TRT Journey, Next stop Kyzatrex

[funghi2]

We’re talking about anything in large quantities being somewhere in the body where you wouldn’t typically see large quantities of said substance: hundreds of milligrams of T or TU 2x/day in the lymphatics. It’s just a personal concern of mine. I have no evidence to support T or TU in the lymphatics being an issue.

I stand by my previous general statements regarding the relationships between SHBG/metabolic health and SHBG and large doses of T. That said, lots of factors can influence SHBG in addition to TRT: diet/fasting, better thyroid health or thyroid supplementation, etc.

dont hormones eventually travel thru the lymphatic system anyway? its the quantity you are worried about?

 

[jnde207]

Hello all, been lurking around this treasure chest of a site. so much excellent info here, thanks to all that post. im 48 year old male, in decent shape. Have played around w bio hacking for 15 years or so. I prob have Familial hypercholesterolemia, my cholesterol is usually in the 380 - 425 range total. Im also slightly hypothyroid. so i take 1.5gr armour ED. My docs have pushed to put me on statins for many many years but i just dont see the point as all my inflammation markers are normal to low. I even got a calcium score done recently bc that was supposed to be the dr's smoking gun to show the damage high LDL was doing to me, my score was zero. anyway, i used to weigh 232 (height 5 10), but went on IF protocol 2 years ago and now fluctuate between 180 and 190. i started mounjaro as well last year.

Anyway, Ive been on and off test for many years as my blood tests are usually between 180 and 250 unmedicated. my most recent trial was natesto. great peaks at 1100 but in between doses crash to 190. and man o man was that annoying putting that oil up your nose 3 times per day. miserable. just started Kyzatrex 2 weeks ago, have to say i feel amazing. im going to schedule labs shortly to see where im at. my main question is this, i try to stay away from Prop bc i want a more natural pulsing of testosterone. but i also dont like the idea of the troughs getting down below 200! is this belief of mine unfounded? does anyone have a graph that shows normal pulsing levels? i saw one online that showed a base of around 500 that rose to 800 and went back down to 500, but im not sure if thats typical. I dont love the idea of sticking myself w pins EOD either. Would it be helpful to do a small dose of ENT or PROP, lets say 50 -100mg per week just to raise my floor level of test while staying on the TU to keep the daily pulse going? As far as testing, is there any need to test for the trough level as well as peak? I was thinking of buying a few salivary testosterone kits and doing one every 3 hours from waking pre TU dose to 2nd dose. So 8am (then take TU right after), 11am, 2pm, 5pm, 8pm. would you change timing on that? is salivary testing for this a valid approach?

Also considering adding a few peptides like cjc/ipa, are you guys fans?

Lastly, im sure its buried in the pinned posts somewhere but is there a guide to where you want your labs to be as far as E2, SHBG, FH, LH etc.?

I take 200mg of test E every 5 days to keep from having a low valley like that, but if you go just let's say once every Friday then take 100mg test P on Wednesday to keep it up until your next long ester dose.
I don't have huge peaks and valleys and no problem with estrogen.
Now the other issue, I would highly suggest going to a specialists about that.