If you are a little "itchy" get a CBC blood test done to look at your hematocrit and hemoglobin. If they are increasing, that can explain the itchiness. As they rise in value, and you will see other red blood cell parameters getting out of the normal ranges as well, you liver and gall bladder have to produce more bile specifically bilirubin, to help handle the breakdown of all the additional red blood cells and hematocrit and hemoglobin. It an even turn your poop a little yellow. if your eyes get a little yellow, or you skin, then you have a problem. Otherwise probably not a real big deal except the itching can be a pain. avoid to long a hot shower and use as cool water for showers as you can tolerate. That is because if your skin gets dry it will itch more naturally especially in northern climes with dryer cold air in winter. it's unlikely much else. Occams razor. The simplest answer is probably. the most correct.I was thinking about the suppression of the hormones upstream from testosterone due to TRT. I noticed my body is a little achy on trt and have wondered if the suppression of pregnenolone and it's downstream hormones may be causing this. Anyone else experience these side effects? Delt with them in any way?