I was diagnosed with moderate hypothyroidism and Hashimoto’s through
Defy and started meds 3 years ago. (And a big thanks to them because every other doctor I saw was basically telling me to do nothing until my thyroid was pretty much destroyed and only then will they put me on medication).
My TSH was around 4 with a FT3 in the mid range (2.6) and midrange FT4.
I started out on Armour Thyroid but it actually made me feel worse and the reason was I was not converting the T4 into the active thyroid hormone, T3. This can be determined by looking at reverse T3 - mine was of the charts when I started Armor with very little change to FT3
I switched to Liothyronine (which is generic cytomel - T3 mono therapy) starting at 10 mcgs / day and slowly titrating up to 20. (4 pills taken throughout the day).
It has made a world of difference for me and alleviating brain fog, and also helping with metabolism. I can pretty much eat anything and not gain weight. Not kidding. The only drawback is that occasionally T3 will build up in my system that every few months I start getting some anxiety and insomnia at night, in which case I just back off one dose for about a week and then resume