Why All Men Should be Tested with the Sensitive Estradiol Test

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How less accurate exactly? Two months ago I had a 19 on the 140244 test.

Nelson, you might want to chime in....

I dont know why 140244 is less accurate than 500108. I am going off of Nelson's experience with dealing with labcorp.

I've had 140244 myself.

140244 gave me a result of 37 pg/ml while the normal estradiol gave me a 66.9 pg/ml. Both results were for the same collection sample.

Go figure!
 
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And that's why the sensitive is more accurate than the standard. One is a little high, the other is basically off the charts. I know the difference in mine 19/32 isn't far off from being double the difference. I'm sure if I hadn't taken the wheel my provider would have suggested even more Anastrozole than the .25mg EOD I was on. I was nearly crashed on low E2 and would have continued treating HIGH E2. Go figure.
 
Nelson, you might want to chime in....

I dont know why 140244 is less accurate than 500108. I am going off of Nelson's experience with dealing with labcorp.

I've had 140244 myself.

140244 gave me a result of 37 pg/ml while the normal estradiol gave me a 66.9 pg/ml. Both results were for the same collection sample.

Go figure!

Interesting, I am also using 140244 succesfully.

..
 
I was able to find the right estradiol blood test based on mass spectrometry/liquid chromatography:

Affordable ultrasensitive estradiol test

Definitely affordable! The test description states:

The commonly used estradiol test may overestimate estradiol. That test uses immunoassay technology that cannot differentiate C-Reactive Protein (involved in inflammation) from estradiol, so it reads the combination of the two as estradiol. This ultra-sensitive estradiol test is based on liquid chromatography/mass spectrometry (LC/MS), an assay technology that does not have that limitation.

What test is it referencing ("commonly used estradiol test"), the standard or the sensitive?
 
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The regular estradiol test is based on immunoassay ECLIA technology. The one offered by DiscountedLabs.com is the sensitive one that uses mass spectrometry/liquid chromatography (MS/LC). MS/LC has no interference from C-reactive protein. Immunoassay-based estradiol tests tend to overestimate estradiol since they "see" C-reactive protein as estradiol. My concern is that men are basing their decision to take anastrozole based on a test that is over estimating their estradiol value. This results in over treatment or treatment that may not be needed. Estradiol is important for men's health!
 
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I was able to find the right estradiol blood test based on mass spectrometry/liquid chromatography:

Affordable ultrasensitive estradiol test

Thank you so much for this information Nelson. My estrogen got out of control when I stopped my ai for awhile and I've been trying to get it back in line. I was using aromasin and my estrogen came back a 7.5pg/ml on a scale of 7.6-42.6 pg/ml. Stopped my aromasin and three weeks later I was 494 on a scale of 40-115 pg/ml. I have switched to arimidex (that's all they will prescribe me now) at .5mgs a day for three weeks and feel better, but I can't get rid of the face bloat and my eyes are puffy. I wanted to try adex because it seems like estrogen comes back faster if you drop it too low, but I am so tired of trying to find the right dosage. I was going to do .5mgs adex for three weeks to a month and then switch to 1mg a week in split doses and see if that kept in under control. I just don't know how long this adex dosage will take to get things under control. I'm going to get a blood test tomorrow and see where estrogen is at.
 
just wanted to say this thread has some good info, thanks for sharing. I am going through the same stuff right now. First E was in range and next time it's over range. Dr. put me on .5mg a day yesterday. I do have symptoms of high E but I'm not even on hrt yet.
 
just wanted to say this thread has some good info, thanks for sharing. I am going through the same stuff right now. First E was in range and next time it's over range. Dr. put me on .5mg a day yesterday. I do have symptoms of high E but I'm not even on hrt yet.

that is an OVERDOSE... .5mg PER DAY...you need to not do that and then consider the treatment this Dr is providing you.
 
i knew he didnt know what i was asking cause of the look he gave me,i asked cause i though my e2 was low as i had good erections but dull ejaculation and no libido
 
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