Hi everyone, I am very new to this journey of hormone therapy and I am looking for some insight and experiences in regards to the current issues I’m dealing with. I was diagnosed with acromegaly and had a pituitary tumor that was removed in February of this year. The tumor caused damage to my pituitary gland and as a result I developed hypothyroidism as well as secondary hypogonadism. My medication regiment for the past few months has consisted of daily Synthroid 137 mcg, hydrocortisone 20 to 30 mg daily to account for lower cortisol levels, and HCG monotherapy injected twice a week. I also take 5 mg cialis daily. For the first month or so of this treatment plan I felt great and the erectile dysfunction problems I had struggled with previously disappeared and I was able to achieve and maintain quality erections throughout the day. However, over the past two months plus the benefits of raising my testosterone have seemingly disappeared and I am experiencing soft erections and am not able to maintain my erections. I suspected this was potentially due to elevated E2 levels as my E2 levels have always registered as above the normal range since I was 18 and while going through puberty I developed man boobs. I am 23 now and additional bloodwork has confirmed my E2 as elevated. Me and my doctor have experimented with different dosages of HCG in an attempt to find a sweet spot with maintaining a strong testosterone level but also dialing back the E2. When I first started I was injecting 4500 iu twice a week which got my testosterone levels into the 1100s. We then proceeded to dial back the amount of HCG and have continued to do so. On my last lab results, my testosterone level was at 868 and my E2 was at 66. All other bloodwork was normal. I would also like to add that nothing else in my medication regiment or bloodwork has changed or fluctuated since starting treatment. This had led me to believe that my elevated E2 is the culprit causing my issues. I hypothesize that when I first started treatment my testosterone levels were boosted which caused me to feel great but as time passed my E2 caught up and elevated as well and that is what caused the benefits of my increased testosterone to disappear. I would like to hear others opinions and insights on this and also if anyone has experienced something similar in terms of elevated E2 levels canceling out the benefits they experienced from boosted testosterone. Thank you.
