasional aspirin instead.
The video is below.

 

[DixieWrecked]

@Guided_by_Voices thats the one! He says that moderate doses of Test Cyp still allow for Clomid to work to raise LH/FSH. I'd much rather do low dose enclomiphene to get the entire HPTA online as long as the doses are low enough. I really hate HCG.

 

[BigBeard411]

Yes, enclomiphene reduces IGF-1. This was observed in the clinical trials, and I have experienced it as well. It's not necessarily a bad thing — with respect to longevity — if you end up only a little below average. But if you have other priorities, such as body building, then you'd probably want to push it back up with a GH secretagogue.

what GH secretagogue would you recommend?

 

[Cataceous]

what GH secretagogue would you recommend?

I like ipamorelin, though I've got to admit that a single daily dose of 300 mcg isn't moving IGF-1 very much for me. Ibutamoren is another option if you want to be more aggressive.