Context is crucial. I'm natural at 104 ng/dL, Free T in the 2.89 ng/dL, both well below range in the late afternoon and I feel amazing and look and feel better than when I was at 592 ng/dL when on TRT/Jatenzo.I've been on TRT for close to four months and am on 200mg/ wk of test cyp. I am doing ED injections. I am thinking of dropping my dosage by 20%. Any feedback would be greatly appreciated!! Thank you!
Your labs look good. How are you feeling? Having any issues? If not, I see no reason to change anything.I've been on TRT for close to four months and am on 200mg/ wk of test cyp. I am doing ED injections. I am thinking of dropping my dosage by 20%. Any feedback would be greatly appreciated!! Thank you!
I've been on TRT for close to four months and am on 200mg/ wk of test cyp. I am doing ED injections. I am thinking of dropping my dosage by 20%. Any feedback would be greatly appreciated!! Thank you!
Context is crucial. I'm natural at 104 ng/dL, Free T in the 2.89 ng/dL, both well below range in the late afternoon and I feel amazing and look and feel better than when I was at 592 ng/dL when on TRT/Jatenzo.
Imagine I came here as a new member and posted my results without mentioning how I feel. Everyone would be giving me the wrong advice.
Not a complete set of lab work to be able to advise, CBC would be nice as well as knowing how well you're responding to treatment.
Fasting glucose 85, budging veins, ever increasing energy and erections improving every day. Even my sleep quality and duration has never been better.You have absurdly low FT plain and simple!
Nothing healthy about this here!
Fasting glucose 85, budging veins, ever increasing energy and erections improving every day. Even my sleep quality and duration has never been better.
How’s that for healthy?
I had a higher fasting glucose on TRT because I pushed beyond what my genetics can handle.
You of all people should know that it’s more than just about the absolute hormonal value that matters, the type of androgen receptor, androgen receptor sensitivity, receptor density, as well as the abilities for tissues to respond is a bigger factor than any hormonal lab value.
There’s only one possible explanation, I have very short gene CAG repeat numbers. A little testosterone goes a looong way for someone like me.
Also men with shorter gene CAG repeat numbers tend to have higher rates of prostate cancer. None so far in my family.
Why did you come off your oral T, that you have said on the forum you were so happy with?Fasting glucose 85, budging veins, ever increasing energy and erections improving every day. Even my sleep quality and duration has never been better.
How’s that for healthy?
I had a higher fasting glucose on TRT because I pushed beyond what my genetics can handle.
You of all people should know that it’s more than just about the absolute hormonal value that matters, the type of androgen receptor, androgen receptor sensitivity, receptor density, as well as the abilities for tissues to respond is a bigger factor than any hormonal lab value.
There’s only one possible explanation, I have very short gene CAG repeat numbers. A little testosterone goes a looong way for someone like me.
Also men with shorter gene CAG repeat numbers tend to have higher rates of prostate cancer. None so far in my family.
How you are feeling is the crucial context we are missing here, without which your lab numbers are meaningless.I've been on TRT for close to four months and am on 200mg/ wk of test cyp. I am doing ED injections. I am thinking of dropping my dosage by 20%. Any feedback would be greatly appreciated!! Thank you!
After coming off the beta-blocker, which was causing hypotension, things changes and I could no longer tolerate sunlight, foods with vitamin D or vitamin D supplements even though I was deficient.Why did you come off your oral T, that you have said on the forum you were so happy with?
It's well known that beta-blockers allow vampires walk in the daylight by reducing the oxidative stress associated with UV light exposure. Dropping the beta-blocker then would have unmasked your underlying vampirism. Additionally, iron is toxic to vampires unless consumed as fresh blood. We finally have a diagnosis that explains everything you've observed.After coming off the beta-blocker, which was causing hypotension, things changes and I could no longer tolerate sunlight, foods with vitamin D or vitamin D supplements even though I was deficient.
Feel better on trt or not on trt?? Kind of confused because above you said you feel better now than you did on trt.After coming off the beta-blocker, which was causing hypotension, things changes and I could no longer tolerate sunlight, foods with vitamin D or vitamin D supplements even though I was deficient.
