low e2 symptoms didnt go away after crash

[GreenMachineX]

I highly doubt fish oil and other OTC supplements are compounding the problem. Possibly the DHEA (which I advocate you stay away from), but not fish oil. At the hight of my issues, I tried to attribute all my symptoms to food intolerance's. I switched to keto for like a year because "carbs made my hot flashes and bloating worse." I then attributed it to caffeine, so i tried cutting that etc etc etc, the list went on. Look at the symptoms of menopause/having a hormone imbalance in general. It can lead to some odd symptoms like tingling, burning in extremities, hot flashes, weight gain, bloating in stomach, digestive issues like GERD and constipation, anxiety, depression, brain fog. I used to be able to drink 3-4 cups a coffee a day in med school before I crashed my e2, after I could barely handle a cup without feeling shaky and sweaty. The weird thing is that now being on Clomid almost a week, I can drink all the coffee I want again and have no issues. My stomach issues and bloating are also gone, as well as my anxiety and brain fog. The only symptoms that are left is occasional fatigue, hot flushing and tingling when I am warm/working out. I will also note the Clomid has decreased my libido slightly and made me experience 1-2 brief depressive episodes a day. These things however are way more manageable compared to how I felt just last week. Honestly, if my wife wasn't a physician as well i am pretty sure should would have left me by now. Thankfully she can empathize with me medically and has tried to help me find a solution after all this time.

As for the thyroid you are correct to assume the above, but what is your thyroid condition. You were hypo, but did anyone test your antibodies (TPO, TGAb,TSI) or diagnose you with Hashimoto's disease? I am only asking because there are weird symptoms attributed with that. I should also note that I have had patients experience some hyper symptoms from their meds, but not all....example (they have average resting HR of 65-75bpm but heat intolerance, mood swings, anxiety, insomnia). If you have been on the same thyroid medication and dose for a long time, but your issues only showed up in the last few months after crashing your e2, I doubt your issues is thyroid in nature. However, if your symptoms have been going on for awhile and you cant attribute it to anything, It honestly could be your thyroid medication. YOU DO NOT have to be hyperthyroid and react oddly to your thyroid meds. Many people feel wired and "off" on them despite having perfect labs" Do you need them? Who diagnosed you with hypothyroid and what were your values?

Personal disclaimer since I am a physician: I am not here to give medical advice, only provide feedback as to what I believe to be true. Everyone should speak with their own doctor before changing their medications around.

Thanks for the reply. Regarding the fish oil, I know it's unlikely, but will still report back in a few more days but do think I'm into something.

With regard to synthroid...I was only diagnosed hypothyroid but I don't have the original labs so I have no idea what they were. I definitely know all the antibodies were negative...all good there. Is there a chance brand name Synthroid might feel different then generic?

 

[MV0334]

Thanks for the reply. Regarding the fish oil, I know it's unlikely, but will still report back in a few more days but do think I'm into something.

With regard to synthroid...I was only diagnosed hypothyroid but I don't have the original labs so I have no idea what they were. I definitely know all the antibodies were negative...all good there. Is there a chance brand name Synthroid might feel different then generic?

I have seen that switching can make a difference, but honestly if you don't have an autoimmune disease you should try to fix the issues with lifestyle modifications (sleep, diet, exercise, stress reduction) if you have not already tried those. Synthetic thyroid medication seems more toxic to me than most meds.

 

[glob]

I have seen that switching can make a difference, but honestly if you don't have an autoimmune disease you should try to fix the issues with lifestyle modifications (sleep, diet, exercise, stress reduction) if you have not already tried those. Synthetic thyroid medication seems more toxic to me than most meds.

Hi! So, are you fine now with clomid?

 

[JA Battle]

I’m going to be trying low dose clomid along side my current protocol. Probably will help due to
My low e2

 

[solothesensei]

Anybody have any estradiol supplementation updates? Still doing it? How are you guys that are doing it feeling?

