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Here it is: https://www.excelmale.com/threads/blood-donation-and-aging.30635/

Many people in the anti-aging world have heard of the experiments done by the team of Mike and Irina Conboy which involved putting the blood from young mice into old mice and vice versa. In summary it showed that the old mice showed signs of getting younger and the young mice showed signs of...

I'll do a post in the Anti-aging section when I have a chance so everyone can see it

I actually heard that from other people so I don't know what his view is. I think from a post of his several weeks ago that he looks at a variety of things including other related minerals such as copper and manganese, but it's certainly not to rely on ferritin. But the bottom line is that is...

While I agree that your doc may be a bit over-aggressive on Hematocrit, Iron overload is certainly not something you want and my understanding is that TIBC is one of the best measures of that. Donating blood is one of the only ways (for men) to get iron out of the cells. You may have some sort...

search for the thread "infrequent dosing to avoid shutdown". Short answer is 1) use the term suppression , not shutdown 2) some oral protocols in combination with a SERM appear to minimize suppression 3) Test E is is likely not a good choice for this purpose 4) use of a SERM like clomid or...

While waiting for your copy of The Clot Thickens to arrive, here is a video summary with the author. He covers a lot in a short time and a lot of it is covered in much more detail in his What Causes Heart Disease blog which the book grew out of, but this will get you started. It also reminded me...

You want to do things that increase insulin sensitivity and avoid things that spike blood sugar (there is a compelling school of thought that extreme spikes in blood sugar may be worse than the average level, as long as the average level is not high.) So specific steps could include: - eat...

Note that low A1c is only good if fasting insulin is also low, such as 6 or below. Having high insulin to keep blood sugar down only replaces one problem with another (possibly worse) problem.

Perhaps E2 and Nandrolone (for those who tolerate it, maybe boldenone for others) is what Pca patients should really be getting (ignoring Dr. Samuel Denmeade's high testosterone approach.) That might maintain almost everything needed to prevent deprivation issues.

You might try a low dose of zinc for your E2. As someone with low E2, it turns out that a lot of things inhibit aromatase and zinc is one of them. Melatonin may help as well.

Some of Noel Creek's products may give you what you are looking for and they sell online

There was no discussion in the study about interaction with symptoms. I find it hard to believe that if supplementing thyroid relieved symptoms typical of low thyroid such as lethargy, excess fat, depression, CVD risk etc. that that wouldn't result in longer life, or at least a happier life of...

It sounds like a lower dose is really what you need.

This is a huge book-length topic but here are a few quick thoughts: - Read the book Perfect Health Diet (and look a the website for the book as well) and follow the supplement recommendations - There is another mega-thread here with supplements in general - At a minimum, I would add glycine to...

I have been taking it consistently at a low dose, but again, you will need to experiment. I have not had any side effects I can detect.

Here is a recent post from AMidwesternDoctor on sleep. He doesn't include blood-sugar swings which I think is an underappreciated issue, but a lot of good info here...

It seems to for me, but I think it will differ by person since some people react negatively to it. You will likely have to give it a try and see how you react. I would start at a low dose like 12mg every other day of 25 mg twice per week.

If you're just waking up then for seemingly no reason, that screams low blood sugar episode, so you might want to focus your research on that. Some people find that spoonful of honey before bed is helpful for that, although that is more of a band-aid that a fix, but it might help to confirm what...

Avoiding things which cause poor sleep such as blue light exposure in the evenings, stimulants, overtraining and excessive alcohol are the place to start. Low blood sugar episodes (which IIRC cause a cortisol spike) will also cause episodes of waking in the middle of the night and need to be...

Magnesium and CoQ10 can also help EF

I think the point is that supplementing T while maintaining some degree of natural production is likely possible. Figuring out a sustainable protocol will require more crowdsourcing, but I would want to at least try this route if I was starting down the TRT road again.

A few thoughts: Even small amounts if taken without the correct co-factors (K2, A and E) especially K2 could be "too much" but the problem is the lack of K2. An amount that puts your blood levels between 50-80 seems to be the optimal range from what I remember. When I'm not getting much sun, I...

Fluoride in the water supply could also be considered an Endocrine Disruptor given its damage to the thyroid. A table-top water filter is fairly cheap and seems like an essential health aid.

I too have stopped taking it consistently and only take it if I have a cold, which I almost never do. It's worth stepping back and considering the general guideline that it is best to wait about 5 years after a compound/drug is released before making a judgment on it's risk/reward. I think...

Hopefully he will give us an update no matter how it's going, however your negativity is not helpful. There is a lot we have to learn and overconfidence about what we may think does or does not work, especially for a given individual, is an obstacle for experimentation and learning.

It's referring to the chemicals which create things you've certainly heard of such as performance anxiety and sympathetic nervous system activation. I think one of the components of Trimix is an alpha-1? blocker which basically IIRC blocks the local action of norepinephrine, which creates the...

This sounds like the result of a change in Adrenergic tone, and if N is having and anti-anxiety affect, (or perhaps something like the uro-specific alpha blockers) that would explain a lot of the erection benefit. If you search on "ultimate adrenergic control of erections" you should find a...

This reminds me of a thread from maybe 6 months ago where someone got great results from injecting every three weeks IIRC. Just because we don't know exactly how it works doesn't mean there might not be something to this approach, so thanks to OP for posting his experience. This is what...

I am, but OP will likely have bloodwork much sooner. I have added some Clomid into my TRT and I will be interested to see what my LH is, but so far it seems to replace HCG very well. My main point here is that I wish I had started with a Clomid+ protocol before I started full TRT, and I think a...

40% is nowhere close to "shutdown" "All androgens or SARMS will shut you down, fast and in very small doses." The study you quoted in your first sentence directly contradicts this. Somewhat off topic, but 15mg for 5 days is IME an unnecessarily high dose to at least get a strength boost. I...