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I haven’t dug too deep into Natesto, or Jatenzo, but from my understanding, both preserve fertility better than longer ester preparations of test, like test cyp/ enanthate. I assume this is due to their very short half lives, and therefore less HPTA suppression
On this theme, I started doing some social media moderation work for Maximus, and what they are doing with oral testosterone together with enclomiphene will blow your mind. In their clinical research, the higher dosed group reached peak total T levels of 1327 ng/dL on average and peak free T of 383 pg/mL (38.3 ng/dL) while maintaining full HPTA function. Their LH and FSH were actually higher post-treatment than baseline. Kind of makes you rethink what is possible here.

 
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On this theme, I started doing some social media moderation work for Maximus, and what they are doing with oral testosterone together with enclomiphene will blow your mind. In their clinical research, the higher dosed group reached peak total T levels of 1327 ng/dL on average and peak free T of 383 pg/mL (38.3 ng/dL) while maintaining full HPTA function. Their LH and FSH were actually higher post-treatment than baseline. Kind of makes you rethink what is possible here.

Holy sh*t, this is wild stuff! From everything I’ve been seeing the past few years, I definitely think maintaining either a fully functioning HPTA, or having a very minimally suppressed HPTA, while concurrently on exogenous means to maintain healthy testosterone levels, is the future of TRT/ HRT. Which is amazing news for anyone with sub optimal testosterone levels, all across the world, and all the people in the future that will end up dealing with this issue
 
Latest labs using Natesto between 4 and 5 months now.
Not feeling great at all and my sex drive is in the dirt.
I stopped Natesto yesterday ( Saturday 15 June ) and see my Uro tomorrow.
I don't expect much help there but hopefully he'll get my Defy Entrace exam sheet filled out so I can move forward which will be trying Propionate.
 

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Latest labs using Natesto between 4 and 5 months now.
Not feeling great at all and my sex drive is in the dirt.
I stopped Natesto yesterday ( Saturday 15 June ) and see my Uro tomorrow.
I don't expect much help there but hopefully he'll get my Defy Entrace exam sheet filled out so I can move forward which will be trying Propionate.
When was the blood draw in relation to dosing? As far as application, do you paint it on with the applicator or do you follow the insert instructions: dispense and gently massage?

Looks similar to the results I’ve gotten. I’ve never pulled anything higher than a 470 ng/dl and I’ve pulled labs within 30-60 min.

Application-wise, I’ve persisted in painting it on to prevent the gel from ending up in the back of my throat or running out of my nose. Technically, I haven’t been following the dosing instructions. Been thinking about that lately and wondering if absorption would be better with blobs of gel (testosterone and gel matrix) sitting in my nose… the result of following the instructions vs. being too smart for my own good and painting on a thin layer with the applicator to prevent the annoyances that come from dosing as instructed.

Guy on Reddit just posted his labs 1 hour after dosing and pulled a 770. He said he applies per the instructions: dispenses and gently massages the nostrils.
 
I have been pInting on as I was getting to much down the throat and a little burning g in the gut.
Blood draw about 1.5 hours after application.
My total t has on moved about 20 poi ts since last time.
My shbg is a little high but Lwzys has been.
I've tried several things to get it down but it won't move.
 
I have been pInting on as I was getting to much down the throat and a little burning g in the gut.
Blood draw about 1.5 hours after application.
My total t has on moved about 20 poi ts since last time.
My shbg is a little high but Lwzys has been.
I've tried several things to get it down but it won't move.
It may be worth experimenting with dosing per the instructions. Clearly it’s possible for some to see a substantial peak 1 hour after dosing as evidenced by the trial data.

As for SHBG, not sure what your diet is like but low carb diets/fasting tends to raise SHBG.

On paper, I still believe Natesto is a superior form of TRT especially given the prospect of preserving HPTA function.
 
Thanks for the reply.
I may give another chance as I've only stopped for one day.
I am interested in TPsp I may give it a 90 day trial to see how I feel.
It's all an experiment at this point to see where I feel and get the best.....
 
Thanks for the reply.
I may give another chance as I've only stopped for one day.
I am interested in TPsp I may give it a 90 day trial to see how I feel.
It's all an experiment at this point to see where I feel and get the best.....
Happy to dialog with a fellow Natesto-er. One thing to keep in mind as you chew on next steps. Judging from your LH/FSH, you’re currently not suppressed and recovering from suppression can take some time as I’m sure you’re aware. I believe a fully functioning HPTA is critical if you hope to have success on Natesto. Every time I’ve gotten back on Natesto following the use of a T ester and thus substantial suppression, the subjective benefits just haven’t been the same as opposed to starting Natesto following a period of zero suppression with a fully functioning (lackluster… yes) axis.
 
Yes I agree. I'll start back for another round to see what improves.
I've got to do something about my drive and my ed.
My wife of 47 years is on fire and I'm floundering like no tomorrow.
Not good.
I'm investigating but I'll tell u most doctors are not good with ed. Take a pill and everything should be ok.
 
Yes I agree. I'll start back for another round to see what improves.
I've got to do something about my drive and my ed.
My wife of 47 years is on fire and I'm floundering like no tomorrow.
Not good.
I'm investigating but I'll tell u most doctors are not good with ed. Take a pill and everything should be ok.
Bi-Mix or Tri-Mix will guaranteed solve this problem immediately. If you are going to wait for the right TRT protocol to fix your erections, you and your wife might be waiting a long time.
 
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