madman
Super Moderator
Since what I referring to is purely speculative and I haven't heard anyone else taking about it, doses and timing have to be guesswork. I don't remember what Dr. Denmeade's intervals are but I seem to recall that his dose was 600mg, although I could be way off. Anyway, if I was going to try the periodic burst technique as a preventative, I would go with 600mg of proprionate once every two or three months, but that is purely a guess. That said, and anti-cancer protocol is always step one, and a preventative protocol would be fairly hard to test in a trial so we are likely far off from having good data.
Dr. Denmeades protocol is 400 mg TC every 4 weeks which has also been trialed every 7 weeks.
Pointless for one already on T-therapy to even waste their time trialing a periodic burst technique as a preventative measure when all that truly matters is having a healthy FT level which would be achieved using therapeutic doses of T.
Even than although TP could replace TC for BAT your T levels are going to drop off much faster at the 2 week mark vs TC due to the PK and highly doubtful one could get away with using TP every 2 let alone 3 months!
Using TC every 7 weeks is already stretching it.
Better plan on using an AI too with that whopping dose of T!
Even than when it comes to T-therapy that outdated protocol 200 mg TC/TE every 2 weeks still being pushed by those clueless endos is far from optimal as it would have one being back to hypogonadal before their next injection due to the PKs.
Sure some men may still fare well on such but it is far from optimal not only due to the rollercoaster effect where T levels are sky-high off the hop only to be followed by much lower levels come day 10-14 which can easily have a negative impact on ones mood, energy, libido and erectile function let alone you will not be getting/taking advantage of the full anabolic benefits of T (increase muscle, strength, enhanced recovery).
The video presented a treatment called Bipolar Androgen Therapy (BAT) for prostate cancer, in which patients are given high doses of testosterone to resensitize the cancer to hormone therapy. Dr. Sam Denme discussed the concept, results from trials, and future research, highlighting the potential of BAT to improve survival, and quality of life, and resensitize cancer to hormone treatments. The talk also addressed the challenges and potential risks associated with BAT, as well as the need for further studies and funding to explore different...
- madman
- prostate cancer; bat; testosterone; adt
- Replies: 36
- Forum: Prostate Related Issues
Loved this one!
True Warrior!
“If we continue to do the same things, we will get the same results.”
“If BAT can be used to sensitive Xtandi/darolutamide ad infinitum, prostate cancer becomes a treatable condition like diabetes.” – Russ Hollyer
Meeting Summary
Advanced prostate cancer patients who are failing the standard hormone (androgen) deprivation therapy (“castrate resistant”) are interested in finding new options. Bipolar Androgen Therapy (BAT, where high doses of testosterone are alternated with androgen...
True Warrior!
“If we continue to do the same things, we will get the same results.”
“If BAT can be used to sensitive Xtandi/darolutamide ad infinitum, prostate cancer becomes a treatable condition like diabetes.” – Russ Hollyer
Meeting Summary
Advanced prostate cancer patients who are failing the standard hormone (androgen) deprivation therapy (“castrate resistant”) are interested in finding new options. Bipolar Androgen Therapy (BAT, where high doses of testosterone are alternated with androgen...
- madman
- prostate cancer; bat; testosterone; adt
- Replies: 23
- Forum: Prostate Related Issues
Russ Hollyer's self-experimentation protocol was 400 mg TP every 4 weeks.
Continually uses an AI during the T spike phase to control estradiol followed by use of an estrogen patch to replace systemic estradiol during the ADT/castrate phase!
* Russ has advanced prostate cancer, Gleason 9, and was diagnosed in 2018. He had a radical prostatectomy (RP) later that year, estrogen/Zytiga ADT in 2019, followed by high testosterone, followed by do it yourself BAT. Each BAT treatment involves the self-administration of hormonal ablation or hormonal extremes.
post #27 (Go nuts!)
Hot of the press you heard it here first at Nelson's domain!
*the high dosed testosterone that we use for these studies is generic there's no commercial sponsors so none of these studies is influenced by any pharmaceutical companies
*the high dosed testosterone that we use for these studies is generic there's no commercial sponsors so none of these studies is influenced by any pharmaceutical companies
- madman
- pca/psa; testosterone; bipolar androgen therapy
- Replies: 26
- Forum: Prostate Related Issues