ACE and ARB blood pressure meds (i.e losartan) and coronavirus concern

Buy Lab Tests Online
Skip to 23:33. This is troubling. Jay's guest, Anthony Jay, PhD, fails to mention the more recent contrarian argument that we've been making in which upregulation of ACE2 via ACEIs and ARBs can actually be protective and block the virus from entry (and the fact that Losartan is in clinical trials as potential treatment for COVID-19 [Losartan for Patients With COVID-19 Requiring Hospitalization - Full Text View - ClinicalTrials.gov]. He advises to just stop the meds even if BP goes up a little.
 
Defy Medical TRT clinic doctor
It’s the main offender of misinformation. People keep forwarding this information as of they just discovered a miracle. I keep getting all this virus stuff, It’s all BS. They know but the CDC has never heard of it?

******** is a menace to society in my opinion.

BTW: I’m on 50mg If it a day of it. Works well.

Done venting :)
 
Westin said:
It’s the main offender of misinformation. People keep forwarding this information as of they just discovered a miracle. I keep getting all this virus stuff, It’s all BS. They know but the CDC has never heard of it?

******** is a menace to society in my opinion.

BTW: I’m on 50mg If it a day of it. Works well.

Done venting :)
Click to expand...
Oh, gotcha. I’m mostly on message boards, rarely on ********. But I agree, mostly sensationalism and misinformation (and possibly disinformation!!!).
 
Much of the controversy about the positive or negative effect of ARB/ACEI is based on a time confusion. The positive effect of ACE2 would only occur AFTER the SARS-CoV-2 entered into the target cells. On the opposite, BEFORE its entry, the ACE2 availability may potently increase the number of receptors for the virus spike proteins and leads to an enhanced severity of the infection. This is the conundrum I worry about. What we urgently need now is the ratio of death according to the use or not of ARB/ACEI among the patients with comorbidities (hypertension, diabetes, CVD).
 
“Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% CI 0.128-0.916, p=0.025). The meta-analysis showed that ARB use has positive effects associated with morbidity and mortality of pneumonia. Interpretation Elderly (age>65) COVID-19 patients with hypertension comorbidity who are taking ARB anti-hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti-hypertension drugs.”
www.medrxiv.org

Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients

Background The novel coronavirus (CoV) severe acute respiratory syndrome (SARS)-CoV-2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countries. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor. Indeed, it was reported...
www.medrxiv.org www.medrxiv.org
 
Golfboy307 said:
Excellent balanced article. Thanks for posting. I am going to keep taking my 20mg Lisinopril for the time being. And social distancing!
Click to expand...
Same here as I’m on telmisartan. I also wonder if taking these drugs causing an increase in ACE2 receptors, how long does it take for the new Receptors to go away when the drug is discontinued? Processes like that aren’t instant, correct?
 
Buy Lab Tests Online
Defy Medical TRT clinic

Share this page

Sponsors

bodybuilder test discounted labs
cheap enclomiphene
TRT in UK Balance my hormones
Discounted Labs
Testosterone Doctor Near Me
Testosterone books nelson vergel
Register on ExcelMale.com
Trimix HCG Offer Excelmale
BUY HCG CIALIS

Online statistics

Members online
7
Guests online
10
Total visitors
17
Totals may include hidden visitors.

Latest posts

© Copyright ExcelMale
Top