Started TRT Tuesday at 200mg weekly with regular testing to determine dosing adjustments. My next injection is actually on mondays moving forward so Im only 4 days out from the next injection. My problem right now is my low E2 and its wrecking my bones and joints with pain. It was under range on the "regular" testing so its safe to assume its tanked. I know this takes time, I was on TRT before but the doc wasn't dosing me high enough and at the time I associated the side effects of too little Testosterone and E2 with the treatment (75mg weekly). After trying and failing monotherapy with Clomid I have made the decision to continue for life with TRT. I am age 37, with low LH production from an unknown "idiopathic" cause. After over 2 years of specialist after specialist and all the cost and stress on my family I decided the time for looking for answers is over. So long story short, I have DHEA and Pregnenolone on hand, could high dosing on DHEA help to bring my estradiol up? I have no concern for high E2 at the moment if i over shoot, I just need some relief from this bone and joint pain. I also have a supply of clomid that I just stopped on Tuesday, would that help convert to estradiol faster? Thanks for any tips.