How to improve penile sensitivity?

[M.J]

I’ve had issues with penis sensitivity where I could go on forever but had a hard time reaching orgasm. What I discovered in my situation that when this occurred it seems to be due to high estradiol. Therefore, when I start to notice this I take .25mg anastrozole and the problem resolves. Most of the time I have excellent penis sensitivity.

I’ll add that I keep my testosterone level at the top of the range.

I am thinking this could be the issue at least to some level, because when I do my lab test before my injection my estradiol is already at the top of the reference.
So maybe it does help reducing a bit my t injection. I have done some calculation and 16mg EOD for me may solve this. Also will help with my high hemoglobin. starting my protocol today.

 

[BJE]

I am thinking this could be the issue at least to some level, because when I do my lab test before my injection my estradiol is already at the top of the reference.
So maybe it does help reducing a bit my t injection. I have done some calculation and 16mg EOD for me may solve this. Also will help with my high hemoglobin. starting my protocol today.

I inject 60mg every three days. I use HCG as well.

 

[sirgawain]

I’ve had issues with penis sensitivity where I could go on forever but had a hard time reaching orgasm. What I discovered in my situation that when this occurred it seems to be due to high estradiol. Therefore, when I start to notice this I take .25mg anastrozole and the problem resolves. Most of the time I have excellent penis sensitivity.

I’ll add that I keep my testosterone level at the top of the range.

Interesting -- so how soon after you take the AI does the sensitivity return? I assume it's a one-off when you do it and not a weekly AI dose.

 

[Fernando Almaguer]

Don't touch ones penis for a good week. Some if not a lot of sensitivity will return. My anecdotal assessment.

 

[Anonymon]

My penile sensitivity goes up when, in no particular order:

1. My free t is lower
2. My E2 is higher (right now it’s around 79)
3. I have more T4 in my system (in my case from levothyroxine)
4. I have smaller T3 hits throughout the morning (6.25-12.5mcg of liothyronine up to 31ishmcg total or more)
5. I use something like ashwagandha at night when I’m on T4 to dramatically increase T4 conversion (3.4 free T3 to a 4.6 kind of difference)
6. It’s been longer since I’ve ejaculated

Actually started experimenting with Ash at night while on T4 to help with coming off selegiline and I think about sex pretty much all day and night now. I can see why guys join OnlyFans if they can get this horny. I could hardly sit down to poop because I’d pop a boner in there. Monumental difference.

PT-141 makes me think more about sex eventually and the thoughts are more enjoyable, but did nothing for penile sensitivity, and in general I didn’t feel like it was worth it.

Cialis makes it go down a little.

 

[BJE]

Interesting -- so how soon after you take the AI does the sensitivity return? I assume it's a one-off when you do it and not a weekly AI dose.

Maybe a day. I usually don’t take more that 1/4 Arimidex pill every two weeks.

 

[sirgawain]

Revisiting this as I am struggling more with the sensitivity, something that Trimix doesn't help with...

So at my last test, back in October, I was on 7 units of T per week (split into 3.5 shots, mon/thur, sub-q). I also do HCG (500 UI) 2x a week.

T: 1219
E: 36 (pg/mL)

Doc felt the T was too high and pulled me down to 6 units a week. We haven't had a followup test yet since moving to the new number. I suspect it may still be a touch too high, but we'll see what happens.

What I do know is that I still have low sensitivity, and my libido is a ball of "meh." I am at teenager T levels, but I am not feeling T level sexual energy.

 

[Nelson Vergel]

Revisiting this as I am struggling more with the sensitivity, something that Trimix doesn't help with...

So at my last test, back in October, I was on 7 units of T per week (split into 3.5 shots, mon/thur, sub-q). I also do HCG (500 UI) 2x a week.

T: 1219
E: 36 (pg/mL)

Doc felt the T was too high and pulled me down to 6 units a week. We haven't had a followup test yet since moving to the new number. I suspect it may still be a touch too high, but we'll see what happens.

What I do know is that I still have low sensitivity, and my libido is a ball of "meh." I am at teenager T levels, but I am not feeling T level sexual energy.