TRT changes my iron status too much by suppressing hepcidin and this causes problems. Vitamin D makes more iron bioavailable as does TRT by suppressing hepcidin.
I feel better on TRT.
I meant feel better off TRT.Feel better on trt or not on trt??
Feel better on trt or not on trt?? Kind of confused because above you said you feel better now than you did on trt.
Either way, it’s your life and hope you find something that works and makes you feel good enough to enjoy your time on this planet. I do agree with madman though, that free t level seems chronically low and not what most would consider even close to a healthy level. If you feel better there then hopefully you’re an exception.
Also, if you are such an outlier that makes me reconsider your constant praise of oral testosterone. Not saying it didn’t work for you, but you seem to be a rare specimen so it’s quite possible(likely) that your success with it is not the norm for most subjects. And that’s backed up by lots of other anecdotal stories from people who failed to find success with it.
Maybe there is also a cost/insurance problem or unwillingness of some urologist to prescribe the 600-800mg dose. I experienced that with the androgel, 2-3 pumps was the limit I could get prescribed.Would not go that far here!
Much more to the story.
The downfall here is many men jumping on oral TU start on the lower end dose let alone do not always put in the time to truly gauge the effectiveness of the protocol and even then many bailout before even titrating up in dose which may be needed in many cases in order to achieve a high enough TT/FT.
Even when using oral TU (Jatenzo or Kyzatrex) steady-state is achieved fairly quick but one still needs to put in the time let alone titrate up in dose if need be before jumping to any conclusions.
Another critical point that needs to be made here is there are a fair amount of men already on injectable T running high let alone absurdly high FT levels trough/steady-state that decide to give oral TU a go.
This is going to make a huge difference here as to how one feels when first starting oral TU as it will take time for the body to adapt to the 2 daily peaks/troughs vs coming down from the high/absurdly high trough/steady-state FT levels achieved on injectables.
These guys are already amped up on T 24/7!
As you should very well know from hanging out on this forum let alone those other so called men's health/HRT forums loaded with all those blast n cruizerrzzz pushing that more T is better mentality bullshit that unfortunately most men are overmedicated on T from the get-go!
You have guys running around with high/absurdly high trough/steady-state FT levels well beyond their genetic set-point.
Blown the suicide doors of the LAMBO here!
FT levels through the roof 24/7!
No way most of these men could truly give an oral TU protocol a fair shake!
You would need to bite the bullet and expect to feel shitty from the get-go as again it will take time for the body to adapt.
Put money on it if the individual started TTh using oral TU and put in the time let alone was titrated properly so he achieved a high enough TT/FT level many would fair well overall on such protocol!
Even much better when it comes to the sides (cosmetic/blood markers) than most using injectable T!
I could name off quite a few of the top uros treating men with oral TU that have many satisfied patients and it was mentioned in a recent interview Nelson posted with Marius Pharmaceuticals CEO Shalin Shah that common dosing regimens for Kyzatrex are 300-400 mg BID (2X/day) /600-800 mg daily!
The starting dose is 200 mg BID/400 mg daily.
KYZATREX (oral testosterone undecanoate) now available in all states across the US
Did you get any nasty side effects by the way? None. I am looking at all the warnings and one of them says increase risk of death. That's a load of sh**! There's an increase risk of death living life, like crossing the street. There's increase risk of death with any other medicines.www.excelmale.com
Oral TRT Products: Jatenzo, Tlando, Kyzatrex, & DiTest
I have tried Jatenzo on a few occasions, but never got to seven days. Have you tried Jatenzo after no injections for a couple of weeks? Stacking both may be causing your problems. I felt bad on Jatenzo 2, 3 and 4th week and I’ll bet it has to do with the cypionate leaving my system and my T...www.excelmale.com
Would not go that far here!
Much more to the story.
The downfall here is many men jumping on oral TU start on the lower end dose let alone do not always put in the time to truly gauge the effectiveness of the protocol and even then many bailout before even titrating up in dose which may be needed in many cases in order to achieve a high enough TT/FT.
Even when using oral TU (Jatenzo or Kyzatrex) steady-state is achieved fairly quick but one still needs to put in the time let alone titrate up in dose if need be before jumping to any conclusions.
