Bump for this. I'm a low SHBG guy as well and having a very hard time getting dialed in. Total T is 550 and free T is very top of range, and e2 is 18. Having crippling anxiety, palpitations, insomnia...
Although I am dropping my fish oil dose because apparently that lowers SHBG.
Very interesting. So basically your free T is fine, but your e2 might be too low hence causing anxiety etc.
But then again, when my e2 is TOO high, I get insomnia?
I dont fucking know man.