Update on my estradiol supplementation: Switched from estradiol valerate to cypionate and my dosing requirement has reduced drastically but I am feeling better than ever.

For two months, I have been taking 0.3mg every 2 days and feel fantastic on it. I'm using a 5mg/ml solution. I feel perfectly dialed in unless I accidentally overshoot or undershoot more than 1 unit on the syringe.

 

[JA Battle]

Update on my estradiol supplementation: Switched from estradiol valerate to cypionate and my dosing requirement has reduced drastically but I am feeling better than ever.

For two months, I have been taking 0.3mg every 2 days and feel fantastic on it. I'm using a 5mg/ml solution. I feel perfectly dialed in unless I accidentally overshoot or undershoot more than 1 unit on the syringe.

That is cool. How old are you? Body fat %? Can you rate your libido and eq on a scale of 1-10? On a scale of 1-10 how did you feel before using estradiol? And also currently how do you feel 1-10?

 

[JA Battle]

That is cool. How old are you? Body fat %? Can you rate your libido and eq on a scale of 1-10? On a scale of 1-10 how did you feel before using estradiol? And also currently how do you feel 1-10?

Thanks for this update. Im starting to think about giving estradiol valerate a go or buying some raw enanthate or cypionate.

 

[solothesensei]

That is cool. How old are you? Body fat %? Can you rate your libido and eq on a scale of 1-10? On a scale of 1-10 how did you feel before using estradiol? And also currently how do you feel 1-10?

28 this year. Body fat around 14% (I can see my abs if I squint hard enough under good lighting lol). Libido and EQ are at least a solid 8/10 on most days, 9/10 if I go a few days without any action. My TRT dose is on the higher side though. We don't have the proper tests for FT and E2 here but my TT is 1200.

Before estradiol it was more like 3/10. I needed cialis to get it up and even then I would sometimes not be able to sustain an erection during sex. Increasing T dose did not help. Joint pains and anxiety. It was hell for a couple of years - stay away from aromasin unless you really know what you're doing, guys.

 

[JA Battle]

28 this year. Body fat around 14% (I can see my abs if I squint hard enough under good lighting lol). Libido and EQ are at least a solid 8/10 on most days, 9/10 if I go a few days without any action. My TRT dose is on the higher side though. We don't have the proper tests for FT and E2 here but my TT is 1200.

Before estradiol it was more like 3/10. I needed cialis to get it up and even then I would sometimes not be able to sustain an erection during sex. Increasing T dose did not help. Joint pains and anxiety. It was hell for a couple of years - stay away from aromasin unless you really know what you're doing, guys.

Nice what is t dose and frequency? This is huge news. It would be great to know your e2 number before even if it was standard test. And then it would be dope if you got e2 after sensitive and standard. I have valerate but will be buying cypionate/enanthate now that you said this.

 

[JA Battle]

Nice what is t dose and frequency? This is huge news. It would be great to know your e2 number before even if it was standard test. And then it would be dope if you got e2 after sensitive and standard. I have valerate but will be buying cypionate/enanthate now that you said this.

Also how many weeks until you started to feel a differemce

 

[solothesensei]

Nice what is t dose and frequency? This is huge news. It would be great to know your e2 number before even if it was standard test. And then it would be dope if you got e2 after sensitive and standard. I have valerate but will be buying cypionate/enanthate now that you said this.

T dose is 180mg/week with injections every 2 days. My last E2 test was 31 (TT was 1200) and I still felt like crap. T:E ratio was nearly 40:1.

Yeah there's just something about E2 cypionate. If you trawl through the trans MtF forums, you'll see some anecdotes that cypionate is more potent mg for mg than valerate. I never felt 100% right with the valerate either. I have no explanation for either of these, just an n=1 observation.

I overdosed my first E2 cyp (IM) injection lol so I guess you could say I felt amazing within 3 hours, which then became more like bitchiness and a funny feeling in my nipples after 12 hours.

