Gynecomastia and Estradiol levels

At what levels does high estradiol cause Gynecomastia?

Gyno is not common side effect on physiological trt doses unless one is genetically prone. There are also many who use/abuse testosterone/aas using supra-physiological doses and never experience gyno hence genetics will always have the final say.

Gynecomastia is not only related to excess estradiol but may also have something to do with the T:E ratio being unbalanced,
 
Being hypopituitary since I was 7 years old I suffered from Gynecomastia from an early age. I was put on TRT at age 50 and my pre TRT labs showed then my E2 (the womens test in Canada) was 225. I developed breasts by the time I was 10 years old. And my nipples always bothered me when young. Every shirt would irritate them, except very soft cotton t-shirts. But since starting TRT my breasts have reduced some... not a huge amount but enough that I don't feel overly nervous about it any longer. When I was young I obviously had low T and high E2.
 

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