What other medications are you taking ?

 

[sirgawain]

What other medications are you taking ?

I take a 5mg Cialis daily, warfarin, and supplements like ZMA and fish oil. That's it. (and the aforementioned trimix, which I wish I didn't have to use, but am grateful exists).

 

[M.J]

Revisiting this as I am struggling more with the sensitivity, something that Trimix doesn't help with...

So at my last test, back in October, I was on 7 units of T per week (split into 3.5 shots, mon/thur, sub-q). I also do HCG (500 UI) 2x a week.

T: 1219
E: 36 (pg/mL)

Doc felt the T was too high and pulled me down to 6 units a week. We haven't had a followup test yet since moving to the new number. I suspect it may still be a touch too high, but we'll see what happens.

What I do know is that I still have low sensitivity, and my libido is a ball of "meh." I am at teenager T levels, but I am not feeling T level sexual energy.

I feel We all struggling with libido

 

[sammmy]

I take a 5mg Cialis daily, warfarin, and supplements like ZMA and fish oil. That's it. (and the aforementioned trimix, which I wish I didn't have to use, but am grateful exists).

I would drop the Magnesium. It has analgesic activity i.e. is capable of suppressing pain and nerve sensitivity in general:

Although some debate exists concerning the role of magnesium sulphate as an analgesic adjuvant, the consensus is that magnesium sulphate acts to support a neuromuscular blockade. Magnesium acts as a calcium channel blocker at presynaptic nerve terminals and reduces acetylcholine release at the motor endplate (Fisher, 1999). This diminishes muscle fibre excitability and reduces end plate potential amplitudes, which leads to the potentiation of a neuromuscular blockade by nondepolarizing neuromuscular blockers (Fisher, 1999). Some authors have focused on the direct effect of magnesium on neuromuscular blockade (Fuchs-Buder et al., 1995; Fuchs-Buder and Tassonyi, 1996; Kussman et al., 1997; Ross and Baker, 1996; Telci et al., 2002), whereas others concluded that a perioperative adjuvant magnesium infusion enhances neuromuscular blockade (Lee and Kwon 2009; Oguzhan et al., 2008; Ryu et al., 2008; Ryu et al., 2009; Seyhan et al., 2006).

 

[hefab]

Give L-Arginine a try, at least 1000mg. It worked for me for a while and then tapered off. Not sure if my body adjusted to it or what, but for a few months sensitivity was amazing.

Can I use citruline?

 

[sammmy]

Arginine and it's precursors Citrulline or Glutamine work as vasodilators and improve erection, similar to Viagra/Cialis.

Penis sensitivity is not about erection - you can have erection and still not feel pleasure from friction at your penis - it feels like rubbing your finger instead.

 

[Golfboy307]

Respectfully disagree on your comment Sammy. At least in my experience, when sensitivity is heightened it creates a much better erection. The positive stimulus leads to better blood flow and a longer erection at least for me. It is like a positive feedback loop.

 

[sammmy]

"Penis sensitivity" is not about getting an erection when you touch your penis. Penis sensitivity is about feeling pleasure when you touch your penis AFTER you have an erection.

To me, these are two completely different things: I get a perfect erection but delayed orgasm because I do not feel pleasure when rubbing penis after that. Pleasure turns on only 5 seconds before orgasm. This is what it means to not have penis sensitivity. That is also the problem created by the SSRI antidepressants - erection without pleasure.

Erection and penis sensitivity after erection are controlled by different parts of the nervous system. That's why Viagra/Cialis can get you an erection but actually will make the penis less sensitive after that - they say will numb you up.

This forum and many doctors keep confusing different parts of sexuality: libido, erection, penis sensitivity after erection, ejaculation, orgasm are distinct components. If you don't start making difference, you will get nowhere understanding how to treat those.

 

[Nelson Vergel]

I take a 5mg Cialis daily, warfarin, and supplements like ZMA and fish oil. That's it. (and the aforementioned trimix, which I wish I didn't have to use, but am grateful exists).

Did you have better penis sensitivity before you started warfarin? Did you have a DVT?

