This phenomenon makes me wonder if there would be value in rotating regimens. For example I have had my hormones dialed in on twice weekly dosing, on Natesto, now I am on 14 mg per day daily. Sometimes I will add test cream for a few months. If I switch regimens it is because of side effects, sleep, acne, hematocrit etc but I have years of labs and I have become adept at dialing in new regimens with Defy's help. Now I have been on dailys for a year and everything is perfectly dialed in, but libido has become a significant problem - again. Pt 141 has been effective for occasional use but its not a solution. I will ask Dr Saya about this in my upcoming followup.I got honey moon sometimes when I start or near 40 days and sometimes at the start and at 40 days.