Testosterone with Anastrazole

Chris Morrow · Nov 5, 2013

Has anyone used Testosterone injectable compounded with Anastrazole? If so what was your experience like? What was the dosage? I have a formula with 200mg Cypionate with 1mg Anastrazole. I am about to try it out but wanted to see if anyone had more experience.

Nelson Vergel · Nov 5, 2013

I am 100 percent sure that injecting 1 mg per week of anastrozole will plummet your extradiol to low levels, which is not a smart thing to do. I formulated a gel containing testosterone and anastrozole and was shocked about how well anastrozole absorbed.

Here is a patch study which I used to calculate transdermal absorption http://www.sciencedirect.com/science/article/pii/S037851731000133X

Of course, you can do your own experiment by measuring total testosterone, estradiol, etc at baseline and then 7 days after the first and second injection to see. But my gut tells me 1 mg IM will be too much.

Chris Morrow · Nov 5, 2013

I had the same feelings about estradiol going to 0. It is the PCCA's formula that they provided to our pharmacy. Generally, the PCCA wouldn't have a formula that they spent thousands to create if it hadn't been tried before. I just can't find someone who has tried it. So I think I may end up being the guinea pig.