shbg

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  1. A

    Will a 20mg bump decrease SHBG?

    I’m currently injecting 80mg once a week but I’m increasing my dose to 100mg. My current SHBG is 23 but I’m concerned this increase will lower it? What do you guys think?
  2. D

    DHEA Supplementation Effect SHBG?

    Hey guys, I recently began supplementing with a low dosage of micronized DHEA(10mg daily) to see if I can boost my lower levels. I ran 25mg a day at one point in the past with a cheap version and it caused some estrogen related side effects which I was trying to avoid with a better quality...
  3. J

    Full lab results (update)

    Thanks for taking the time. This is a follow up to my thread from last week (Total T > 1000 ng/dl (very high), Free T < 65 pg/ml (very low)). Total and Free same deal as last time, and not surprisingly SHBG is super high. Is there anything else in there I should pay attention to? I'm 40yo, in...
  4. M

    New bloods

    VA didn't have a Dr for me at local clinic, result I got a bunch of test done! I was really struggling with a T dose of 200mg split daily and in anticipation of new bloods I lowered dose to 150mg a week for one week and then to 140mg a week, a game I have to play so VA wont cut my dose. However...
  5. K

    Injection frequency & SHBG levels

    Hey TRT fellows, I’m still struggling to get the best out of my trt journey and have a question that I can’t seem to find a definitive answer for: Is a SHBG of 24.2 nmol/L considered low ? And Would u go with an ED or EOD protocol with a SHBG level similar to mine ? Thank you
  6. M

    boron for SHBG

    Has anyone been successful in decreasing SHBG level by using boron supplement without TRT?if YES, please give details
  7. A

    Minimum Dosage or freq for low SHBG

    Hi Everyone, I was wondering if anyone were able to decrease or stop the aromatization of testosterone without the use of AI. If yes, what would be the minimum dosage we need? Does daily injection reduces aromatization? Its hard to find proper dosage for people with low SHBG and they end up...
  8. B

    Interesting findings regarding my low SHBG after adding NDT when reviewing old labs....

    From my many posts on this forum many people probably know by now that I am a Low SHBG guy (8-18 labcrop range) which manifested after starting TRT 10 yrs ago... I have never gotten dialed in despite numerous changes in Test dosage, injections, etc... It's been a struggle to lose weight despite...
  9. B

    TRT induced Low SHBG and TRT dosage?

    Ok, I just read through the entire Low SHBG sticky thread and have been researching all over this forum regarding low SHBG and Trt dosing... I was able to pull a lab test from 12 years ago prior to starting TRT and I had a SHBG of 44 (lab corp range)... Since starting TRT my SHBG has dropped...
  10. B

    Novel insights in SHBG regulation and clinical implications

    Sex hormone-binding globulin (SHBG) is produced and secreted by the liver into the bloodstream where it binds sex steroids and regulates their bioavailability. Traditionally, body mass index (BMI) was thought to be the major determinant of SHBG concentrations and hyperinsulinemia the main cause...
  11. S

    What could cause decreasing TT on increasing T doses?

    I've had an issue for the last couple of months now where my TT has not been nearly as high as it used to be given a particular dose of T cyp. Early Feb I saw a 600 off 150mg/week. Last week, 730 off of 182mg/week + 150IU HCG EOD. Last fall, I was at 1200 with 200mg/week. Where the hell could...
  12. D

    Nandrolone (Deca Durabolin): Effect on Lab Tests

    PARTICIPATION NEEDED! Of those EM members that have taken nandrolone or are currently taking nandrolone alongside their TRT, we are conducting a small ExcelMale study to help determine the effect that nandrolone has on Total Testosterone, E2, Prolactin, SHBG, free T, and DHT while taking TRT...
  13. V

    How long for TRT to reduce high SHBG?

    I know that most TRT places recommend 3-6 months for TRT to show results for low total T. My case may be different, as I have a test of 700 due to a high SHBG of 66. These were my baselines before starting Natesto. I’ve been on Natesto for 2 months, and I can’t really tell if it’s helping. I...
  14. T

    Low SHBG, Strength, EOD, etc

    Gents, I’d love to get some input on this. I’ve started TRT 3 months ago. 43, fairly healthy, lifting 4 times a week. Baseline: BP 120/72 TT 275 (264-916) FT 12.5 (6.8-21.5) E2, SENSITIVE 10.6 (8-35) SHBG 25.7 (16.5-55.9) HCT 45.1 (37.5-51) TRIGLYCERIDES 117 (0-149) HDL 35 (39- ?) LDL...
  15. R

    Low SHBG Success Story - Almost 4 Years of TRT

    I know there are many low SHBG posts and most are negative for the most part. I wanted to share some things that I have learned through some experimentation over the last 4 years seeking more libido that have helped me dial some things in to my current protocol: 19mg T-Proprionate ED .25mg AI...
  16. B

    Some aromatize a lot or a little?

