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  1. G

    Can Enclomiphene replace HCG in PCT?

    I don't know what the best would be. You might look into including Kisspeptin however I don't know whether that would over-ride the suppression to produce LH. You may just have to go with clomid and/or enclomiphene alone. You didn't say which ester of Test you were going to use but a shorter...
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    Can Enclomiphene replace HCG in PCT?

    Here's my take. Question 1) Almost certainly not. The enclomiphene would be to stimulate LH, however the combination of Test (Highly suppressive) and NPP (Almost as suppressive) would almost certainly out-weigh the enclomiphene. HCG is used because it is similar to LH so your body does not have...
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    Need help to get shredded and improve protocol

    Several things: - As Dr. Fung says, the Holy Grail of long-term sustainable fat loss is maintaining metabolic rate. Many of the people I know who've had long-term fat loss success use an undulating diet approach of underfeeding or total fasting two days per week, with higher calories the other...
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    Testosterone Levels Too High?

    Ok, I agree with madman that unfortunately it takes longer than most people are willing to wait to give a dosage a fair shot. There was a good swirl-o-gram from 5 years or so ago that captured the general timeframes for TRT symptoms to improve but unfortunately I don't have it. Perhaps it is...
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    Testosterone Levels Too High?

    What was the reason for the increase? How did you feel/perform at lower doses? "Safety" has a lot of nuance, but generally going with a dose at which higher doses offer no benefits will be a safer approach than higher doses.
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    Patients taking hormones seem to be at a higher risk of tendon injury

    The basic premise of this thread would seem to be disproven by the use of "hormones" in strongman and powerlifting. There may be risks due to faster growth of muscles vs. tendons, but tendons have to increase in strength to accommodate the additional strength while someone is using hormones, so...
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    Who does not need to use an ED med?

    Note that Primo reduces libido in some people. This may be due to the anti-estrogen affects, so hopefully it will still leave you in a good spot.
  8. G

    Hi all, a brief introduction, curious opinions please

    Another caution about TRT that I forgot in my initial response is that for some people it can cause Resting Heart Rate to rise significantly for no apparent reason and without a root-cause way to resolve. That happened to me and I've seen it reported by numerous others. That is probably not a...
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    TRT related to Osteoarthritis? Is there life after a Osteoarthritis diagnosis?

    My understanding regarding what plants "want" is that they want their seeds to be spread around with a helping of fertilizer added, but what they don't want is for their seeds to be digested and hence destroyed. Eating grains therefore should be viewed with suspicion, but eating the fruits or...
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    TRT related to Osteoarthritis? Is there life after a Osteoarthritis diagnosis?

    You might try using glycine as a sweetener. Besides being an essential supplement, it is very sweet-tasting. I use it as a sweetener on cranberries and it works fantastically well although I don't know how it would hold up if heated.
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    TRT related to Osteoarthritis? Is there life after a Osteoarthritis diagnosis?

    If you're noticing digestive issues they are probably something that you need to address, possibly via digestive enzymes, something that promotes the creation of stomach acid, or some sort of microbiome improvement. I think Paul Chek may be a good source of information on this. This could happen...
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    Hi all, a brief introduction, curious opinions please

    The thing that jumps out to me is "permacutting". This could explain every single one of your symptoms including low T, and it has likely slowed your metabolism down. Until you get your body into a state of abundance you won't know what (if anything) else needs to be addressed or how to do it. I...
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    Hi all, a brief introduction, curious opinions please

    Welcome to the forum. A lot to unpack here but here are some thoughts. - I agree with Vince that going with a clinic like Defy that specializes in hormones is the way to go as far as clinicians are concerned - If I had it to do over again I would certainly start with something like clomid or...
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    Detection of microplastics in the human penis

    It's fairly simple and cheap to get a counter-top water filtration pitcher and then pour the water into a glass container. I use the one from Clearly Filtered (no affiliation) which claims to remove bad stuff like flouride and microplastics but leave minerals in the water. Detoxing microplastics...
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    Did SSRI's cause problems for your TRT protocol?

    Please stop making definitive statements. It's fine to say that there isn't a known mechanism that you're aware of, however the body is a complex web of feedback loops, regulatory mechanisms, and metabolic cascades which we are far from understanding with great precision, so to the OPs question...
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    Testosterone propionate supposedly the best ester?

