Realistic expectations are most important! I started at age 50 after things just caught up to me from high stress 24-7-365 business life. It really made a big impact on body composition, Ha1C and others....It was not the magic bullet however. You cannot fix 35 years of high stress burnout with an injection. I will say it has made my life better and my wife at age 59 looks like she could be 50. Be realistic and okay with smaller gains.....