Another critical point that needs to be made here is there are a fair amount of men already on injectable T running high let alone absurdly high FT levels trough/steady-state that decide to give oral TU a go.
This is going to make a huge difference here as to how one feels when first starting oral TU as it will take time for the body to adapt to the 2 daily peaks/troughs vs coming down from the high/absurdly high trough/steady-state FT levels achieved on injectables.
These guys are already amped up on T 24/7!
As you should very well know from hanging out on this forum let alone those other so called men's health/HRT forums loaded with all those blast n cruizerrzzz pushing that more T is better mentality bullshit that unfortunately most men are overmedicated on T from the get-go!
You have guys running around with high/absurdly high trough/steady-state FT levels well beyond their genetic set-point.
Blown the suicide doors of the LAMBO here!
FT levels through the roof 24/7!
No way most of these men could truly give an oral TU protocol a fair shake!
You would need to bite the bullet and expect to feel shitty from the get-go as again it will take time for the body to adapt.
Put money on it if the individual started TTh using oral TU and put in the time let alone was titrated properly so he achieved a high enough TT/FT level many would fair well overall on such protocol!
Even much better when it comes to the sides (cosmetic/blood markers) than most using injectable T!
I could name off quite a few of the top uros treating men with oral TU that have many satisfied patients and it was mentioned in a recent interview Nelson posted with Marius Pharmaceuticals CEO Shalin Shah that common dosing regimens for Kyzatrex are 300-400 mg BID (2X/day) /600-800 mg daily!
The starting dose is 200 mg BID/400 mg daily.
KYZATREX (oral testosterone undecanoate) now available in all states across the US
Did you get any nasty side effects by the way? None. I am looking at all the warnings and one of them says increase risk of death. That's a load of sh**! There's an increase risk of death living life, like crossing the street. There's increase risk of death with any other medicines.www.excelmale.com
Oral TRT Products: Jatenzo, Tlando, Kyzatrex, & DiTest
I have tried Jatenzo on a few occasions, but never got to seven days. Have you tried Jatenzo after no injections for a couple of weeks? Stacking both may be causing your problems. I felt bad on Jatenzo 2, 3 and 4th week and I’ll bet it has to do with the cypionate leaving my system and my T...www.excelmale.com
I think that’s a good point about people going from injections to oral, and it would take some time to adjust to daily rollercoasters while also not being elevated more throughout the week. However, I also think that the term “absurdly high” is pretty subjective, and sitting at or slightly above the top of the reference range isn’t necessarily a bad thing. If a person takes care of themselves with diet, exercise, and sleep.. then I’d say being on the higher end is probably a better thing. It’s definitely preferential for building muscle and bone density, which is very important for longterm health. You are correct though, that being too amped up constantly is not good…but I’d say that is easy to identify by sleep issues, not necessarily just based on what the levels are. In other words, if you’re sitting above the top of the range 24/7 but sleeping well then your body is adapted to the environment and won’t suffer from the negative of poor sleep. That’s just one example, but applies to lots of other areas like anxiety or hematocrit. If hematocrit is slightly elevated but all other markers look good then the body is well-adjusted to the levels and the hematocrit would not be a concern. But yes, obviously there are things to watch out for when it comes to injections. At the same time though, there are unique concerns that are introduced by oral administration of testosterone that wouldn’t apply as much when it comes to injections.
But again, I’d say you are correct that it’s quite possible many people could benefit from oral test. And it’s probable some people would even prefer that route. The main thing would be to know the pros and cons of whichever path you take, and monitoring/adjusting accordingly. Either way, I say the more options the better. And I’m sure we can all agree that it’s a good thing research is focusing on this front so that we can continue to improve understanding and options going forward.
Age category (years) | Median mFT (ng/dl) | 95% mFT reference range (ng/dl) |
18-29 (n=140) | 12.0 | 6.7-25.3 |
40-49 (n=207) | 8.1 | 4.3.14.2 |
50-59 (n=146) | 7.1 | 3.8-12.8 |
60-69 (n=126) | 6.4 | 3.4-11.7 |
70-79 (n=125) | 5.6 | 2.7-8.7 |