My Wife legs are sore after being on HRT for 5 months

[Steelballs]

My wife is post menopausal. She has been complaining about her legs, specifically her calfs. I try to massage them but it doesn't help. Ibuprofen doesn't help either. It's affecting her sleep. Here are her levels now:
Progesterone - 4.51 ng/mL
Estradiol - 25.4 pg/mL
FSH - 67.5 mIU/mL
Anyone else experience this? Any help would be great.

 

[Systemlord]

My sisters have lots of aches and pains even years after menopause, they have all of the low estrogen symptoms and their joints are always hurting. My sister fell a couple of years ago and broke her back, she was diagnosed with osteoporosis and hasn't recovered fully and doubt she ever will.

The normal range for FSH in a women is 4.7 to 21.5 mIU/mL, the estrogen and progesterone is low for women.

 

[DorianGray]

Perhaps TRT or hormones are not related. What about other blood results, calcium, potassium, etc.? Can contribute to such symptoms. No weight gain, I assume. Venous insufficiency?