Should I continue trt or not?

[ratt57]

I'm 68 and have been on trt for about six months now (100 mgs. injected bi-weekly) and the changes I've experienced have been pretty profound. My libido came back, as well as erections and even semen volume. I'm building muscle at the gym and just generally feel better emotionally.

I had a full-body PET scan for lung cancer at the end of 2024 and the scan showed some unexpected metabolic activity around the prostate. I then had a prostate MRI done and the report states that there appears to be a nodule on my prostate which the radiologist who read it seems convinced looks like T2 cancer. I'm now waiting for (and dreading) a prostate biopsy. The strange thing about all this is that my PSA has always been incredibly low. When I started trt it went from 0.324 to 0.635 and hasn't risen any further. I also have no history of prostate cancer in my family.

I'm hoping, of course, that this biopsy turns out to be benign or even inflammation possibly caused by the testosterone, or maybe that's just wishful thinking. Right now I don't know if I should continue my bi-weekly dose or not... I keep getting mixed messages. There are medical papers all over the internet stating there is no correlation between trt and prostate cancer, but then my urologist assistant tells me there is.

I don't know if anyone else has been in this situation, but any advice re: whether I should continue or not would be appreciated. I didn't dose yesterday because I'm afraid to do it, but I also don't want to lose the gains I've made.

 

[Systemlord]

You're at no greater risk of prostate cancer than someone with naturally high testosterone, being on TRT doesn't increase risks, it only decreases risks.

If you go based off the available evidence below, more than likely, it’s a benign growth.

A prostate MRI is more accurate and the new gold standard for prostate cancer screening.

Prostate biopsies are inherently inaccurate and evasive and has the potential to cause more harm. Too bad your doctor isn’t up-to-date.

 

[Systemlord]

Thread 'Impact of Low Free Testosterone on Prostate Cancer'

Oct 9, 2022

• madman
• testosterone replacement; prostate cancer; free t
• Replies: 13
• Forum: Prostate Related Issues

https://www.urology.uci.edu/pdf/The_Impact_of_Low_Free_Testosterone_on_Prostate_Cancer_High_Risk_Disease_Recurrence_and_Testosterone_Replacement_after_Radical_Prostatectomy.pdf

Thread 'TRT does not increase cancer risk in men treated for prostate cancer'

Oct 3, 2023

The prostate is a gland that attracts great attention in men’s health. One of the major issues is related to cancer. Prostate cancer is one of the leading causes of death in men in the United States. As men age, small hidden prostatic lesions become increasingly common. These may or may not become cancerous. These lesions occur in 30 percent of American men over the age of 45, with the prevalence rising to more than 80 percent for men over the age of 80. Genetic factors and lifestyle conditions such as diet are believed to contribute to this transformation.

Doctors use different...

• Nelson Vergel
• Replies: 0
• Forum: Blood Test Discussion

 

[Seagal]

Do you have lab values of your testosterone and estradiol? I would keep the testosterone level in healthy normal range, i.e. probably less than 200mg per week, rather 100mg or even less.