shbg

Hi all, new here. I got a reading of 24 for my SHBG on my last reading. Based on that number, what would a good injection frequency be? Am I still in a normal enough range for every 3-3.5 days? Any recommended doses for this SHBG number as well? Thanks.

Just curious to hear some opinions on low ferritin levels having any direct and indirect effects (thyroid function, other) on SHBG.

So I got my 6 week labs and it shows TT at 330, Estradiol at 43, SHBG 16.8 (started at 29 pre TRT) and Free T at just under 10 (they want me at 25 but I would take 15 to be honest). They have me dosed at 140mg Test Cyp weekly however after this lab they bumped me to 200mg weekly. I am doing much...

I have been on TRT since 2011. Initially on a compounded creme (MedQuest) switching later to Axiron and for the past year on testosterone cypionate. I started at the typical dose of 100 mg/week. These labs were drawn to evaluate a dose of 160 mg/wk. I inject IM into my glutes. I am 55. I...

Greetings first time posting. Great forum, any input appreciated. 45 year old healthy male, 4 kids training since 12 years old, intermittent use of testosterone for training since age 35 - no more than 500mgs x 8-12 weeks 4 times over 8 years. Recently off Testosterone as of June 2018 and...

With all the emphasis placed on the importance of SHBG and the free hormones I was wondering what people thought about the article below. Apologies if this has already been posted /discussed. Sex Hormone Binding Globulin: New Science Questions Old Beliefs

SHBG is talked about a lot as a good predictor of how fast one clears testosterone out of their body. Low SHBG frequently necessitates the need for more frequent injections per week. Do factors such as EGFR and hypothyroidism also factor into how fast an individual processes testosterone? On the...

I'm a little confused as to what low SHBG means in terms of dosage. I've seen multiple posts say one of two things 1) Low SHBG means that a lower dosage (<125mg/week) is most likely necessary due to high Free T/ Free E 2) Low SHBG means that a higher dosage (>150mg/week) is necessary because...

Hi all, First time poster. I'm hoping to get some thoughts on my recent blood tests asap as I have an appointment with my doc tomorrow morning so want to be informed and prepared. Blood test results are attached in photos. I've been on trt 6 weeks, had the bloods done on Monday before HCG, T...

The all knowing FDA does not approve of human use. You cannot have it prescribed. I have crazy high SHBG that was stealing most of my free T even on heavy handed TRT. You'll have to do your own homework to find a source that is reliable.

Hi guys my SHBG is consistently in the upper part of the range (e.g. last test: 45.8 nmol/l with a range of 14.5-48.4). What would be a recommended injection frequency? Thx

Hello everyone. I was thinking about how testosterone levels are lower among all age groups for reasons that are difficult to explain and it got me to thinking about shbg. Are shbg values skewed high or low for unknown reasons because the top or bottom of the range can be problematic for some...

Hi everyone, I'm 32 years old and have secondary hypogonadism (was diagnosed at 25 years old). I've been on clomid for around 7 years now that was prescribed by my urologist. My main question is whether testosterone injections are more effective than clomid for secondary sexual characteristics...

My current protocol is injecting 50mg of testosterone every 4 days and 150IU of HCG every 4 days, no AI.. My last blood test came back as follows: TT 764, Free test 14, Estradiol 43, SHBG 46... My issue is that the 1st 2 days after the test injection, I kind of feel like crap. Tired, bags under...

SHBG, low testosterone, and type 2 diabetes. It's frequently said that a low SHBG value is a marker for type 2 diabetes - is that really the case? An Australian study examined prospective associations of SHBG and sex steroid levels in a cohort of community dwelling-men (ages ranging from 35-80)...

Dear forum, My wife is on the way to optimize her hormone levels after long period of inaccurate Levythyroxin medication and the possible damage it did (it went on for few years before she learned about the topic and found a doc that would prescribe Armour). Looking for expert thoughts on the...

Many times the articles, more specifically, the research articles we read relating to all the various components of TRT are not written for the layman to understand. Therefore, I believe a lot of us, myself included, stop reading because trying to self-educate ourselves can be a difficult...