    I tried prop numerous times and never had any issue with pain of any kind. I think the people having issues are using much higher doses than most of us would use. My TRT weekly total is about 80-90mg.
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    Fat loss diet optimization ++

    TMG/Betaine has fat loss properties. Choline/Inositol may help with visceral fat. A low dose of metformin may help. Anything which is a mitochondrial "uncoupler" may help (that's how DNP works) but can come with other issues, nicotine being a good example.
  18. G

    Testosterone propionate supposedly the best ester?

    The best ester is the one that you do best with. I've tried prop many times (no PIP) and I just seem to do a bit better with Cypionate. Theories are fine as a way to develop hypotheses about what might work, but only experimentation and refinement will tell you what works for you. I do think...
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    TRT related to Osteoarthritis? Is there life after a Osteoarthritis diagnosis?

    What you were taking sounds reasonable to continue, but I would have expected some improvement by now. DMSO is another must-do, but IMO the most important think is light activity in the problem areas and maintaining a strength routine everywhere else. This does a lot of things like getting blood...
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    TRT related to Osteoarthritis? Is there life after a Osteoarthritis diagnosis?

    I'm a strong believer that TRT is a net benefit to tendons, however tendons do not grow as fast as muscles so it is important to progress at a moderate pace. I think you are likely dealing with two issues; 1) Older people have to deal with random things in the body causing trouble. That is just...
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    TRT related to Osteoarthritis? Is there life after a Osteoarthritis diagnosis?

    A few ideas... - I doubt if TRT is a big factor, although if your estrogen is low, then that could cause joint pain - See the "fixes for joint issues" thread. A lot of Osteoarthritis is due to an immune response, basically a food sensitivity. In my case eliminating whey protein was a big...
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    My Experience On Jatenzo (Oral TRT) Log

    Cravings may be due to a microbiome issue. The bad gut bacteria may have been awakened by the carbs. So, the carbs may not be the problem. Ben Greenfield recently did a podcast where he covered a lot of the tests which can be used to check gut health and a good holistic doc, if you can find one...
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    Nandrolone (Deca) Base TRT Trial

    Here is an excerpt from an article in Life Extension Magazine: A little known side benefit to the class of antihypertensive drugs known as angiotensin II receptor blockers is that they enhance insulin sensitivity, increase utilization of fat as energy, and improve mitochondrial...
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    My Experience On Jatenzo (Oral TRT) Log

    You should check out Paul Saladino's animal based diet. I have long advocated the Perfect Health Diet by Paul Jaminet which is what many people (e.g. Saladino, Mercola and others) seem to finally be coming around to. Some people can do fairly well for a while on close to zero carbs but most...
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    Current Defy Medical Restart Protocol

    My two cents...I wouldn't even think about another "cycle" until you've gotten back to steady state for at least 6 months. Deca is long-acting and you should have stopped it already. NPP would have been a better choice. You should have been using HCG throughout. Use clomid or nolva at moderate...
  26. G

    Enclomiphene dose

    You logic sounds reasonable, however there may be other variables involved. For example, if Zuclomiphene and Encomiphen compete for the same receptors, then removing Zuclomiphene could make the same dose of Enclomiphene effectively a higher dose. Hence, starting at a lower dose and working up if...
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    Where to get Enclomiphene?

    I believe that's a corticosteriod
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    Nandrolone (Deca) Base TRT Trial

    A quick search suggests that Testosterone in general pushes the renin–angiotensin–aldosterone system (RAAS) in the direction of higher blood pressure, however this is likely highly variable between people and some people may be hyper-responders. I don't seem to have this issue but something...
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    Restoring Nitric Oxide to the Body

    There is another thread on long-term cialis, but note that this class of drugs blocks the enzyme that breaks down nitric oxide, but they don't directly produce it, so if someone is not making enough in the first place, these drugs won't work well.
  30. G

    Patients taking hormones seem to be at a higher risk of tendon injury

    You might want to review the "fixes for joint issues" thread and see if that gives you any ideas. I know of people who have had complete healing with DMSO, and for me the combination of DMSO, BPC-157 and something from the growth hormone family has worked well. Obviously I don't know how much of...
  31. G

    Where to get Enclomiphene?

    Since enclomiphene is a subset of clomid, technically you would be getting a lightly higher dose of enclomiphene than is in the same dose of clomid, but it seems reasonable to start there.
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