Crisler wasn't new to this. Between his bodybuilding days and post bodybuilding career he was probably on some from or another of anabolics for 20 years? And he was very much a proponent of using the lowest doses needed to relieve symptoms, Its not like he was blasting. I find it hard to believe anything he was doing now is what pushed him over the edge.
I have read some people speculate that it was the fights he was having with the other notable TRT practitioners over AIs that may have contributed, when basically the entire TRT world became anti AI and he stayed relatively pro AI. Who knows? People want answers to unanswerable questions I guess.
Anyone who suffers from depression will tell you that sometimes you just can't escape the darkness no matter how hard you try.