Appreciate the in-depth response.
Although many of Centeno's patients inquire about BPC-157, he remains skeptical of peptides in general mainly due to his past fight with the FDA over his clinic's PRP/stem cell protocols which made him skittish about adding compounds that have, at best, only anecdotal reports and no human studies as of yet.
I talked to my local Regenexx clinic doc and mentioned that I use peptides and he confirmed the above re Dr. C. He further mentioned that one of the Regenexx clinics in the south has started to use BPC-157 with some of the patients, so Dr. C knows the mounting positive anecdotes have to mean something and I believe it is only a matter of time that he will come around the bend.
The word peptide refers to collections of amino acids that are joined together by chemical bonds. In orthopedics, peptides have been increasing in mainstream popularity. Specifically, a peptide known as Body Protection Compound 157 or BPC 157 has been touted to accelerate tissue healing.
newregenortho.com
Regenexx offers non-surgical, regenerative orthopedic treatment options for pain related to osteoarthritis, joint injuries, overuse conditions, spine pain, and common sports injuries.
regenexx.com
CRP is a nonspecific inflammatory marker, so it is anyone's guess what the etiology(s) could be. First things come to mind in addition to possible food sensitivities - hypertension and SIBO. Unfortunately, there are no food sensitivity diagnostics I know of that are reliable and that yield any consistent reproducibility, let alone utility on which to base an actionable protocol, as most of the methodology is based on the IgG delayed food sensitivity model whereby elevated IgG antibody levels have been debunked as normal, non-pathologic responses in recent years.
I agree that the ortho pre-op milieu is rarely ever addressed, except with cutting-edge docs like Dr. Yurth who has made that very clear in many YouTube videos. I considered seeking her out for my MSK issues, however, the distance logistics would make it inconvenient since I would have to travel back and forth each time I need immediate follow up care first-hand.
For me, the two biggest issues in stem cell therapy I am still somewhat skeptical of are:
1) harvesting BMAC MSCs from patients >50. Considering cellular senescence increases over time, could this cancel the benefits of stem cell therapy? This is the marketing tool that the clinics promoting non-autologous stem cells products (i.e. birth tissue) use against autologous (bone marrow/adipose tissue) stem cell harvesting. Dr. C address that
here.
2) Regenexx does what's called a viability test of the harvested MSCs which is good. But, here in the States, we are limited by a finite number of those cells, as it is not legal to use cultured MSCs since it would be considered a drug product. That's why Regenexx has what's called Regenexx-C which is only offered outside the U.S., in the
Caymans. The cost starts at $20K and goes up from there. Not an option for most folks, except for the affluent few that like to travel to do their medical procedures.