GONADOERALIN VS HCG

BigVet73 · Oct 23, 2020

Anyone have some insight on Gonaderalin?

Cataceous · Oct 23, 2020

So far no evidence has been presented to show that gonadorelin can be used as a direct replacement for hCG. There are theoretical reasons to be skeptical, including the rapid and pulsatile nature of endogenous GnRH production, and the suppressive effects of TRT on the pituitary. I've shown that with a rigorous protocol gonadorelin can restore gonadotropins under TRT. But while these results are interesting and show some promise for improving TRT, the method is likely to be impractical for most.

BigVet73 · Oct 23, 2020

So why cant i get HCG anymore? Would it be better to not use gonadorelin while on TRT?

captain · Oct 23, 2020

You can get HCG. You may not be able to get compounded HCG.

Cataceous · Oct 23, 2020

BigVet73 said:
So why cant i get HCG anymore? ...

Some details here:

HCG being taken off of the FDA’s approved list? - Excel Male TRT Forum

Hey everyone. I’m trying to get the news and ideas about my clinic switching to gonadorelin because they say the FDA is no longer approving HCG for use anyone else know what to do?

www.excelmale.com

BigVet73 said:
... Would it be better to not use gonadorelin while on TRT?

This use should be considered experimental. My hunch is that at physiological doses there may be some benefits to it even if gonadotropins are not produced. But if you don't get gonadotropins then you don't have the benefits you'd get with hCG. Furthermore, the protocols being put forth by clinics offering gonadorelin are not remotely physiological.