estradiol

30 y/o male - good health/ diet/ sleep etc. New here and no former TRT/ AAS use. Key results from two different blood tests (5 weeks apart) are below. Today I went and saw a private hormone specialist (leger clinic - Dr Savage) who advised that I may benefit from TRT due to relatively low Free...

I have been reading this forum obsessively for the last few weeks. What an incredible group of guys you all are. I have only been on TRT for about 3 months so I am figuring things out. At 2 months my bloodwork looked good and I decided to add HCG because the doc recommended it. So I have...

I searched and I can't seem to get a answer. Question with LOW SEX HORMONE BINDING GLOBULIN = 8 Range: 10-50 Will Everyday or Every Other Day injections work to raise or lower E2 and bring SHBG up. I was under the impression that ED injections will actually cause E2 to be higher and bring up...

For those who don’t know my history, I have a consistent lowish estrogen problem because I can’t raise my testosterone dose high enough to aromatize enough e2, due to erythrocytosis. Using 60mg twice per week right now and that has my Hemoglobin at 17 and hematocrit at 50.9 so far. Going to...

Adding supplemental scrotal T cream seems to be the trend lately, and personally I've definitely seen some benefit. Based on information from some doctors and other board members it seems the DHT:E2 ratio is improved, which gives a better sense of well being and libido. However, couldn't the...

I've struggled with estrogen management since I began trt about a year ago. I've always injected Sub-Q and the research supports T levels through Sub-Q. However, at my Wit's end I decided to begin injecting in my deltoid about 2 weeks ago. It's really made a big difference in my estrogen side...

Hey guys, can high e2 cause anxiety? I know it can cause one to be more emotional which I have been and have been crying but my anxiety is through the roof!!! I am prone to anxiety and have been since I was little. There is alot of big changes going on in my life....bought a new house and...

GUYS. I need some advice HCG is all new to me... 1. Sorry this is so long , just trying to get all the info in here. so please glance at it 2. I have just Gotten a prescription for HCG (Pregnyl ) after almost 3 years on TRT ..50mg 2x a week I got the arimidex as well 3. I have not...

I was on TRT for about 18 months. Decided to stop and attempt a restart using toremifene. The restart was a success! I haven’t had any injection or any SERM since October 2018. My current labs are: Total T: 694 E2: 12.8 I’m concerned that my E2 is too low. Is it actually too low? Is this...

When I inject test cyp, I know levels rise then fall a bit several days later. What happens to E2? Say I inject twice a week and take .125 anastrozole each time. Does my E2 drop the first day or two due to the anastrozole then rise on day 3? I guess I am asking in this case if test and e2...

I was looking for something else, when I came across this study: Estradiol stimulates cortisol production by adrenal cells in estrogen-dependent primary adrenocortical nodular dysplasia. - PubMed - NCBI It's an old study and it has been performed on a single patient with ACTH-independent...

I am on the following: -40 mg test-c 2x weekly -500 iu HCG 2x weekly I recently discontinued my ai as it makes me feel very bad even at just .125 mg and brings my e2 to low 20s. I have a high SHBG, historically around 55-65 (15-55) and my Total T runs around 1100 with free T anywhere between...

I'm currently dealing with a few things that may or may not be TRT related. I scoured these forums to see if I could find help with no conclusive answers. Background: 38, 5'11", 205lbs TRT since Feb 2018, currently 138mg/week (3x) + 500IU HCG (2x) + .125mg Anastrozole 2-3x as needed DHEA 25mg...

I have been struggling with estrogen problems for over a year. I just can’t seem to get dialed in. I was at .1 anastrozole every 3 days, and after 19 days I went high, so I adjusted to .1 every other day. That brought me down to normal after a few days, then a little low, and now high after 15...

So as I posted in another thread, my E2 came back high (65) after my first 8 weeks at 160mg/week. Didn’t have much symptoms but defy and I agreed to lower me to 140mg/week and 0.1mg to 0.2mg Anastrozole weekly. I know it’ll take time for my dose change to reduce E2 symptoms but a few new things...