 

[JA Battle]

T dose is 180mg/week with injections every 2 days. My last E2 test was 31 (TT was 1200) and I still felt like crap. T:E ratio was nearly 40:1.

Yeah there's just something about E2 cypionate. If you trawl through the trans MtF forums, you'll see some anecdotes that cypionate is more potent mg for mg than valerate. I never felt 100% right with the valerate either. I have no explanation for either of these, just an n=1 observation.

I overdosed my first E2 cyp (IM) injection lol so I guess you could say I felt amazing within 3 hours, which then became more like bitchiness and a funny feeling in my nipples after 12 hours.

Maybe you were just taking too much valerate. As valerate has more estrogen per mg than cypionate. But there may be a small peak and trough with such a small dose.

I’m really interested to see some kind of e2 test while you are feeling go. It would be great information for us on this forum.

Glad your feeling great!

 

[JA Battle]

T dose is 180mg/week with injections every 2 days. My last E2 test was 31 (TT was 1200) and I still felt like crap. T:E ratio was nearly 40:1.

Yeah there's just something about E2 cypionate. If you trawl through the trans MtF forums, you'll see some anecdotes that cypionate is more potent mg for mg than valerate. I never felt 100% right with the valerate either. I have no explanation for either of these, just an n=1 observation.

I overdosed my first E2 cyp (IM) injection lol so I guess you could say I felt amazing within 3 hours, which then became more like bitchiness and a funny feeling in my nipples after 12 hours.

Do you still use cialis?

 

[solothesensei]

Do you still use cialis?

Not at all. I never have to now, which I'm really thankful to the E2 cyp for.

 

[Match]

Do Estrogen Blockers Work for Bodybuilding?

Learn about how estrogen blockers can actually be harmful for bodybuilding and the different side effects they can cause.

jayccampbell.com

Reducing Estradiol does not seem to be a good choice. Would it then be only in Estradiol cases too high, extreme?

 

[GreenMachineX]

Has anyone tried ground flaxseed to bring estrogen up? Check this video out. I just got my estradiol result and it was 11. I started ecdysterone yesterday and will be taking 2 tbsp ground flaxseed starting today.

 

[Gman86]

Has anyone tried ground flaxseed to bring estrogen up? Check this video out. I just got my estradiol result and it was 11. I started ecdysterone yesterday and will be taking 2 tbsp ground flaxseed starting today.

Increasing ur test dose isn’t an option?

 

[GreenMachineX]

Increasing ur test dose isn’t an option?

At trough, my free T is top of range already. When I did try to go up a few mg for a few days, it resulted in anxiety symptoms (I'm guessing that's what they were) so bad I went to the ER. Chest tightness, jitters/tremors, shortness of breath, rapid heat rate, etc. And my HCT is already at 52. I'm thinking the only way for me to convert enough E from T is the EOD or less protocol, but those protocols keep my blood pressure too high from the spike in T. My blood pressure has never been this good in my life. So if I can find a way to replace the E without increasing test dose, it'll be best for longevity.

 

[Gman86]

At trough, my free T is top of range already. When I did try to go up a few mg for a few days, it resulted in anxiety symptoms (I'm guessing that's what they were) so bad I went to the ER. Chest tightness, jitters/tremors, shortness of breath, rapid heat rate, etc. And my HCT is already at 52. I'm thinking the only way for me to convert enough E from T is the EOD or less protocol, but those protocols keep my blood pressure too high from the spike in T. My blood pressure has never been this good in my life. So if I can find a way to replace the E without increasing test dose, it'll be best for longevity.

Wow, definitely a conundrum for sure. Can’t believe ur E2 is only 11! Any idea why ur such a low aromatizer?

 

[GreenMachineX]

Wow, definitely a conundrum for sure. Can’t believe ur E2 is only 11! Any idea why ur such a low aromatizer?

I can only guess that it's due to messing with androgens and things like androstenetrione, aromasin, and other anti-e's over the years. It's been hell trying to get dialed in over the years.