Pressure headaches, can it be test Cyp

[MikeDaly1970]

Guys recently started on test cyp, am on .25ml (50mg) twice week.... all seems ok, except around same time started to get what I describe as pressure headache around back side and front head, eyes strain.
Thing is when I wake in the mornings I feel fine, it's always mid afternoon or evening it comes on, regardless of working or sitting on couch all day
Do you think it could be to do with the test cyp?

Other than that I've no clue

Any advice, thanks all

 

[Systemlord]

I describe as pressure headache around back side and front head, eyes strain.
Thing is when I wake in the mornings I feel fine, it's always mid afternoon or evening it comes on, regardless of working or sitting on couch all day

Do you think it could be to do with the test cyp?

Welcome to ExcelMale @MikeDaly1970.

The majority of the time TRT is exacerbating an unknown medical condition, vitamin or mineral deficiency or you're overdosed beyond your natural setpoint for hormones.

In your case you just started TRT and the weeks long road to shutting down your natural production.

You're changing your hormone landscape and it's going to take some time for your body to adjust.

Typically it takes 4-6 weeks to reach steady blood levels.

There are bound to be side effects just starting out.

 

[MikeDaly1970]

Welcome to ExcelMale @MikeDaly1970.

The majority of the time TRT is exacerbating an unknown medical condition, vitamin or mineral deficiency or you're overdosed beyond your natural setpoint for hormones.

In your case you just started TRT and the weeks long road to shutting down your natural production.

You're changing your hormone landscape and it's going to take some time for your body to adjust.

Typically it takes 4-6 weeks to reach steady blood levels.

There are bound to be side effects just starting out.

My apologies, I must explain,


Beofre starting test Cyponiate, I was on nebido for 4 years, so i am not just starting TRT.

I stopped nebido 5 weeks ago, my T at the time was 344ngdl , went on test cyp then,

my haemoctric 5 weeks ago was .54, reduced to .47 after 1 pint blood donation (pressure headaches stopped)

My doc put me on test cyp .4ml x twice week (160mg), headaches come back, then o reduced down to 100mg , .25ml = 50mg x twice week.

Last week had my bloods done, below is results, 37nmol = 1067 ng/dl

This 1067ngdl is levels one hour prior to my next injection, which I'm sure has my t reaching maybe 1600ngdl, can this be the cause of the pressure headaches.

Plus, my haemocrat is back from .47 to .51 within the 6 weeks after i donated, this I'm sure is down to too high a level of T.

Should I drop my testosterone to say .2ml (40mg) twice week, and will that help restore the above to healthier levels, I.e. drop haemocrat back from .51, and maybe drop my T level to about 780 ngdl a few hours prior to next Injection, or what level do you think is ok to be at right prior to next injection

See attached photos

Thanks guys

 

[sammmy]

Your WBC seem elevated due to elevated Neutrophils - compare with your values from before the headaches started. If there is an elevation, this suggests some kind of infection going on - possibly bacterial because Lymphocites are not elevated.

Headaches manifest in afternoon or evening because the immune system is more active at those times.

Observe if your headaches appear certain time after meals - skip meals in afternoon/evening to check that. If they are related to meals, that would suggest an intestinal bacterial infection.

Also observe if your headaches appear after injection doses.

 

[Cataceous]

If you're looking for anecdotes, I had this type of headache ramp up after starting TRT. The progression was slow enough that I didn't make the connection until much later, when I had greatly reduced the dose, and the headaches finally went away. For me even ~65 mg/week testosterone enanthate was too much. This yielded pretty constant TT of about 800 ng/dL What works for me now is daily injections of a blend of 2.4 mg testosterone propionate and 3.2 mg testosterone enanthate. This yields daily peak TT of 700 ng/dL and a trough in the low 400s.