 

[Nelson Vergel]

I will reach out to these clinicians since they are actually measuring penile sensitivity.

MP74-07 THE PENILE SENSITIVITY RATIO: OPTIMIZATION OF A BIOTHESIOMETRY PARAMETER TO ASSESS CHANGES IN PENILE SENSITIVITY
Peter Tsambarlis, Adam Wiggins, M. Ryan Farrell, and Laurence Levine

INTRODUCTION AND OBJECTIVES
Penile sensitivity ratio (PSR) was previously developed at our institution to standardize biothesiometry data and reduce variability. Significant associations with PSR were reported diminished sensation, age, and Peyronie's disease (PD). We sought to optimize the input variables comprising the PSR.

METHODS
We performed a retrospective analysis of all men who underwent biothesiometry at a single urology practice specializing in men's health from 7/2013-5/2017. PSR was initially defined as the mean biothesiometry threshold for sensation of the dorsal and ventral glans divided by the mean sensation threshold of the left and right index finger. Thus, a higher PSR indicates diminished penile sensation. We compared this ratio to models which included biothesiometry data from the penile shaft and anterior thigh. Univariate and multiple regression analyses were performed for each iteration of the ratio. Patient factors included: age, diabetes mellitus (DM), PD, erectile dysfunction (ED), ejaculatory dysfunction (premature vs. delayed vs. normal function), and subjective diminished sensation.

RESULTS
Our analysis included 1239 men with mean age of 53.2 years (SD=14.0 years). The original PSR was significantly higher in men who reported diminished sensitivity compared to men who reported normal penile sensation, 2.09 and 1.94 respectively (p =0.01). Adding mean left and right shaft to the numerator and mean left and right thigh data to the denominator of the previously described PSR lead to a model in which diminished sensitivity did not affect the ratio (p = 0.20). Alternatively, when glans and shaft data were included against the index fingers only, reported diminished sensitivity increased the ratio (p=0.03). On multiple regression analysis using the ratio of the mean glans and shaft values divided by the mean index finger values, the ratio was significantly affected by age, DM, and PD, but not reported diminished sensation.

CONCLUSIONS
The current analysis does not support the inclusion of data from the shaft or thigh, as reported diminished sensation did not affect these ratios, suggesting a lack of internal validity. The original PSR using data from the glans and index fingers appears to most accurately represent clinically significant changes in penile sensitivity. Further prospective data collection including other internal controls such as the cheek may further optimize the PSR.

American Urological Association

 

[Gianluca]

normalizing DHEA-s levels can also improve penis sensitivity

 

[Anonymon]

My sensitivity still goes up when I take levothyroxine at night. Also goes up on licorice root extract. Dicks are way more complicated than they need to be.

 

[sirgawain]

Did you have better penis sensitivity before you started warfarin? Did you have a DVT?

My penis journey...I had an illness which took out my heart valve. So I got an artificial one, which is why I have the warfarin. The illness also hit my nerves, particularly the one that affects the penis. I lost about 60% of the sensitivity of my penis in that event. But I was still functional, could orgasm...just had to adjust positions and make sure my sensitive pieces hit the right parts (mainly the glans). I became, for the shaft, more sensitive to pressure than friction.

Then I started TRT, which made me feel better, changed my body comp, but lowered my already lowered sensitivity.

After starting TRT, I noticed I was losing my erections quicker than usual. I couldn't make it through a session. Tried the usual drugs and they don't have an effect. So, I had to resort to Trimix, and that also had a lowering effect on sensitivity.

So, essentially, I'm in a perfect storm of wanting desperately to find a way to increase my sensitivity, or remove my reliance on Trimix (I take a very small dose of 3 units).

I don't know if I was better off never doing TRT in the first. I have so many drugs affecting me, that are, at this point, hard to stop and I am not clear what to do. It's so in my head too, and I feel "less than" and get mild anxiety when we start sex because I can pretty much tell 10 mins in if I am sensitive enough that I'm going to be able to finish the normal way and not with my hand.

I am so physically different than I was just 8 years ago.