Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack​

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

• Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
• Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
• Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages

 

I was up to 146/94. About 10 days ago infave up caffeine cold turkey. In our part of Florida there are a lot of Race-Trac branded gas stations. They carry a low carb energy drink right in the fountain soda area. I was getting 3 52 ounce drinks oer day. I just had to stop Robb Wolf once didna podcast on Adrenal Fatigue abd since i wasn't sure caffeine was affecting me anymore. Anyway the idea is to do a 30 day reset and introduce it slowly such as morning coffee.

Anyway went to my family practice doc and I was 105/76 the lowest I can recall.

Interestingly he mentioned that he is willing to prescribe test but not at the does I am taking which is 400 ccs per week. This is a 2 on the standard syringe. He said his folks are typically 100-200. Frankly I might be pretty high right now I hoping his bloodwork panel tests for it. Costco seems to have risen but I can shop around. I was about due to be lowered anyway. If I can sweet talk him into the 200cc i might but I digress I was just very excited by the results.

 

cc's are not doses...how many milligrams?

 

I read over on PeakT that there can be a relationship between citrulline and cancer cells. Curious, I found some papers that seem to indicate that a possible treatment of certain type of cancers such as melanoma was to starve them of arginine. Does anyone know more about this?

 

Hey guys
I'm new and I skimmed through this thread...which has gotten quite long...and there's some great info here. I have ordered all the ingredients for the stack and hope to try it soon.
I realize the ingredients of the stack are taken at 3 separate times during the day, but my question is do you take all of these ingredients together at the same time or space them out?
Thanks!

 

Hey guys
I'm new and I skimmed through this thread...which has gotten quite long...and there's some great info here. I have ordered all the ingredients for the stack and hope to try it soon.
I realize the ingredients of the stack are taken at 3 separate times during the day, but my question is do you take all of these ingredients together at the same time or space them out?
Thanks!

Each of the three stacks are taken at the same time.

 

Each of the three stacks are taken at the same time.

Thanks Gene! Ill let you know how it goes.

 

It's an expensive prospect to hit all that 3x times a day, I'm using just once as a pre-workout. I enjoy it for what I'm using it for but 3x, that's a lot of pills and a lot of moola...

 

Thanks for your post.

 

It's an expensive prospect to hit all that 3x times a day, I'm using just once as a pre-workout. I enjoy it for what I'm using it for but 3x, that's a lot of pills and a lot of moola...

Glad it works for you, Vince

This is just what I do after a lot of research and subjective results.

To this day it does everything I want it to do.

 

Gene,
I am almost 54 years old and think I would have a stroke if I took all of your range stack. Please could you compose a Gene´s light stack for us who don´t lift weights etc... and who are a bit older?

 

Gene,
I am almost 54 years old and think I would have a stroke if I took all of your range stack. Please could you compose a Gene´s light stack for us who don´t lift weights etc... and who are a bit older?

If you go back a few weeks in this thread, you can find my stack which fits your requirements. (With the caveat that the doses work for me and might not work for you.)

Although IIRC Gene is our age.

And BTW, Gene's stack makes stroke less likely. Quote: "The main risk factor for stroke is high blood pressure." Gene's stack is designed to lower blood pressure.

NOTE: Consult your doctor before trying to treat any medical condition, such as high blood pressure.

 

Okedoke I´ll will check. I remember I used to take a lots of supplements like Horny Goat weat etc.. and my blood pressure went trough the roof.

 

According to a quick web search, Horny Goat Weed itself should lower blood pressure. But, some supplements labeled as Horny Goat Weed also add other herbs that might raise blood pressure.

In my view, if you are taking the Tadalafil (generic Cialis) then you can do without the Horny Goat Weed, which is generally used as a less effective, but natural alternative to Tadalafil.

 

Gene,
I am almost 54 years old and think I would have a stroke if I took all of your range stack. Please could you compose a Gene´s light stack for us who don´t lift weights etc... and who are a bit older?

Well, for what it's worth I am 54 as well but lift weights and train hard.

If it were me and I had to pair this down I would stick with the 5 mg of Tadalafil twice daily along with the L-Arginine and L-Citruline.

 

The twice a day 5mg Cialis is really wonderful. Almost wonderful.

 

The twice a day 5mg Cialis is really wonderful. Almost wonderful.

I modified it to 2.5mg and 5.0mg and find it works well. A great stack.

 

Hey, i'm 41 years old, 5'7 145 lbs. I started to lift weights 4 weeks ago and have been training muay thai for over a year. I'm in great shape, lost 20 lbs on the year, probably the best conditioning and musculature in my life.

