only happy when estradiol is VERY low

[ggenovez]

Hi All,

I've been on TRT for a few years. I've never felt AWESOME more like a little better than before. I started experimenting with my dosage and I noticed my energy went up the more AI inhibitor I took. When I got to .5g/day of anastrazol, I felt AWESOME!!! full of energy, not waking up 2-3 times per night to urinate... of course with a dose so high my estrodial is SUPER low. sub 5 in a range of 7.6-42.6 pg/mL

Has anyone else run into this? any thoughts?

 

[JA Battle]

Hi All,

I've been on TRT for a few years. I've never felt AWESOME more like a little better than before. I started experimenting with my dosage and I noticed my energy went up the more AI inhibitor I took. When I got to .5g/day of anastrazol, I felt AWESOME!!! full of energy, not waking up 2-3 times per night to urinate... of course with a dose so high my estrodial is SUPER low. sub 5 in a range of 7.6-42.6 pg/mL

Has anyone else run into this? any thoughts?

WhT is your shbg?

 

[DixieWrecked]

Hi All,

I've been on TRT for a few years. I've never felt AWESOME more like a little better than before. I started experimenting with my dosage and I noticed my energy went up the more AI inhibitor I took. When I got to .5g/day of anastrazol, I felt AWESOME!!! full of energy, not waking up 2-3 times per night to urinate... of course with a dose so high my estrodial is SUPER low. sub 5 in a range of 7.6-42.6 pg/mL

Has anyone else run into this? any thoughts?

How high is your TT and your FT?

How's your libidio and erections?

 

[ggenovez]

SGHB 16.1 noml/l
TT 644 ng/dL
FT 22.2 pg/mL

Libido and erections vary with the anastrazol intake. IF it's @ 3.5g / week then its AWESOME. Otherewise not so much.

 

[JA Battle]

SGHB 16.1 noml/l
TT 644 ng/dL
FT 22.2 pg/mL

Libido and erections vary with the anastrazol intake. IF it's @ 3.5g / week then its AWESOME. Otherewise not so much.

I remember a member named Vince Carter who reported having felt better with single digit e2.
he was also a low shbg patient. Low shbg means higher free e2 and higher free dht.

 

[Gman86]

That’s interesting that u wake up less to urinate with the higher dose. U would think it would be the opposite due to ur body shedding more water compared to higher E2 where it would hold more water. I always find when I increase my ai dose I pee more

Do u workout at all? Curious if u’ve noticed any body changes, such as looking leaner with the higher doses, for example

So is it safe to say 3.5mg/ week is ur sweet spot and what u’ll be sticking with? What’s the rest of ur protocol look like?

 

[Gman86]

Was looking through some notes and I have this one guys anecdotes saved. He takes 2mg/ week of ai and his E2 is <15, but he feels amazing. Here’s what I have saved

Been on this exact protocol 3 months. Since he started TRT
-120mg test/ week in one injection per week
-500iu’s HCG/ week (2 injections per week)
-2mg of anastrozole/ week
HIS EXPERIENCE
2 weeks I could feel it (placebo maybe), 4 weeks you couldn't get me out of the gym...I'm at 12 weeks now, still feel amazing
TOTAL T - 985
E2 <15
E2 85 before ai
-no more man periods, feels great, and the wife is happy too
-it is tanked(<15), but I feel amazing
I ASKED HIM HOW LIBIDO WAS WITH E2 <15
His response: yeah, wife says I'm 25 again

 

[Gman86]

I’m currently experimenting with raising my ai dose, so I’m really curious about ur experience. I feel like overall I’m feeling better since experimenting with an ai again, but I think it’s too early to make any conclusions or anything. But anyways, did u notice any improvements with ur testicles hanging better, or possibly being a little more full, or ur penis hanging better while flaccid during ur experimentation with higher doses of ai?

