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Hello @madman According to this study, where you give a weekly injection and get a good balance, why do we need to inject the cypionate every day or EOD?
This touches on something interesting we've discussed before: The apparent half-life of the Xyosted product is about 10 days. This is double what's typical for standard formulations of testosterone cypionate and testosterone enanthate. To obtain the relatively steady hormone levels seen with Xyosted you'd need to injection at least twice a week with regular cypionate or enanthate.
Isn't Xyosted testosterone enanthate?
Yes, in sesame oil. Because each dose is pre-contained in an auto-injector there is no preservative. The lack of benzyl alcohol may account for some or all of the slower absorption.
Your free testosterone is up but if you still don't feel well and How low is your shgb .. Have you ever tried less dose of testosterone like 90mg or 80mg?
PMd you!
What was result here? Did you end up taking AI and if so did it help?
Not from experience, but from clinical trials and the basic pharmacokinetics it's clear that total DHT created is about the same whether a testosterone ester is delivered via SC or IM injection. In either case the testosterone is not available for conversion to DHT until after the testosterone ester has been absorbed into the bloodstream, where the ester is cleaved. There can be differences in the rates of absorption, with SC generally slower. Thus SC delivery may produce lower peaks in testosterone, which then also applies to metabolites such as DHT and estradiol.