Hi, Age: 44 Physics: slim, muscular, physically active (workout 4-5 times/week). Diet: very healthy Alcohol consumption: normal. 11/6-18: I got blood work done due to depression, fatigue, loss of sex drive, ... [see test/20171116]. 04/01-18 started Testogel. Gels both had an effect on the...

My recent experience with boron. I did blood tests on 1/5/2018, 2/20/2018 and 4/21/2018. The only thing I changed was taking the boron supplement late February. The first month I mixed up my own boron from 20 mule team borax, so I was probably taking 7-10 mg daily, since I would take a...

I read that thyroid meds can increase SHBG. Questions: 1. I have not found definitive info if it is the T4 in the meds or the T3 or both that cause this effect? 2. Is there any info on dose-response of Thryoid on SHBG? I'm being treated for hypogonadism (Cypionate 200mg/weekly +...

I'm 42 yrs old and the last 4 years my energy, strength, and stamina have plummeted. I am generally an athletic/slender guy but my midsection has increased a lot, and I have become very sluggish. My sex drive isn't great so I thought I might take a stab at this TRT stuff&#8230; Here is...

Hello guys. I need some guidance on possibly adjusting my protocol due to high SHBG. Here is my story, I have been on Test Cyp for about 4 months and it has worked very well for me. Started with a low dose of 100mg per week injecting E3.5D, no AI, no HCG. Two months later, on my follow up lab, I...

Hello all and thank you in advance. Little bit of history, I'm a 42yo male, 6'1”, 193lbs and 13% BF. Workout with heavy weights 5 times a week and cardio once per week. I'm on my 6th week of TRT recommended by my doctor for low energy and low libido, poor erections. The doctor found issues with...

Hi everyone, i have too high SHBG. Have you got any ideas how should i deal with it? For last month i was taking 10 000 vit D per day, but felt no changes so since week i take 20 000 vit D per day. Is there any difference if i take vit D once per day or should i take it 2-3 times per day? I...

Does any one have labs that show the SHGB increase after they started more frequent smaller injections? How much did numbers change? Did symptoms you were having dismiss and if so how long did it take for them to dissipate?

So I've done numerous blood tests with similar results. Here are my latest ones: E2: 0.12 (nmol/l) <0.15 [about 33 pg/ml] - Stupid range, but this is actually quite sensitive test Free T: 194 (pmol/l) 155-800 SHBG: 10 (nmol/l) 15-95 T: 8.5 (nmol/l) 8.0-29.0 [about 245 ng/d] These were...

Sex Hormone Binding Globulin levels play a critical role in the success or failure of a TRT protocol. Many men come to Excelmale never having had their SHBG levels checked. In some cases that may be a cost-saving measure, but in far more situations it's simply physician ignorance. Recently the...

I'm a lowish SHBG guy (~19 ref range 19.3-76.4) - started on gels with an endo with limited success and switched to Defy in April. Dr Saya's protocol is subq 44 mg of TestC + 300 IU of HCG 3x/week. Before starting BP normal ~120/83 hematocrit 47.5 (37.5-51.0) Hemoglobin 16.0 (12.6-17.7) PSA...

Have found some information while browsing on this SERM. One of the negative side effects most commonly brought up is that it raises SHBG. However, for those that have low SHBG such as myself..... wondering if this could this be of benefit ? Other benefits are listed as reversing/preventing...

I'm 41 and started TRT Novemeber 2016. Currently on Test. Cyp. (IM) and HCG (SQ) every other day and 25 mg DHEA twice daily (From Defy). I have an appointment in July. Just had blood work and have some questions. Here are the highlights. T total = 932 (up from ~200 pre-TRT, feeling...

Please advise. Just finished first round of Bio T pellets and about to switch to T gel (20%) next week to get a steady consistent dose. My dilemma is my high SHBG levels. Total T: 646 SHBG: 77.4 Free T: 7.6 Two part question. Will lowering SHBG level increase Free T, and is there a...