None of the protocols I listed. At the most, I'd have a momentary improvement and, like a moving target, it would disappear. My focus, now, is on thyroid. My urologist came to suspect that there might be central hypothyroidism or cellular thyroid resistance, since I'd gained 35 pounds over several years, was chronically depressed and of course, erectile dysfunction. Next week I have a virtual consult with a psychiatrist whose work is focused on thyroid and mood disorders. I have treatment resistant bipolar illness. 15 years of treatment failures. This might be the last hope for me.