Erection & Orgasm Quality

[BJE]

I suspected that it could be E2 related. I am at 35 right now. I started at like 6 or 7. When I was at 65 to 70 I was almost 100% impotent - so I know it does affect me.

I am at a cross roads right now with treatment. I was going to increase dosage on the next shot day (Sunday) but now I have a possible kidney problem that we need to explore. If it's related to the TRT I may have to stop it. That means my life is basically over. I felt like hell on earth before I started TRT.

I had been doing fine then in a short period of time I lost sensation and orgasm. I had my E2 checked and it was something like 58. I’d never seen it that high. It’s usually around 20-30. I took arimidex, probably around 1.5mg m, I hadn’t been using much at all. Within two days my sex was back full force. Some time later it happened again and arimidex solved the problem again. I didn’t have bloodwork done. Otherwise I’m not really using any Arimidex.

I don’t understand how testosterone could possibly adversely affect the kidneys.

 

[Mr S]

I just ordered more this morning. I order it from Walmart Specialty Pharmacy. My insurance won’t pay for it. The cost with a GoodRx coupon was $108.57 for one 10000IU vial of Pregnyl brand. Shipping is free and the also send free insulin syringes as prescribed by my doctor and alcohol wipes.

Thank you for the information. Pregnyl is the least expensive option with a GoodRx coupon I checked. It’s interesting that when I looked up for compounded HCG I always get an HCG diet website and it’s much more expensive even though it’s made by a compounding pharmacy. I discarded this way to get HCG as the 5,000iu vial goes for at least 249$ whereas I can get 10,000iu of Pregnyl for the price you listed above.

 

[CSI007]

I had been doing fine then in a short period of time I lost sensation and orgasm. I had my E2 checked and it was something like 58. I’d never seen it that high. It’s usually around 20-30. I took arimidex, probably around 1.5mg m, I hadn’t been using much at all. Within two days my sex was back full force. Some time later it happened again and arimidex solved the problem again. I didn’t have bloodwork done. Otherwise I’m not really using any Arimidex.

I don’t understand how testosterone could possibly adversely affect the kidneys.

Im not sure that it is the T, yet. Doing a little digging it seems that there have been a few instances were T has caused issues with renal values going way up and this was repeatable/reversable and obvious through ultra sound testing of the kidneys. I guess I will find out soon enough.

 

[Mr S]

Before TRT ED drugs had no effect on me. With TRT they work really well. I think for them to work you need a good hormone level.

You’re correct. Hypogonadism will affect erections that viagra can’t help to improve. I read that during some Viagra studies men with low testosterone weren’t allowed to participate for that reason.

 

[BJE]

You’re correct. Hypogonadism will affect erections that viagra can’t help to improve. I read that during some Viagra studies men with low testosterone weren’t allowed to participate for that reason.

Before TRT I could take 100mg Viagra and remain totally limp.

 

[wsj357]

I suspected that it could be E2 related. I am at 35 right now. I started at like 6 or 7. When I was at 65 to 70 I was almost 100% impotent - so I know it does affect me.

I am at a cross roads right now with treatment. I was going to increase dosage on the next shot day (Sunday) but now I have a possible kidney problem that we need to explore. If it's related to the TRT I may have to stop it. That means my life is basically over. I felt like hell on earth before I started TRT.

I wouldn’t do that regardless of what they think. I would have a TRT specialist consult this guy with the kidney specialty.

if anything trt will only help. I haven’t found any Kinsey related issues with trt during my research.

 

[CSI007]

I wouldn’t do that regardless of what they think. I would have a TRT specialist consult this guy with the kidney specialty.

if anything trt will only help. I haven’t found any Kinsey related issues with trt during my research.

Well, let's hope I don't have to do anything. Will move forward after I get this urinalsys done this week. That should hopefully shed some light on this.

Looking back at all my blood work, I had normal kidney function, then started TRT and within 6 months my creatinine was rising and my eGFR started to tank. Maybe it's a coincidence but then again may be not.

With regards to TRT and kidney function. I did find an article were a patient was having adverse affects to T with regards to kidney function. When it was removed his values went back to normal. When added again they his kidney function tanked. It was much worse though and very quick though. More of an acute attack on his kidneys from the T.

 

[BJE]

Well, let's hope I don't have to do anything. Will move forward after I get this urinalsys done this week. That should hopefully shed some light on this.

Looking back at all my blood work, I had normal kidney function, then started TRT and within 6 months my creatinine was rising and my eGFR started to tank. Maybe it's a coincidence but then again may be not.

With regards to TRT and kidney function. I did find an article were a patient was having adverse affects to T with regards to kidney function. When it was removed his values went back to normal. When added again they his kidney function tanked. It was much worse though and very quick though. More of an acute attack on his kidneys from the T.

What has your GFR been? Mine has tested low but has always bounced back. My GFR has been as low as 53 but is usually between the mid 60’s to low 70’s. When I’ve asked my doctor about it being somewhat low his response has been that it just because I’m getting older but nothing to worry about.

 

[CSI007]

What has your GFR been? Mine has tested low but has always bounced back. My GFR has been as low as 53 but is usually between the mid 60’s to low 70’s. When I’ve asked my doctor about it being somewhat low his response has been that it just because I’m getting older but nothing to worry about.

In early 2016 before I started TRT my creatinine was .92 and my eGFR was 98. a year later it was 1.14 and eGFR in the 80s. Last year it was 1.15 and 77 - last week it was 1.22 and 70. Steady rise in creatinine and rather significant drop in eGFR. eGFR is basically a measure of your kidney function, so if your in the 70s you only have 70% of function. Everything i read says that is stage 2 kidney disease if there is signifcant amount of protein and creatinine in the urine.

