Article
Over 10-15 years ago there were several progressive doctors in the cash HRT/TRT (hormone replacement therapy/testosterone replacement therapy) space who at some point realized subcutaneous administration of testosterone cypionate or enanthate not only absorbed as effectively as IM (intramuscular injections). They also found that more frequent subcutaneous (SC) injections yielded more stable levels than once per week IM injection. Some of these doctors started writing about it including TRT expert Dr. Eugene Shippen who wrote the book “The Testosterone Syndrome.” These doctors may have also found old studies (or did small observational studies themselves) showing that oil-based hormone injections can be administered SC with efficacy.
Over the years as TRT became more prevalent, experts and physicians have attempted to develop novel ways to administer testosterone. This lead to more formal studies being done on the effects of subcutaneous testosterone injections.
In addition to formal studies, many progressive doctors also experimented and observed that SC delivery is equal if not superior (in pharmacokinetics) over single larger dosed IM injections.
Subcutaneous testosterone injections may also present lower Cmax levels of testosterone (peaks), which could translate into fewer problems with increased blood viscosity, blood pressure, and cardiovascular risks related to increased red blood cell volume (hematocrit).
Subcutaneous testosterone injections have been found effective by the FDA. They approved Xyosted for that purpose.
Its pointless trying to talk sense to these guys
@madman and
@Cataceous
If they get a study that says the sky is red, its red. Doesnt matter what everyones eyes are seeing.
You this same idiot.
Your very first post
(DEC 8/2019) on Excel!
You were hurt from the get-go.....LMFAO!
There is a fair bit of speculation that this is the case. Moreover, with scrotal cream DHT can get very high, which also counteracts estradiol, both in creation and in receptor binding. Interesting. In theory I see how it should counteract the creation. However, my labs just came back on the...
www.excelmale.com
your post #36
I am self medicating "TRT". I simply started at 80mg as kept increasing every 6 weeks by 20mgor so until I reached 200-250mg which is where I feel well. I have also experimented similarly with subq (a waste of time for me) and shallow IM (excellent, man up and do it). Also with dosing E2d, e3.5d and weekly.
Im using pharma Cyp procured through a friendly pharmacy. Have never tested T, FT or E2, but I feel fantastic. Did put on water weight in the beginning even with the small dose, but that went away.
Not using an AI, and feel like a million bucks. HCG made no difference either way really so I dropped it.
Age 31, and my main motivation for continuing is the supreme confidence gained as well as the "aggression" which is really useful when negotiating in the business world. People simply dont mess with me anymore! Im pretty sure high E2 is a factor here. Ever tried to win a fight with a chick who has PMS? Well, with high E2 no one will mess with you either. Im dead serious here.
To all those not "dialed" in after so many years of posting, call it a "mild cycle" if you insist, but you have to trial 200 or 250mg\week IM EOD for just a month and revert back. You may just be amazed!
And yes, I jumped over 200mg after reading all the hype created by a certain you know who.
------------------------------------------------------------------------------------------------------
You stated.....
I simply started at 80mg as kept increasing every 6 weeks by 20mgor so until I reached 200-250mg which is where I feel well.
My reply:
80 mg.....6 weeks later 120 mg.....6 weeks later 140 mg.....6 weeks later 160 mg.....6 weeks later 180 mg.....6 weeks later 200 mg.....6 weeks later 220 mg.....6 weeks later 240 mg.
40 weeks later.....really? Yes, we can shorten this some as you did state....."
I simply started at 80mg as kept increasing every 6 weeks by 20mgor so until I reached 200-250mg which is where I feel well"
How can you even state.....
"200-250mg which is where I feel well".....as you never gave your body a fighting chance to see how you truly feel on the said protocol (T dose/injection frequency)..... you changed your dose every 6 weeks which is nowhere near enough time to truly gauge such.
As not only did you not have blood work done to see where your TT/FT and e2 levels sit but you kept upping your dose every 6 weeks and as you should know whenever one starts trt or is tweaking dose (increasing/decreasing) blood levels will be in FLUX during the following weeks leading up until when they have stabilized at 5-6 weeks and even then once levels have stabilized one would need to give it 2-3 months at new said T levels to not only allow the body to adjust to those new levels.....but to truly gauge how one feels overall regarding mood/energy/libido/erectile function/body composition/recovery.
6 weeks on the said protocol (T dose/injection frequency) would in no way be enough time to state whether the TT/FT /e2 levels achieved truly result in the overall improvement in low-t symptoms.....let alone overall well-being.
You stated.....
Have never tested T, FT or E2, but I feel fantastic.
My reply:
That sounds like a sensible approach! No one could truly gauge a protocol (T dose/injection frequency).....let alone state they feel best at such T dose.....changing T dose every 6 weeks.....top it off with the fact that you have never tested your TT/FT/e2.....let alone the effects such levels have on your blood markers.
Just to be clear.....yes some men may very well need 200 mg/week or slightly higher to achieve a healthy FT level but needing such a dose is not common for many men on trt.
Although symptom relief is what truly matters lab work is critical as not only do we want to know how said protocol (T dose/injection frequency) affects ones TT/FT levels but also to keep an eye on the impact it has on overall blood markers as we are not only trying to relieve/improve symptoms of low-t but to minimize/avoid any potential negative effects on overall health especially long-term.
Regarding reference ranges, they are not set in stone and should be used as a guideline to give us an idea of where hormones/blood markers sit as levels could very well be too high or low resulting in negative effects.
*There is nothing wrong with one running TT/FT level above range as long as blood markers are healthy and you feel well overall.
No one is saying you have to keep your levels in a set range as the goal is to achieve the beneficial effects of having healthy FT levels while making sure overall health is maintained long term.
If you feel great on such a dose then stick to your protocol but you should not be self-treating yourself blindly by avoiding blood work.
It is naive for you to go on claiming you feel great at such dose when you never gave your body a FIGHTING CHANCE because you were changing your dose every 6 weeks.....it is misleading.
This has been stated numerous times on the forum.....many are struggling because they are changing protocols (T dose/injection frequency) way too soon.....let alone in many cases changing too many things at once (use of an aromatase inhibitor/hCG).
Your post #61
I really dont have years to do such testing and wait 2-3 months between changes and spin my wheels like most others seem to do. I needed solutions NOW, and a solution I have found!
As you said many others are struggling by changing doses too often. Why mention that? I am having the time of my life!
My reply post #63
You clearly missed the point on this one!
Your levels were in FLUX the majority of the time.....
you have no clue how you would feel on a lower dose.....every 6 weeks you upped your dose..... then go on and state you feel great at such dose.....seriously.
Would in no way take years if you had any sense in your head.
This is coming from a guy who
upped his dose every 6 weeks.....
spent months on end in FLUX only to go on and
state that once he reached such dose he feels great.
Then he one-ups the complete s**t show by stating.....
" To all those not "dialed" in after so many years of posting, call it a "mild cycle" if you insist, but you have to trial 200 or 250mg\week IM EOD for just a month and revert back. You may just be amazed!
4 weeks.....
.....you f***ing amateur!
Nothing but a stink coming out your piehole!
Stick to those bro forums.....BRUH!
