Trouble with high blood pressure medicine, unbearable side effects to all of them.

[Systemlord]

I'm having a difficult time with all blood pressure medicine, whether ACE inhibitors, beta blockers and Losartan to name a few off the top of my head. They all pretty much cause the same side effects, Losartan causes toenails to develop black horizontal lines (3 rows) on both toenails and on the skin in front of the toenails as well as dry damaged skin.

Losartan causes rashes, muscle spasms and cramping. The ACE inhibitors cause burns and softening of tissue under the roof of my mouth as well as burning in skin. I feel like death on beta blockers. The calcium blockers turned skin very red and damaged the skin.

The only thing that works great in the short term is a diuretic (12.5mg), I'm constantly struggling to keep potassium from falling below range and have to down potassium every couple of hours and even then it's a fight to maintain levels.

I can't restart TRT with blood pressure already out of control because my urination will cease (high BP and kidneys function) and I will have problems within days. My doctor is afraid to prescribe alpha blockers because he fears if side effects are encountered and I need to stop, he has fears that I could get a stroke.

My GP isn't willing to do anything about my 180 morning glucose or 250 glucose at night time since the Glipizide and Metformin had to be stopped do to side effects and is afraid the other options will suppress glucose too low. The Glipizide crashed my potassium and the metformin cause a sore throat, voice changes and a nasty cough.

I need options here, I feel like I'm in a deep mud pit and am unable to get out.

 

[Vince Carter]

So no alpha blocker use but Dr won't prescribe? If so it's pretty easy to get Doxazosin/Cardura from overseas in 1mg tabs.

 

[Systemlord]

So no alpha blocker use but Dr won't prescribe?

My GP goes silent when he is not willing to do anything, in a way he is saying will will do nothing. I believe as my glucose levels has increase, there seems to be a 1:1 ratio as my glucose levels increases, so to does my blood pressure.

I ask my GP to treat the diabetes and maybe the blood pressure will go down as a result of treating the diabetes. He said the Glipizide and Metformin are the go to for type 2 diabetes and the others are the heavy guns usually for much higher glucose levels, he fears these other option will suppress glucose too low.

They want me on TRT so that it will correct the high glucose, but controlling blood pressure is the major hurdle and urination will almost cease and problems develop quickly and ketones will be made within days.

I'm negative for ketones when not on TRT, days after restarting TRT high levels of ketones are present.

 

[Golfboy307]

Ouch, that does seem to be a tough case. You seem to imply that you have underlying kidney disease, which may be the cause of the high BP? Is that true? Any treatment options there?

 

[Systemlord]

Ouch, that does seem to be a tough case. You seem to imply that you have underlying kidney disease, which may be the cause of the high BP? Is that true? Any treatment options there?

It's the other way around, the high blood pressure is affecting the kidneys. My doctors are telling me kidneys are exceptionally strong and liver testing shows very good levels, kidney testing also shows good levels. It's almost like the T injection within the first day shuts down my kidneys because I started TRT with high blood pressure.

The last time I did a daily protocol, after the first week I never had blood pressure that good in years, I was hoping this time around things would be the same. It's getting past the first couple of weeks that is the hurtle.

The time I've spent on blood pressure medicine I have been urinating twice as much and is easier to empty my bladder and feel better, until the skin and rashes developed. It's clear the high blood pressure is affecting the kidneys negatively. The last year and a half on TRT I've had high blood pressure and I think it caught up with me.

If I can just get my blood pressure under control I can finally get back on track. I know there are potassium sparing drugs, I'm just worried I'll over respond to it like everything else. I could always carry around the other non-sparing potassium version of diuretic in case things get out of control.

I had to did just that with the Losartan, potassium was getting high and I took half the normal dosage of diuretic and things went the other way quickly. I'm headed towards kidney disease if I don't get this blood pressure under control.

 

[xqfq]

I'm not sure if it's applicable to your situation, but another option may be the mostly-cardio-selective beta blockers such as Bystolic (Nebivolol). I have read great things about them for certain types of hypertension. They don't have the side effects of the usual class of beta blocker medications.

 

[Systemlord]

I'm not sure if it's applicable to your situation, but another option may be the mostly-cardio-selective beta blockers such as Bystolic (Nebivolol). I have read great things about them for certain types of hypertension. They don't have the side effects of the usual class of beta blocker medications.

I was under the impression all beta blockers are the same, this is what my GP was saying. I don't trust him or his judgement. He's overly concerned with time limits on appointments, rushing the process eventually leads to mistakes.

 

[xqfq]

I was under the impression all beta blockers are the same, this is what my GP was saying. I don't trust him or his judgement. He's overly concerned with time limits on appointments, rushing the process eventually leads to mistakes.

Bystolic is more cardio selective than other beta blockers, meaning (hopefully) less side effects. I have read that it’s less cardio selective in higher doses, and some men require high doses to reduce BP. What is your BP right now?

I know Dr. Thomas O’Connor is a fan of it for some men on steroids and TRT. But it seems like BP meds are very individual. I think he’s a fan of it because it does not as strongly affect norepinephrine in the body, so strength / energy may not be as affected. But that’s my broscience guess- I have no idea here, I’m just giving an option I’ve read about..

You may want to consider a consult with someone like Dr. Thomas O’Connor, as your situation sounds complex and multi-factoral. He does Skype consults.

 

[SilverSurfer]

What about clonodine?

 

[T4lee]

Clonodine has worked well for me

 

[Systemlord]

Bystolic is more cardio selective than other beta blockers, meaning (hopefully) less side effects. I have read that it’s less cardio selective in higher doses, and some men require high doses to reduce BP. What is your BP right now?

I know Dr. Thomas O’Connor is a fan of it for some men on steroids and TRT. But it seems like BP meds are very individual. I think he’s a fan of it because it does not as strongly affect norepinephrine in the body, so strength / energy may not be as affected. But that’s my broscience guess- I have no idea here, I’m just giving an option I’ve read about..

You may want to consider a consult with someone like Dr. Thomas O’Connor, as your situation sounds complex and multi-factoral. He does Skype consults.

My BP before going on these BP meds was 169/100. The effects of the Losartan hasn't worn off yet. I'm limping along on 1/4 diuretic and I have been delt low potassium on more than one occasion in the last 24 hours.

If this low dose diuretic and high dose potassium doesn't work in my favor I may have to seek advice outside my provider as you have suggested.