I agree GA,
Labs are important but only take a snapshot from one moment in time as estrogen fluctuates.
For me erectile strength (morning wood) is the best indication of where my e2 is at.
I'm on 100mg twice a week and .25mg anastrozole 24-36 hours post injection.
The worst part about the Adex is cutting those pills... never exact... nor is the liquid dosing.
I was running 50eod for a while TT was 1270... Free t thru the roof... e2 37... but still didn't feel great. E2 was too high despite a good ratio.
I'm very sensitive to estrogen and very sensitive to anastrozole. Sometimes a very difficult balancing act... still way better than pre-TRT.
I feel best when e2 is high teens believe it or not.
I am low shbg.
Bonetti,
So what do you do?
Low shbg guys have had success with more frequent injections... but (for me) does not eliminate the need for AI.
The most success I have had is a steady t protocol and gauge e2 by morning wood then come close to establishing a protocol although it always varies and cutting those pills sucks.
For my low SHBG im trying an E2 in the <20 range, I was using .25mg/EOD that took me to the teens and we thought that that was too low so we went .25 M/W/F, but we didn't take in to account some of this new(er) info about low SHBG and Free Estrogen that goes along with High Free T that we low SHBG guys have. SO it's something that is a newer viewpoint for the low SHBG crowd.
Vince
please explain this Free Estrogen and Free Testosterone relationship with low SHBG guys, cause I did noticed doing better with my E2 on the low side, like around 25, is that free Estrogen binds to FT giving us a false high FT reading??
Vince what is your T protocol to go along with that AI dosing?