It does mention estrogen as a possible contributing factor to autoimmune response. However, they have no conclusive evidence to show what role it plays at this time, especially in terms of COVID-19.
However, it does beg the question...’if estrogen levels in women increase autoimmune response to certain viruses such as COVID-19, should men stop knocking down their E2 levels with Anastrozole during these time periods to increase their immune response?’
Unfortunately, due to the hyper-politicized nature of testosterone use, we will likely never see studies on that.