My baseline for ED of over 10 years is occassional semi to full AM wood, easy loss of wood in sexual situations (condom? forget it), but good sex when I'm rested and turned on.

Recent blood work showed I was deficient in d3, have macrocytosis, 417 total test and 25 SHBG.

I started supplementing 4 weeks ago, when I started lifting, with arginine, creatine, lysine, citrulline malate, d3, b12, hgw, fish oil, cod liver oil, ground flax, korean ginseng and blackstrap molassas... think that's it. I found high doses of arginine (2 tsp) to have definite impact on my 1 hour muay thai classes, giving me strength and energy to excel in sparring and kick pad drills. The creatine has definitely plumped up my muscles. Arginine/Lysine combo before bed has help a bit with sleep, in combination with 3mg melatonin. Melatonin used to give me vivid dreams, but for some reason, not anymore.

About sleep, I don't sleep more than 2 hours at a shot. It's killing me.

I'm not sure, but there was a time popping 2 ginseng and 2 hgw pills in the am was giving me strong morning wood. I'm still experimenting there on dose and which herb is doing what. I'm in the process of making hgw tincture using bulk powder to save on costs, but not knowing iicarin content, it's gonna be a gamble.

A week ago, I started following a short version of Gene's protocol, 3x day 5 g arg/ 2g cit, 3x 500mg 10% hgw, 1x 150mg pine bark. Along with the vitamin/nutrition sups and night time lysine/melatonin. I haven't noticed any improvement on wood. Was hoping for the pine bark to have an effect, but nothing. The HGW hasn't been as effective either. May go back to the Korean Ginseng in a week to see for sure.

I added theanine to my list yesterday, 200mg @ 4pm in the afternoon... I felt it. It felt like a calm blanket came down on my spinning brain. I was able to clear out the pile of old bills, junk mail and paper that had been sitting on my floor for the past week. No anxiety over what was what, what could be tossed, what needs shredding... just sat there and did it. I'm hoping that it will help me sleep better. Didn't take one before bed, was wondering if the first dose would last. It didn't. But, I popped one this morning and I'm here typing out this missive, not going back forth obsessing over proper order or content. Just doing it.

I added 100 mg Hawthorn yesterday as well, I saw it at the store (sprouts farmers market), wasn't too expensive so what the hell. No noticeable effect.

I got my order of liquid cia today, took .16 ml (approx 5mg) this morning. My penis was twitching slightly every now and again where normally, it's just completely dead and quiet.

So today is day 1 of pseudo-Gene's stack. This am:
1 tsp arg
1 gm cit malate
.16 ml liquid cia
3x 150mg@10% HGW
1x 100mg Hawthorne
1x 150mg Pine extract (not pycnogenol brand, just an off "French Maritime Pine etc etc" found on amazon)

Plus:
1x 200mg Theanine
.5 tsp creatine
3x 400 iu D3
2x 1200 mg fish oil
.5 tsp ascorbic acid
2x tiny cod liver caps
2x tiny B12 caps
1x 1g calcium
2 Tbs ground flax

My goals for all these supplements are improvements in ED, fitness/musculature, sleep quality and possibly improvements in skin, hair, vision, stress and overall well being.

 

My baseline for ED of over 10 years is occassional semi to full AM wood, easy loss of wood in sexual situations (condom? forget it), but good sex when I'm rested and turned on.

If you have AM wood, and lose wood easily, then that is excess PDE5 and so a PDE5 inhibitor is needed - either icariin (natural) or tadalafil (pharmaceutical). You have been using both, but I just wanted to point this out.

PDE5 is what, in the normal process, causes wood to go away when it is no longer needed. Apparently aging causes it to increase. If pharma companies know more about this, they ain't telling, because they want to sell more cialis/viagra.

Aging can also affect other parts of the process, which is where citrulline, beets, hawthorn, ginseng, and pycnogenol/gse become helpful.

Which reminds me - I find "Nature's Way Heartcare Hawthorn Extract" to be more effective than any of the others. It is the extract used in the scientific studies on Hawthorn.

 

Thanks for the info.

What noticeable effect do you perceive from the hawthorne?

 

Thanks for the info.

What noticeable effect do you perceive from the hawthorne?

General vasodilation. I have somewhat impaired circulation, so I take supplements to improve it.

Also, hawthorn is said to help the conversion of nitrates (like beets and salad) to nitric oxide (a different pathway from the arginine pathway which is helped by ginseng and pycnogenol or GSE.)