Search results

I believe the widespread belief in the fitness community that saturated fat doesn't matter plus the fact that anabolic steroids worsen cholesterol ratios is responsible.

A study of steroid users at Danish fitness centers found increased use of hospital services as well as increased mortality over a seven year period. The abstract says: "In this retrospective matched cohort study, 545 male subjects tested positive for AAS in Danish fitness centres during the...

A meta-analysis of 27 placebo controlled trials found testosterone therapy is effective in treating depression in men. The abstract says: "Random-effects meta-analysis of 27 RCTs including 1890 men suggested that testosterone treatment is associated with a significant reduction in depressive...

The Cooper Center measured testosterone levels of men during patient asessment and did a multiple regression to see what factors testosterone levels were associated with they found that testosterone levels were inversely correlated with BMI and correlated with aerobic fitness, but not correlated...

"Men subsequently started injectable ND at half the dosage of their current testosterone regimen with all other medications kept constant." So presumably the dose was between 50-100 mg per week.

A retrospective observational study of 411 obese hypogonadal men found that testosterone undecanoate injections significantly decreased weight and waist circumference. The conclusion of the study says: "Testosterone therapy appears to be an effective approach to achieve sustained WL [weight...

"Under its new plan, the FDA is seeking to more closely define the necessity of compounded medication, stressing that they 'should only be distributed to meet the needs of patients whose medical needs cannot be met by an FDA-approved drug.'” I thought competition was supposed to be a good...

Testosterone pellets have been placed on the "difficult to compound" list, preventing compounding pharmacies from manufacturing them. A petition to reconsider this decision was denied. If I read the decision correctly, it was because proper procedure for contesting the decision was not followed...

Another meta-analysis looks at the existing studies and finds no evidence testosterone therapy increases thromboembolism. The abstract says: "While regulatory bodies have warned about increased risk of venous thromboembolism (VTE), published clinical data supporting an increased risk for VTE...

The title says it all. The abstract says: "This was a preliminary cross-sectional analysis of the baseline data from 92 healthy men (mean ± standard deviation, age 33 ± 6 years, body mass index [BMI] 24.7 ± 6.1 kg/m2). Sleep duration was correlated with testicular volume. The significance of...

The experiment induced micropenis in rats and then treated the rats with a combination of growth hormone (GH) and testosterone. The researchers noted that treatment of micropenis with testosterone alone leaves the penis at less than normal size, but combining treatment with GH more successful...

The abstract says: Erectile dysfunction (ED) due to androgen deficiency is rare in the young population. We retrospectively evaluated in this study men aged 18–40 years presenting with ED from 2015 to 2017. The International Index of Erectile Function-5 (IIEF-5) and Erection Hardness Grade...

A mouse study demonstrates that inguinal hernias are cuased by the conversion of testosterone to estrogen in the abdomen. The abstract says: "Inguinal hernia develops primarily in elderly men, and more than one in four men will undergo inguinal hernia repair during their lifetime. However, the...

There's good evidence that Vitamin D supplementation protects against respiratory illnesses, including influenza. The protection is greatest in those with the lowest Vitamin D levels, es you would expect. I don't have a strong opinion on the flu vaccine, except that if you get it, make sure it...

Analysis of hormone levels in older men in Sigapore suffering from sarcopenia showed that both dysregulated insulin/ghrelin and testosterone are responsible for muscle wasting. The full text of the article is online. "Insulin signaling and energy metabolism (ISEM: denoted by insulin, C‐peptide...

Blood levels of 25 Japanese men who were HIV positive were measured. 13 of the men also had low free testosterone levels. Levels improved after one year of anti-retroviral therapy. Here is the abstract.

Google has produced a map of the most searched for health symptom by state. If you're looking for a business opportunity, open a testosterone clinic in Nebraska, because the most searched for symptom in Nebraska is "signs of low testosterone." Indiana gets an honorable mention for "uncircumcized...

A report on adverse effects of testosterone supplementation in a rat model. There;s no mention of the dose given to the rats. I've heard that in anabolic doses, steroids can increase blood pressure. No journal article to link to, just this news report: "Recent findings will be presented today...

A study of patients found that men with a high triglyceride to HDL cholesterol ratio were likely to have low testosterone and SHBG levels. More evidence that testosterone levels should be part of routine screening for older men. The abstract says: "This cross-sectional study included 1055 men...

While doing my usual search for articles on testosterone, I stumbled across a blatant example of SEO optimization. A bunch of tweets all linking to the same article on "The Hidden Dangers of Testosterone Replacement Therapy." The tell tale sign is that all the tweets had the same wording, they...

Antares plans to sell Xyosted for between $450 and $500 for a month's supply. For the difference in price between that and a 5 ml vial of testosterone enanthate I think you could hire a nurse to come to your home and do the injection for you. Totally off the subject, but Antares is the...

I run across some pretty stringe stuff on the Internet while hunting for studies. This is one of the stranger ones: a website for a startup called TestiStim hat wants to sell electrical underwear that will boost low testosterone levels. From their front page: "TestiStim is an early stage...

Men with lver cirrhosis were given blood tests for hormone levels. Men with the most severe cirrhosis had lower testosterone and elevated prolactin. The men were followed for an average of 13 months and liver events and death were correlated with low testosterone levels. The abstract...

The press release says: Macquarie University Hospital is participating in what will be the largest clinical trial to date assessing the effect of testosterone supplementation on reducing amyloid – a protein that develops in the part of the brain that affects memory and learning. Beta amyloid...

98 men with type 2 diabetes (T2D) we given a standard questionaire on erectile dysfunction (ED). Results were compared to blood levels of vitamin D (25(OH)D) and the men with the more severe ED had lower Vitamin D levels. The abstract says: "The present study evaluated the relationship between...

Actor and congressional candidate Antonio Sabato Jr. is in the news after receiving testosterone replacement therapy. Fox News reports: Former model and soap star-turned aspiring politician Antonio Sabato Jr., said he “could have sex all day” after having testosterone pellets injected into his...

An observational study of men on testosterone replacement therapy shows positive results. The abstract says: "In a single center study, the authors treated 69 men with testosterone deficiency syndrome (TDS). The average age was 57.84 years and the follow-up period was 94.62 months. All the men...

A randomized clinical trial followed men for 3.8 years to see if testosterone replacement therapy (TRT) reduced mortality in men with type 2 diabetes mellitus (T2DM). It did, even though it had no effect on cardiovascular disease (CVD). rates. The abstract says: "We studied 857 men with T2DM...

Some measures of success continued to improve in men with type 2 diabetes on testosterone replacement therapy. Others reverted to the norm of the placebo group. The abstract says: "Improvement in HbA1c and weight at the end of the RCT [randomized clinical trial] and open-label phase in men on...

Although the study was on rats, the same probably applies to men. The dose was large 2 mg/kg/d of testosterone propionate, which translates to 160 mg/d for an average sized man, a large dose even for a bodybuilder. The article concludes: "In conclusion, we have provided evidence supporting...

A study found that blood levels of testosterone drop after a glucose challenge or eating a meal. This result suggests blood levels of testosterone should be measured in a fasted state. The news report says: "Sixty men (23-97 years) without pre-diabetes or diabetes who had normal total...