shbg

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  1. H

    Help fine tuning my protocol

    I have been on TRT for almost one year now and I am trying to keep my Total Testosterone around 1100-1150 ng/dl. Protocol and bloodwork results below: Testosterone cypionate 200mg/ml 0.35ml 2x a week. HCG 400IU 2x week TT 1331 ng/dl FT 35.6 pg/ml SHBG 25.3 nmol/L Testosterone cypionate...
  2. J

    SHBG: Does it just bind and render androgens useless or does it have a purpose?

    SHBG is mentioned a LOT on this forum, and often many men are unhappy with their levels. Very few comments regarding SHBG are positive in nature, in fact SHBG is seen as a problem by many, and in the steroid community it is seen as something that needs to be lowered otherwise it'll "steal" all...
  3. Y

    35 with high SHBG, libido and erection issues. Labs inside, should I call defy?

    Hello, I've had libido and erection issues off and on for at least five years. During the same time frame I've also experienced periods of melancholy mood. I have a bit of anxiety but I've not needed medication. My sex drive and erection quality have both taken a huge dive over the past 12...
  4. D

    High insulin-high glucose? Low SHGB

    Hello guys, I've been on TRT for about a year now. After a lot of trial and error I found a protoclo that works for me and it's 140 mg Test E split into 2 doses 1.25 mg arimidex per week This puts me at around 1.000 ng/dl and keeps my e2 low. Now my SHGB is 21 which falls into the normal range...
  5. Q

    TRT Dose for low SHBG?

    Hey guys I have low Shbg 15-18nmol/l pre-trt I wonder if low shbg should stick to a lower trt dose? Like 80-100mg/week, if I'm correct low SHBG Leads to easier elevated estrogen? As I feel some lump and strings under my chest mass if I grab hard and feel I am currently on 150mg/week split on...
  6. Nelson Vergel

    Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans

    Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans Andreas Peter1, Konstantinos Kantartzis1, Jürgen Machann2, Fritz Schick2, Harald Staiger1, Fausto Machicao1, Erwin Schleicher1, Andreas Fritsche1, Hans-Ulrich Häring1 and Norbert Stefan1 1Department of...
  7. Nelson Vergel

    Alzheimer's Patients Have High SHBG

    Xu J, Xia LL, Song N, Chen SD, Wang G. Testosterone, Estradiol, and Sex Hormone-Binding Globulin in Alzheimer's Disease: A Meta-Analysis.Curr Alzheimer Res...
  8. S

    High SHBG and low insulin

    Hello, guys! Do you have any ideas how to low SHBG and what is the reason in my case? I have no any problems with liver (good tests), alcohol etc. May be the reason is my low insulin, but my sugar is also in normal range. My last results: - testosterone 14.81 nmol/l (ref 10,4-37) - SHBG...
  9. Nelson Vergel

    Anabolic steroids and TRT decrease SHBG, DHEA, pregnenolone and progesterone in men.

    Response of serum testosterone and its precursor steroids, SHBG and CBG to anabolic steroid and testosterone self-administration in man. Ruokonen A, et al. J Steroid Biochem. 1985. Abstract The influence of high doses of testosterone and anabolic steroids on testicular endocrine function...
  10. H

    High Free Testosterone level concerns?

    What concerns are there for having high Free Testosterone scores above the normal limits after two months of TRT when Total T, Estradiol, Hematocrit levels are all as expected? What are the next tests to consider if any?
  11. Nelson Vergel

    How to lower your sex hormone binding globulin

    This is part II of: Role of Estradiol and Sex Hormone Binding Globulin in Men HOW TO TREAT ELEVATED SHBG 1.Remove any of the agents or treat the condition, which lead to elevated SHBG. In some cases it may be difficult to identify the cause of elevated SHBG. 2.Use anti-aromatase meds such...
  12. Nelson Vergel

    Role of Estradiol and Sex Hormone Binding Globulin in Men

    Published in Olympian News Magazine - 2010 PART I It has been traditionally thought and believed that sex hormone binding globulin (SHBG) is more or less correlated to estradiol (E) levels and the amount of free testosterone (FT). Free - testosterone is the portion of testosterone (T)...
  13. Nelson Vergel

    Sex Hormone Binding Globulin and Estradiol Management - by Dr K. Kullis

    It has been traditionally thought and believed that sex hormone binding globulin (SHBG) is more or less correlated to estradiol (E) levels and the amount of free testosterone (FT). Free - testosterone is the portion of testosterone (T) that is available to enter a cell and bind to the androgen...
  14. Nelson Vergel

    How to decrease SHBG and increase free testosterone

    As shown in the figure above, about 2 percent of the testosterone in the body is active. This “free testosterone” is not attached to binding proteins that would prevent it from interacting with its receptor. About 40 percent of the body's testosterone is attached to albumin. This is a protein...
  15. D

    SHBG: who has successfully lowered their levels?

    Feedback please from individuals that have lowered SHBG and what their protocol is/was. I've searched and found: estrogen/AI medication, danazol, stinging nettle and milk thistle quoted, but I would like to see more applied examples to avoid unnecessary supplements and medication. Thanks!
  16. flexing37

    Need help - high fsh anb lh (testosterone keeps rising)

    Last April in 2013, I started having sensitivity in the Left nipple area and got some blood work done. Ended up getting a Biopsy of the nipple area and was diagnosed with Gyno. Then had a Biopsy done as well with negative results for any tumor. Then had an MRI of the brain done in July...
  17. Nelson Vergel

    Higher Sex Hormone Binding Globulin Linked to Better Heart Health

    Serum Sex Hormone-Binding Globulin and Testosterone In Relation To Cardiovascular Disease Risk Factors Canoy D, Barber TM, Pouta A, et al. European Journal of Endocrinology. http://www.eje-online.org/content/early/2014/03/26/EJE-13-1046.abstract Objective: Reduced sex hormone-binding...
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