TestAdvocate
Member
Seems like Tadafil along with the AI has tanked my E2. I have been taking Tadafil 10mg daily maint dose for a little over two years. I was also taking prescribed AI, twice weekly. My 6 month lab review just a few weeks ago shows my E2 has crashed to almost zero.......my symptoms are achy knees and low libido. The suspicion is the Cialis and the AI together has crashed my E2. We decided to quit using the AI to allow my E2 to get back up to at least 25. It's been a few weeks.......libido has gone back up, the achy knees are still there. I'll get labs again in just a few weeks to see if E2 has gone back up to the desired level.