 

[ggenovez]

That’s interesting that u wake up less to urinate with the higher dose. U would think it would be the opposite due to ur body shedding more water compared to higher E2 where it would hold more water. I always find when I increase my ai dose I pee more

Do u workout at all? Curious if u’ve noticed any body changes, such as looking leaner with the higher doses, for example

So is it safe to say 3.5mg/ week is ur sweet spot and what u’ll be sticking with? What’s the rest of ur protocol look like?

so the problem on high E2 is I can't empty my bladder completely. Its full but all I can do is get a trickle out. that's why I wake up several times a night if I'm not on high AI

I'm taking .12 ml of 200 mg/ml daily so 168 mg / week.
HCG 500iu SQ BIW
Testosterone 50mg/ml cream - 2 clicks to scrotum AM

I do workout. But I've recently found this epiphany and when I told my nurse about it she said it was too high of a dose and instructed me to lower my dose.

I feel like ass.

So I'm just trying to figure out if this is normal or I should see a specialist or something else.

Gman, what I did was create a spreadsheet. and every day I would put my mood, libido, amount of sleep (on high dose I would get 6-7H and feel great on low dose I would get 9-10 H and feel aweful waking up.), morning erection, evening erection and any thing else I could thing about. Then I would start a protocol say .5g 3x a week. I could literealy see differences the following day, and by day 3 I would feel miserable again. then 4x a week and so on and so forth. but track any changes and you will see a pattern.

 

[Gman86]

so the problem on high E2 is I can't empty my bladder completely. Its full but all I can do is get a trickle out. that's why I wake up several times a night if I'm not on high AI

I'm taking .12 ml of 200 mg/ml daily so 168 mg / week.
HCG 500iu SQ BIW
Testosterone 50mg/ml cream - 2 clicks to scrotum AM

I do workout. But I've recently found this epiphany and when I told my nurse about it she said it was too high of a dose and instructed me to lower my dose.

I feel like ass.

So I'm just trying to figure out if this is normal or I should see a specialist or something else.

Gman, what I did was create a spreadsheet. and every day I would put my mood, libido, amount of sleep (on high dose I would get 6-7H and feel great on low dose I would get 9-10 H and feel aweful waking up.), morning erection, evening erection and any thing else I could thing about. Then I would start a protocol say .5g 3x a week. I could literealy see differences the following day, and by day 3 I would feel miserable again. then 4x a week and so on and so forth. but track any changes and you will see a pattern.

When u say low dose, like when u got 9-10 hours and felt like crap, what dosage are u referring to?

So u feel like ass currently? What dosage is the nurse making u currently take?

Are u taking 500 or 1000iu’s of HCG total per week?

Did u notice urself look any leaner on the higher ai doses? Jw if shedding water weight was visible in the mirror for u or not

 

[Gman86]

@ggenovez so would u say that 3.5mg/ week is ur sweet spot, and the dose u would like to take indefinitely if it were up to u?

 

[DixieWrecked]

How do your joints and bones feel? Any pain?

 

[Vince]

How do your joints and bones feel? Any pain?

That would be my concern, bone and joint issues. Osteoporosis

 

[Vince]

Estrogen deficiency can lead to excessive bone resorption accompanied by inadequate bone formation. Estrogen deficiency increases the number of osteoclasts and decreases the number of osteoblasts resulting in overall bone resorption.

answers
What is the role of estrogen deficiency in the ... - Medscape

Osteoporosis: Practice Essentials, Background, Pathophysiology

Osteoporosis, a chronic, progressive disease of multifactorial etiology (see Etiology), is the most common metabolic bone disease in the United States. It has been most frequently recognized in elderly white women, although it does occur in both sexes, all races, and all age groups.

www.medscape.com

 

[ggenovez]

When u say low dose, like when u got 9-10 hours and felt like crap, what dosage are u referring to?

So u feel like ass currently? What dosage is the nurse making u currently take?

Are u taking 500 or 1000iu’s of HCG total per week?