    Some threads state some folks "aromatize a lot" or "aromatize a little". What does this mean? Is it related to SHBG?
  17. M

    scrotal cream for high SHBG guys?

    Hi everyone, I’m thinking of giving the scrotal cream a try after almost a year of injections and limited success with varying protocols. I’m wondering if there are any high shbg guys like myself that have tried the cream and what has been your experience? My shbg pre-trt was between 55-70. On...
  18. S

    Weird drop in SHBG leads to sudden E2 issue.

    I have been on TRT for 2.5 years and have had textbook levels - TT around 1000, FT in the 20's, SHBG fluctuates between 45-50 and E2 typically matches SHBG. I have never had any E2 symptoms though I will admit that my regimen would create an E2 nightmare for most - test cyp 60 mg every 3.5, HCG...
  19. T

    SHBG level inversely related to insulin level

    I haven't seen this mentioned previously. This suggests that those who are struggling with low SHBG should test for hyperinsulineamia. The relationship between serum levels of insulin and sex hormone-binding globulin in men: the effect of weight loss. As SHBG is not known to alter the...
  20. K

    How to lower IGF 1 ?

    Is there a proven way or supplement for lowering IGF1 ? Besides the internet BS regarding diet .
  21. D

    Is it true there is no cure for post accutane?

    Hi, I have low SHBG, and have been on TRT for the past 5 years with very low success. If I feel good with energy and libido it is for a few hours/days, and then it fades. Since I have low SHBG, that was my first suspect, but after reading about post FPS and Accutane, I am afraid my issue is due...
  22. D

    E2 levels for low SHBG guys (0-15)?

    Hi All, Can low SHBG guys comment on what is your protocol? and Whether it works successfully for libido and energy? - From what I have read and in my personal case, when E2 is low, mirroring SHBG values, it is like the sweet spot, and rationale is that the low SHBG makes too much of free E2...
  23. S

    Low SHBG guys. Will increasing injection frequency make any difference?

    Has anyone with low SHBG increased their injection frequency (say from 2x a week to every other day or daily) and found yourself feeling better?
  24. M

    Just started TRT

    Hi all, from the uk. 34 years old. starting TRT due to lifelong ED, and only weird thing in my bloodwork is over the range SHBG 60 ( 5-55 ) everything else is fine. I need caverject to perform, so I'm starting TRT to see if low free test is my issue. I injected 125mg on Sunday night few...
  25. K

    High testosterone and High ShBG with low sex drive.

    Just got approved TRT because of my tricky SHBG. Would love some advice on this subject.
  26. N

    For those with high SHBG.

    I managed to cut my SHBG in half over 6 months by taking 9mg Boron Daily and an increase of 40mg of testosterone weekly. great free T increase as well!
  27. B

    High SHBG and larger, first TRT dose >100mg?

    Seems the standard protocol for TRT is to start at 100mg Test C per week. Should one consider a higher starting dose if they are: 1.) Larger (in my case 6'3", 200lbs, <10%bf) 2.) Have low total T of which a very high amount is SHBG My last test results are: Total test: 499 ng/dL SHBG: 55.1...
  28. A

    SHBG is there an ideal level?

    When I first started TRT may doctor at the time said that we needed to get my SHBG down as it was at 60. Sure enough TRT reduced it to 35. It crept up again as I was put on a lower T dose to try and reduce aromatisation ednding up at the start of this year at 48 - at the same time my Total T...
  29. falconberg

    Low SHBG and Estradiol

    I've been on TRT since May 2016. I'm currently on a three-month break to reassess some things and am trying to educate myself so that I can hopefully have better results if I have to get back on (which is looking increasingly likely). I have low SHBG (currently around 18 NMOL/L, but as low as...
  30. Charliebizz

    Shbg and transdermals.

    I’m a low shbg guy and was a patient of dr crislers for years we tried everything we could for my low t levels except transdermals. Currently I’m at 211 total t. I have low shbg. 12-15. I did horrible on all kinds of injection protocols. I stayed away from gel because of small child and another...
  31. D

    Only when E2 is super low I feel good

    Hi, I am a low SHBG guy who has managed to increased it to around 14-15 while on TRT. It has been years trying to fine tune my protocol and after several lab tests and anaztrozole dosing, I have confirmed I feel best when my E2 is around 10ish. At that level my libido is very good, no bloating...
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