 

[Belekas]

Absolutely it can. When I was running 250mg/week(not TRT) for training purposes, did that for 3 years straight, I was having damn headaches pretty much everyday. But I also had other blood markers elevated that showed I had issues going on that needed fixing and most likely was the cause or contributting to it. Now off TRT for 8 months and headaches are a rare thing considering I follow my blueprint and not deviate from it. Honestly to be able to figure it out- context is all that matters. Hydration, food, sleep, stress, other drugs, BP, BG and so on.

 

[Seagal]

I would measure my blood pressure to check if T has impact on that and might be a reason for the headache.
You could reduce the T peaks further by going from 2x to 3x per week injections.

Your ferritin is now low, probably due to blood donation and the following regeneration of hematocrit.

 

[MikeDaly1970]

I would measure my blood pressure to check if T has impact on that and might be a reason for the headache.
You could reduce the T peaks further by going from 2x to 3x per week injections.

Your ferritin is now low, probably due to blood donation and the following regeneration of hematocrit.

Can I do anything for ferritin to increase, or will it naturally and is it ok to just let it do that

 

[Seagal]

Can I do anything for ferritin to increase, or will it naturally and is it ok to just let it do that

The iron you get with your nutrition should eventually increase ferritin. You could take an iron supplement to support that. Around 100 is a good value.
I recently checked my ferritin and it was 75. I now take an iron bisglycinate supplement. Low ferritin might cause symptoms similar to hypothyroidism i.e. fatigue, hair loss etc.

 

[Cooper]

Absolutely it can. When I was running 250mg/week(not TRT) for training purposes, did that for 3 years straight, I was having damn headaches pretty much everyday. But I also had other blood markers elevated that showed I had issues going on that needed fixing and most likely was the cause or contributting to it. Now off TRT for 8 months and headaches are a rare thing considering I follow my blueprint and not deviate from it. Honestly to be able to figure it out- context is all that matters. Hydration, food, sleep, stress, other drugs, BP, BG and so on.

I must have missed it in another post somewhere but can you say why you stopped TRT and what you did to stop? How are you feeling now?

 

[Belekas]

I must have missed it in another post somewhere but can you say why you stopped TRT and what you did to stop? How are you feeling now?

I have a big journal/thread if you do a search on my username where I've documented all my TRT journey. Stopped because of different side effects. Was on 100mg/week split E3.5D for 3-4 months and then the remaining 8-9 months was trying higher and lower to find a sweetspot where I get least sides and able to function well without adding more pharmacologicals. Had some good weeks but overall felt terrible. Quit cold turkey 8-9 months ago after 12 months on. Def should have done PCT as felt ruff more less over the months in non linear fashion. Now feeling a lot better, cool, calm and collected. BP came down to great levels, RHR, no more red face/neck. No more random BP spikes, headaches, pressure in head, etc. Feeling relaxed, no more being wired all day long. The libido and EQ took a hit but seems they have recovered by now or at least started to significantly. But I'm also working on myself 24/7/365 so that also can be a byproduct of getting healthier. Taking no supplements at all, no vitamins, no minerals, no antioxidants, nada, just eating what I know is good for me. Feel free to ask or/and check out my thread/journal.

Regards,
bel

 

[Wolverine]

If you're looking for anecdotes, I had this type of headache ramp up after starting TRT. The progression was slow enough that I didn't make the connection until much later, when I had greatly reduced the dose, and the headaches finally went away. For me even ~65 mg/week testosterone enanthate was too much. This yielded pretty constant TT of about 800 ng/dL What works for me now is daily injections of a blend of 2.4 mg testosterone propionate and 3.2 mg testosterone enanthate. This yields daily peak TT of 700 ng/dL and a trough in the low 400s.

Cat: What gauge and length of needle do you use for everyday injections and where do you inject? Tx

 

[Cataceous]

Cat: What gauge and length of needle do you use for everyday injections and where do you inject? Tx

31 gauge, 5/16", subcutaneous, mostly around the waist.

 

[MikeDaly1970]

Guys, can I ask, I want to see what my Testosterone numbers are at peak, so....

Let's say I take. 3ml (60mg) once a week.

Let's say I inject Cyponiate .3ml (60mg) on a Monday morning when do you think it peaks so I can get bloods done?