All of us are following our protocols quite blindly, trying to optimise but unsure what values to optimise to. The lab ranges vary between countries and labs. The NHS for example sets it upper T limit at 750 - whereas many people in the US naturally have higher levels than this and are perfectly...

If one was on a standard protocol of twice weekly injections, with a normal mid-range SHBG levels, how much could you expect Estradiol to vary between peak and trough levels? For example if someone had an E2 sensitive reading of something like 20 at their trough. Thanks.

Summary of my lab work: Okay total T Low Free T High SHBG Low LH Underperforming Thyroid Low E2 Estradiol senstive - 7.4 (normal = 8.0 - 35.0) Doctor has started me on 12.5 Clomid (EOD) and AI (Anastrozole) (3x per week) From what I gather, the treatment plan lis designed to elevate my free T...

Been a while since I was on this site, but I just discovered this dedicated Prolactin subforum, looks like theres loads of good stuff stickied, so have lots of reading to do! In the mean time I thought I'd post here. I started a thread in the TRT subforum a while back, and have since had a few...

I'm a long time lurker and haven't posted much (perhaps even never) but I felt I should contribute something in return: I have very mild gyno that I've had most of my life. As soon as my E2 goes up it starts getting sore. That's when I USED to take an arimidex and it would go away. This time...

39yrs old, 260lbs Iinitial labs had estradiol at 127.4 pg/ml) Began aromasin at 12.5mg 3x wk Two weeks later labs failed to detect estradiol (<2.5 pg/ml). In other words, crashed. Empirical symptoms consistent with low estrogen. This is not the first time I’ve crashed my estrogen to...

I have been on TRT for about 9 months now and have had very marginal results to date. The protocol (.32ml T-Cyp, .50ml HCG & .25mg Anastrozole - twice per week) has elevated my T levels but my Estradiol levels have tracked proportionally upward. To date I have had very minimal increases in...

A press release from the university that conducted the study was reported by Medical Xpress. Here's a short extract from the article: "A new study of older men carried out by The University of Western Australia has found there is a link between men who have higher levels of the sex hormone...

So not trying to start anymore drama with the round table or anything, but I just can’t stand to see these guys contradict themselves like this. They all say that water retention is not a side effect of high E2, and that it’s either in our heads, has more to do with our diet, or it’s from the...

I have been researching a lot of threads, not only on excelmale but many other boards as well. I noticed something interesting from the guys who pulled labs from both their peak and troughs. Men who were reading out between 20-30 on the sensitive E2 test were coming up as high as 60+ on their...

So after a long month of struggling with my erectile dysfunction I was able to be intimate with my wife for a whole session tonight )not saying that to boast there is a reason for me stating this) over the past month I have done tons of labs and research on here as well. People have been helpful...

50mg every 3.5 days of Test E 500iu every 3.5 days of HCG That protocol had my E2 @ 60pg/ml. and Test at 860 ng after 2 months it also put my Prolactin well over range. SHBG has been rock steady @ 35 nmol Changed to 100iu of HCG and in 6 weeks this brought my E2 down to 36 pg/ml. which I...

So after going over labs today with my doctor. (Not going to post them, just because essentially from all the research I have done on this forum and others things seemed pretty normal.) I will just post the basics real quick tbiugh TT-917 E2 (ultra sensitive)-17 SHGB- 26 Prolactin- I can’t...

So I am following up with my new doctor that I saw on Wednesday. It was 45 minute consult just to explain what was going on. Why I am seeing him, why I went on TRT. Basically I explained to him I am tired that of the ups and downs that I have been experiencing on TRT. These ups can be for a week...

So I got my lab results today Free T-17.7 TT-797 E2-35 (roche test) SHGB 36.1 PSA-.9 I have been having some libido issues along with a little bit of mood issues. 3 weeks ago I was great. Now, kind of in the middle. Having difficulty getting erections and maintaining. Sex drive is pretty low...

. History of estrogen: its purification, structure, synthesis, biologic actions and clinical implications. - PubMed - NCBI Clark Sawin Memorial lecture on History of Estrogen delivered at Endo 2018: Player: Clark T Sawin Memorial History of Endocrinology Lecture: Estrogens Over 90 Years...