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Another study presented at the recent American Urological Association Conference found that over the time period studied mean testosterone levels fell by 25%. A news article explains: "From 1999 to 2016, testosterone levels have declined in adolescent and young adult men (AYA), according to...

When Covid-19 came along, most countries and states within the US responded by locking down everything as tightly as possible. It seems with the benefit of hindisght some of these measures were counterproductive. Among these I think are banning elective medical procedures and closing grade...

This study finds little correlation between the two: "We evaluated the association of circulating levels of total and free testosterone, and of sex hormone binding globulin (SHBG), with the risk of cancers of the pancreas, kidney, and brain, and of total and free estradiol with the risk of...

A new placebo controlled study of the use of testosterone undecanoate to prevent type 2 diabetes in older obese men found it reduced the risk by 40%. The study was presented at the recent meeting of the American Diabetes Association, the abstract is online. There is also an article about the...

I'm seeing a lot of carbophobia in these comments. There are healthy carbs and unhealthy carbs. Healthy carbs are fruits and unrefined plants. Unhealthy carbs are added sugars and refined flours. If you believe otherwise, please post a link to a journal study (not some doctor's opinion) showing...

I assume youŕe talking about this study when referring to MRFIT. The usual problem with dietary advice is adherence. Anecdotally at least, the keto diet is a difficult diet to adhere to, with the "keto flu" and other unpleasant symptoms. You may do well on it and judge it from your experience...

What the meta-analysis shows is that people who reduced the amount of saturated fat in their diet also reduced the number of cardiovascular events. It didn't seem to matter whether they replace the saturated fats with polyunsaturated fats or carbohydrates. The latter is the only surprising part...

Cochrane Review has published a new meta-analysis on the relation between saturated fat in the diet and cardiovascular disease. Their results showed that reducing saturated fat reduced cardiovascular disease (CVD) events, but not morality. The abstract said: "We included 15 randomised...

I don't know Mike Mahler, but fitness coaches sometimes have exaggerated ideas of how much protein one needs. When I started TRT I hired a personal trainer and I asked him how much protein I should eat. He said 1.3 to 1.5 grams / kg of body weight, which for me works out to be 120 grams. He had...

No, I'm not a vegan. The point is, though, that both a vegan diet and a diet with meat can be healthy if they follow the general rules of a healthy diet and unhealthy if they do not. These rules are: Eat unprocessed instead of processed foods Eat whole instead of refined foods Avoid fried foods...

Hereś an interesting study of how plant based diets affect testosterone levels. The epithet "soy boy" is used not just to describe men who consume soybean products, but also men who avoid meat. So how does a vegetarian or semi-vegetarian ("plant based") diet affect testosterone levels? Not at...

From Yahoo News: The U.S Food and Drug Administration said on Wednesday it had found high levels of a possible cancer-causing impurity in some versions of the popular diabetes drug metformin. The agency is reaching out to companies whose drugs had N-nitrosodimethylamine (NDMA) over accepted...

The Guardian is reporting a global shortage of estradiol. This affects both HRT and contraception. The focus of the article is on a current shortage in Australia and New Zealand. Perhaps disruption of the supply chain by covid-19, perhaps something else. "The affected products are distributed...

An asessment of the issue of hematocrit increase after testosterone therapy and whether current guidelines are justified. The abstract is online and the full paper can be downloaded from the link. The conclusion is: "Testosterone therapy (TTh) can effect an increased hematocrit via poorly...

Testosterone levels are still falling in young men, quite significantly. It's a good time to be in the testosterone replacement business. From the article: In an analysis of data from 4045 adolescent and young men aged 15 to 39 years who participated in the National Health and Nutrition...

Only a mouse study, but suggests that healthy testosterone levels play an important role in helping the immune system fight off cancer. Here is the abstract and the full article can be downloaded. ¨In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma...

There's an initial rapid weight loss on the ketogenic diet because glycogen stores are depleted and glycogen holds water in the muscles. The initial weight loss is mostly water. Over the longer term ketogenic diets do well for weight loss, but it's thought mostly because of the sameness of the...

A video has been viewed more than 100,000 times in multiple posts on YouTube, ******** and Twitter in which a purported Philippine doctor claims ingesting semen could cure a patient infected with the novel coronavirus, citing a 2016 scientific study. The claim is false; the authors of the 2016...

A study evaluated the risk factors of men admitted to a hospital in Germany for Covid-19 and found that one factor is low testosterone levels. This run contrary to recent discussion in the media where it has been argued that testosterone raises the risk for Covid-19. The preprint is on MedRxiv...

I believe that most of the time required to develop a vaccine or any other drug is the time needed for safety and efficacy testing. I hope they don't shortcut this process for the new vaccine, but already it looks like they're skipping the animal testing.

I believe the bodybuilder Ryan Humiston follows a plant based keto diet. Plant based is hard and keto is hard. I would think doing both is doubly hard.

Everyone is hoping a vaccine will soon be available to prevent Covid-19. But one unexpected result that may lead to problems for men on this forum is that the vaccine will require a great number of stoppered vials to hold it and this may lead to a shortage of vials for testosterone. The article...

This is a review article discussing the treatment of hypogonadism in HIV positive men, with a discussion of several cases. The full text of the article is available online. The introduction says: "Hypogonadism commonly affects HIV-positive men and is associated with a variety of clinical...

The diets which have recently gotten the most attention in the media are the ketogenic and low fat plant based diets. Up until now there have been no studies comparing the two diets head to head in a controlled clinical setting. But now there is, a crossover study where the participants ate each...

Dr. Michael Greger says there's good evidence Vitamin D decreases all cause mortality, which was my original reason for taking it. Any benefit in preventing covid-19 is a bonus: "While the majority of observational studies may show a link, where you simply measure vitamin D levels and disease...

The paper says it is the first study to show that Vitamin D levels are associated with Covid-19 mortality. Currently I take 5000 IU of Vitamin D EOD and after reading this paper will step it up to every day. The abstract is at the link and the full paper can be downloaded as a pdf there. This...

Computer simulations looked for natural compounds that bind to the coronavirus spike to prevent it from docking to cells. Estrogens and the phytoestrogens in soy were the best candidates. And no, soy phytoestrogens won't feminize you, their estrogenic activity is much weaker than estrogen. The...

From the abstract: Whether androgen deficiency among men increases the risk of cardiovascular (CV) events or is merely a disease marker remains a subject of intense scientific interest. In this post hoc analysis of men with available baseline plasma T concentrations, we examined the...

According to a thread on Twitter, which is from a local news reporter, the Colorado Attorney General has shut down three Low T Center locations, because they do not provide "emergency or life-saving procedures.": Colorado's Attorney General directs Low T Centers to stop claiming its procedures...

The standard advice is, to invest for the long term, buy Vanguard Index Funds. Invest 60% in stocks and 40% in bonds. More info here.

Want to Live Longer? Ear More Fruits and Vegetables Fruits and vegetables emerged as the healthiest foods to eat in a massive research study. The study found a reduced risk of heart disease, cancer, and stroke and premature death in people who consume 10 daily servings of these plant foods as...