Pregnenolone Supplementation in Men: Experiences and Dosage Considerations

[Nelson Vergel]

Users on ExcelMale.com shared their experience with pregnenolone supplementation, providing insights into dosage and effects. Here's a summary of the key points:

Dosage and Effects​

• Optimal Dose: The user found benefits at 100mg, including higher libido, more pronounced nighttime erections, and better sleep1.
• Inconsistent Results: While 100mg seemed effective, the results were not consistent over time1.
• Diminishing Effects: Continuous daily use of 100mg led to waning effects by the second day1.
• Lower Doses: Experiments with 10mg, 25mg, and 50mg doses were less effective, with extended use leading to negative effects1.

Observations and Theories​

• Progesterone Levels: The user theorized that the diminishing effects might be due to elevated progesterone levels1.
• Pregnenolone vs. Progesterone: Direct progesterone supplementation was found to be less beneficial and more likely to cause negative effects compared to pregnenolone1.

Questions for Further Research​

The user sought clarification on:

1. The half-life of pregnenolone
2. The half-life of pregnenolone's sulfate derivative
3. The conversion rate of pregnenolone to progesterone
4. Optimal dosing frequency1

This summary highlights the complexity of pregnenolone supplementation and the need for individualized approaches. More research is needed to fully understand the optimal use of pregnenolone in men.

Citations:​

1. Help determining proper pregnenolone dosage and frequency
2. Help determining proper pregnenolone dosage and frequency

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Answer from Perplexity: https://www.perplexity.ai/search/sc...IInU9o54TEi30F0Y9JdvAw?utm_source=copy_output