 

[BJE]

In early 2016 before I started TRT my creatinine was .92 and my eGFR was 98. a year later it was 1.14 and eGFR in the 80s. Last year it was 1.15 and 77 - last week it was 1.22 and 70. Steady rise in creatinine and rather significant drop in eGFR. eGFR is basically a measure of your kidney function, so if your in the 70s you only have 70% of function. Everything i read says that is stage 2 kidney disease if there is signifcant amount of protein and creatinine in the urine.

How old are you. I don’t think my GFR has been higher than the 70’s since my early 40’s. I’ve also been told that men who workout have higher creatinine levels due to muscle tissue breakdown or something and also if you are somewhat dehydrated such as when fasting before a blood test that it can lower your GFR

 

[Mr S]

In early 2016 before I started TRT my creatinine was .92 and my eGFR was 98. a year later it was 1.14 and eGFR in the 80s. Last year it was 1.15 and 77 - last week it was 1.22 and 70. Steady rise in creatinine and rather significant drop in eGFR. eGFR is basically a measure of your kidney function, so if your in the 70s you only have 70% of function. Everything i read says that is stage 2 kidney disease if there is signifcant amount of protein and creatinine in the urine.

Is this the article you are referring to? Rather interesting
Is Testosterone Detrimental to Renal Function?

 

[CSI007]

How old are you. I don’t think my GFR has been higher than the 70’s since my early 40’s. I’ve also been told that men who workout have higher creatininin the levels due to muscle tissue breakdown or something and also if you are somewhat dehydrated such as when fasting before a blood test that it can lower your GFR

Just turned 48. I can only comment on what I have read but each year we lose about 1% of kidney function as we age. The normal value for my age is I think in the 90s still. 70 is where a 90 year old man would be. I'm glad to hear that your values increased some over your low point. Its encouraging to hear that.

I have thought about the increase in creatinine thing being muscle related. Since I started TRT my muscles have really bulked up - but it's not because I am working out. They simply have gotten back to the way they were before my T started to tank. I lost a lot of muscle mass in the years leading up to TRT.

Should have a clearer picture once the urinalyses comes back.

 

[BJE]

Just turned 48. I can only comment on what I have read but each year we lose about 1% of kidney function as we age. The normal value for my age is I think in the 90s still. 70 is where a 90 year old man would be. I'm glad to hear that your values increased some over your low point. Its encouraging to hear that.

I have thought about the increase in creatinine thing being muscle related. Since I started TRT my muscles have really bulked up - but it's not because I am working out. They simply have gotten back to the way they were before my T started to tank. I lost a lot of muscle mass in the years leading up to TRT.

Should have a clearer picture once the urinalyses comes back.

What is the urinalysis supposed to determine? Protein in the urine? I’ve never had an indicator of protein in my urine.

 

[CSI007]

What is the urinalysis supposed to determine?

It is a 24 hour collection. It will measure the amount (if any) protein in the urine and the ratio. Here is a definition:

One of the tests is called the protein to creatinine ratio. It is the most accurate way to measure protein in the urine. ... A value of less than 30 mg/gm per day is normal for the albumin to creatinine ratio; a value of 30 mg/gm per day or higher is high and may be a sign of early kidney disease.

 

[Vince Carter]

I will piggyback on the Creatinine testing part in so much as it's not accounting for and it should be in the matrix for assessing your kidney function, increased muscle mass. A high protein diet, weight training, and so forth can all influence Creatinine values. It's a very common thing in this category of muscle and weight training, if that applies to you. I'm unsure of this basic "it's Testosterone" business and being detrimental to renal function.

 

[wsj357]

I will piggyback on the Creatinine testing part in so much as it's not accounting for and it should be in the matrix for assessing your kidney function, increased muscle mass. A high protein diet, weight training, and so forth can all influence Creatinine values. It's a very common thing in this category of muscle and weight training, if that applies to you. I'm unsure of this basic "it's Testosterone" business and being detrimental to renal function.

The docs are working with ranges and not looking at the unique situation of the patient.

Maybe a different type of application like scrotul might work better for him since it’s absorbed quickly and does not have to prices through the liver and etc

 

[Vince Carter]

I can usually get under the Creatinine value by being off from the gym for ~72hrs before hand, but not always, and always fasted, too. Not being fasted will grow your Creatinine values, too.

 

[wsj357]

Well, let's hope I don't have to do anything. Will move forward after I get this urinalsys done this week. That should hopefully shed some light on this.

Looking back at all my blood work, I had normal kidney function, then started TRT and within 6 months my creatinine was rising and my eGFR started to tank. Maybe it's a coincidence but then again may be not.

With regards to TRT and kidney function. I did find an article were a patient was having adverse affects to T with regards to kidney function. When it was removed his values went back to normal. When added again they his kidney function tanked. It was much worse though and very quick though. More of an acute attack on his kidneys from the T.

If it does turn out to be the testosterone I suggest looking into different esters like grape seed and better yet trying the scrotum applied T cream. I’ve read men talk about bkood pressure rising + other weird sides on cypionate and upon changing to grape seed oil the issues resolved.

I would think the scrotum cream is a great choice because it does not store in the fat, it does not have to prices through the liver and it’s an immediate dose.

Jsut food for thought. I’d hate to see someone get off TRT and not have different options and opinions available to them.

Take care brother