Did u notice urself look any leaner on the higher ai doses? Jw if shedding water weight was visible in the mirror for u or not

the lower dosage of AI, less than 3.5g/w, I would sleep 10H and feel like crap. At 3.5G/w I'm full of energy and don't have any problems waking up with 6-7h of sleep.

I was just moved to exemestane 25mg tabs. 1/2 tab 3x / week. I feel like ass. just sent in new blood work and I'm waiting. doubled my dose 1 day per week and that makes it tolerable. but nothing like my previous regimen.

I went from looking for a small country to conquer to looking for the early bird special.

1000 IUs/week

I did not notice getting leaner on the higher dose but I was on it for about 2 weeks when I started running out of pills and had to call for a refill and the whole thing came crashing down. That being said, with the energy I had, I think getting leaner would not be an issue. When you go from dragging ass to being on speed, there's a lot of things that happen.

As for joint and bone issues, nothing out of the norm for myself.

 

[Gman86]

the lower dosage of AI, less than 3.5g/w, I would sleep 10H and feel like crap. At 3.5G/w I'm full of energy and don't have any problems waking up with 6-7h of sleep.

I was just moved to exemestane 25mg tabs. 1/2 tab 3x / week. I feel like ass. just sent in new blood work and I'm waiting. doubled my dose 1 day per week and that makes it tolerable. but nothing like my previous regimen.

I went from looking for a small country to conquer to looking for the early bird special.

1000 IUs/week

I did not notice getting leaner on the higher dose but I was on it for about 2 weeks when I started running out of pills and had to call for a refill and the whole thing came crashing down. That being said, with the energy I had, I think getting leaner would not be an issue. When you go from dragging ass to being on speed, there's a lot of things that happen.

As for joint and bone issues, nothing out of the norm for myself.

Why did she switch u to exemestane?

That’s what I’m taking atm. It just seems like the preferable ai over anastrozole. I’ve had labs done years ago on the same protocol but switched out anastrozole for exemestane. Was using 1/4 tab EOD when I was using anastrozole with that protocol, and then used 1/4 tab of exemestane EOD with the same protocol, and labs for each had my E2 basically identical. So ever since then I’ve always assumed 1mg of anastrozole was basically equivalent to 25mg of exemestane. I’ve also heard quite a few times from other guys that 1 tab of anastrozole is interchangeable with 1 tab of exemestane. So if that’s actually true, it would make sense why u currently feel like ass. Ur basically on the equivalent of 1.5mg of anastrozole per week. Well 2mg/ week if ur doubling ur dose one out of the three days each week that u take it

Definitely post ur labs when they come in. Curious to see what they look like

 

[ggenovez]

I was told exemestane was more powerful. I'm guessing they're hoping I would have better results with that than Anastrazol. Might be changing to something else next week. who knows.

I'll post updates as I get them.

 

[DixieWrecked]

Your posts are a breathe of fresh air because it shows how different we all are. Some people must be more sensitive to estrogen than others.

 

[Vince]

the lower dosage of AI, less than 3.5g/w, I would sleep 10H and feel like crap. At 3.5G/w I'm full of energy and don't have any problems waking up with 6-7h of sleep.

I was just moved to exemestane 25mg tabs. 1/2 tab 3x / week. I feel like ass. just sent in new blood work and I'm waiting. doubled my dose 1 day per week and that makes it tolerable. but nothing like my previous regimen.

I went from looking for a small country to conquer to looking for the early bird special.

1000 IUs/week

I did not notice getting leaner on the higher dose but I was on it for about 2 weeks when I started running out of pills and had to call for a refill and the whole thing came crashing down. That being said, with the energy I had, I think getting leaner would not be an issue. When you go from dragging ass to being on speed, there's a lot of things that happen.

As for joint and bone issues, nothing out of the norm for myself.

I would have a bone density test every year. Have you had one yet?

 

[JA Battle]

I would have a bone density test every year. Have you had one yet?

Is there any idea as to wether e2 or free e2 is necessary to maintain bone density? Because with low shbg his free e2 may still be close to the bottom end of the range.