My guess is, as i take it weekly, would I peak at maybe 3.5 days or thereabouts, if that's the case then get bloods done on Thursday morning?

Thanks guys

 

[Systemlord]

My guess is, as i take it weekly, would I peak at maybe 3.5 days or thereabouts

More like 12-18 hours. The peaks aren't very useful, because you can get a 2000+ level that lasts very briefly not really giving you value info of where your levels are at the majority of the time.

The midpoint and trough levels are more valuable.

 

[madman]

Guys, can I ask, I want to see what my Testosterone numbers are at peak, so....

Let's say I take. 3ml (60mg) once a week.

Let's say I inject Cyponiate .3ml (60mg) on a Monday morning when do you think it peaks so I can get bloods done?

My guess is, as i take it weekly, would I peak at maybe 3.5 days or thereabouts, if that's the case then get bloods done on Thursday morning?

Thanks guys

The half-lifes of TE/TC are basically interchangeable.

When using exogenous esterified TE/TC there will be an initial burst release as T levels start rising within the first few hours post-injection and Tmax will be achieved in 8-12 hrs much faster than many would think.

T levels will be high post-injection (peak/during the first few days) as once Tmax is achieved levels decline gradually over the following days.

Even then it is much easier to test true trough which is just before your next injection.

I have an older paper from Dr. Swerdloff in which he states TE peaking 6 hrs post-injection (data not shown).

Sift through the literature and look up the Nieschlag/Behre PK studies TE (Tmax) was shown to be anywhere from 8-24 hrs.

Keep in mind many of the PK studies never had blood sampling drawn hourly!

Look over the Antares Xyosted (TE Auto-injector)) study and that is using strictly subcutaneous injections which had TE (Tmax) 10 hrs post-injection.

 

[madman]

Guys, can I ask, I want to see what my Testosterone numbers are at peak, so....

Let's say I take. 3ml (60mg) once a week.

Let's say I inject Cyponiate .3ml (60mg) on a Monday morning when do you think it peaks so I can get bloods done?

My guess is, as i take it weekly, would I peak at maybe 3.5 days or thereabouts, if that's the case then get bloods done on Thursday morning?

Thanks guys

Where does your SHBG sit?

You never even had the most critical blood marker free testosterone tested!

Although TT is important to know FT is what truly matters as it is the active unbound fraction of T responsible for the positive effects.

You are hitting a very high trough TT 1037 ng/dL which means that your trough FT would be high-end/high!

As you would know your peak TT, FT and estradiol will be higher!

This is on your current protocol 100 mg TC split twice-weekly (50mg every 3.5 days).

Your doctor clearly had no clue what he was doing throwing you on 160 mg TC split twice-weekly (80 mg every 3.5 days) off the hop which would have had your trough TT and more importantly trough FT absurdly high!

Standard starting dose TC/TE is 100 mg T/week or better yet 50 mg twice-weekly (every 3.5 days).

Luckily your dose was dropped but keep in mind you would still be hitting a high-end/high trough FT which can easily drive up your hematocrit!

You need to know where your trough FT sits!

 

[MikeDaly1970]

He has now cut me down to .3ml (60mg) once a week.....

He says he put me on the 160mg (.4ml x Reece week) jus to push up my levels as I was 230ngdl prior to 1st injection, I dunno maybe that's just his excuse for putting me on such a high dose

Either way, I am now on .3ml (60mg) once a week, so all your comments guys, I'm gonna give it a few weeks an test trough level before next injection an see where it sits

Thanks all

 

[Systemlord]

He has now cut me down to .3ml (60mg) once a week.....

Your doctor is grossly inexperienced in prescribing testosterone! Your testosterone levels are going to be abysmally low at the end of the week on 60 mg once a week!

Your doctor is flinging noodles at the wall and seeing what sticks, he doesn’t have a clue what he’s doing.

 

[MikeDaly1970]

Apologises, this should read, .225ml once a week is 50mg weekly